Literature DB >> 23055887

Probiotics and prebiotics: why are they "bugging" us in the pharmacy?

Timothy Ulbrich1, Steve Plogsted, Maureen E Geraghty, Kristina M Reber, Christina J Valentine.   

Abstract

OBJECTIVES: Specific organisms can be added to foods to target an effect (probiotics) or non-digestible carbohydrates can be used to foster the development of a favorable flora in the intestinal tract (prebiotics). The significance of pro- and prebiotics have been studied extensively, providing many current and theoretical treatment options. The objective of this paper is to provide a brief overview of commercial products available for the practicing clinician.
METHODS: The literature was evaluated for the most commonly used and studied pre- and probiotics available. In addition, information regarding each of the products was obtained from the manufacturer.
RESULTS: We found that all products are not formulated the same and the content of live organisms can differ. Currently available products are relatively safe but caution should be used for any patients that may have allergies to inactive ingredients in the product or are immunocompromised.
CONCLUSIONS: Many probiotics and prebiotics are commercially available to aid in promoting healthy bowel flora to resist disease. This reference can be a helpful tool for the pharmacist when answering questions or making recommendations to a patient.

Entities:  

Keywords:  diet; organisms; prebiotics; probiotics; supplements

Year:  2009        PMID: 23055887      PMCID: PMC3461992          DOI: 10.5863/1551-6776-14.1.17

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  22 in total

Review 1.  Probiotics and prebiotics: can regulating the activities of intestinal bacteria benefit health?

Authors:  G T Macfarlane; J H Cummings
Journal:  BMJ       Date:  1999-04-10

2.  Safe and efficacious probiotics: what are they?

Authors:  Gregor Reid
Journal:  Trends Microbiol       Date:  2006-06-30       Impact factor: 17.079

Review 3.  Microbes and the developing gastrointestinal tract.

Authors:  Josef Neu; Martha Douglas-Escobar; Mariela Lopez
Journal:  Nutr Clin Pract       Date:  2007-04       Impact factor: 3.080

4.  Probiotics may be unsafe in infants allergic to cow's milk.

Authors:  D A Moneret-Vautrin; M Morisset; V Cordebar; F Codréanu; G Kanny
Journal:  Allergy       Date:  2006-04       Impact factor: 13.146

Review 5.  Exploiting Bifidobacterium genomes: the molecular basis of stress response.

Authors:  Juliano De Dea Lindner; Carlos Canchaya; Ziding Zhang; Erasmo Neviani; Gerald F Fitzgerald; Douwe van Sinderen; Marco Ventura
Journal:  Int J Food Microbiol       Date:  2007-06-14       Impact factor: 5.277

6.  Real-time PCR quantitation of clostridia in feces of autistic children.

Authors:  Yuli Song; Chengxu Liu; Sydney M Finegold
Journal:  Appl Environ Microbiol       Date:  2004-11       Impact factor: 4.792

7.  Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants.

Authors:  Hung-Chih Lin; Bai-Horng Su; An-Chyi Chen; Tsung-Wen Lin; Chang-Hai Tsai; Tsu-Fuh Yeh; William Oh
Journal:  Pediatrics       Date:  2005-01       Impact factor: 7.124

8.  Oral bacterial therapy reduces the duration of symptoms and of viral excretion in children with mild diarrhea.

Authors:  A Guarino; R B Canani; M I Spagnuolo; F Albano; L Di Benedetto
Journal:  J Pediatr Gastroenterol Nutr       Date:  1997-11       Impact factor: 2.839

9.  The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut.

Authors:  Patricia W Lin; Tala R Nasr; Andrew J Berardinelli; Amrita Kumar; Andrew S Neish
Journal:  Pediatr Res       Date:  2008-11       Impact factor: 3.756

Review 10.  Use of probiotics in pediatrics: rationale, mechanisms of action, and practical aspects.

Authors:  Jose M Saavedra
Journal:  Nutr Clin Pract       Date:  2007-06       Impact factor: 3.080

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  1 in total

1.  Gut microbiome dysbiosis in patients with hepatitis B virus-related hepatocellular carcinoma after extended hepatectomy liver failure.

Authors:  Yu-Chong Peng; Jing-Xuan Xu; Chuan-Fa Zeng; Xin-Hua Zhao; Le-Qun Li; Lu-Nan Qi
Journal:  Ann Transl Med       Date:  2022-05
  1 in total

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