Literature DB >> 23052504

Histological characterization of appendectomy specimens with intraoperative appearance of vascular injection.

Marty Zdichavsky1, Hannes Gögele, Gregor Blank, Miriam Kraulich, Tobias Meile, Maximilian von Feilitzsch, Dörte Wichmann, Alfred Königsrainer.   

Abstract

BACKGROUND: Acute appendicitis frequently needs acute surgical intervention. Laparoscopic appendectomy (LA) and conventional open appendectomy (OA) are well established procedures, but appendectomy for intraoperative inconspicuous or vascular injected appendixes remains under debate because of potential postoperative morbidity. The aim of this study was to correlate intraoperative nonacute appendixes with histological and clinical outcome.
METHODS: Between 2005 and 2009, a total of 1,017 patients underwent OA or LA. A total of 1,005 patients were enrolled with inclusion criteria of suspicious acute appendicitis preoperatively. One hundred twenty-nine of 1,005 patients had intraoperative normal, vascular injected or chronic appendixes that were defined as nonacute appendicitis. Intraoperative findings were correlated with histological results and clinical outcome of patients.
RESULTS: Of 129 (12.8 %) of 1,005 patients with macroscopically nonacute appendicitis intraoperatively, 16.3 % had normal findings, 81.4 % vascular injection, and 2.3 % chronic alterations; and 94.6 % of nonacute appendixes had histopathological alterations: 38.9 % chronic, 14.0 % neurogenic, 26.4 % acute, 13.2 % phlegmonous, and 2.3 % malignant. Coproliths were found in 21.7 % of patients, most in vascular injected appendixes. Four of seven patients with histopathological normal appendixes had coproliths. Morbidity rate was 2.3 %, with no mortality.
CONCLUSIONS: Appendiceal resection for intraoperative nonacute appendixes should be recommended because of high incidence of histopathological findings with low morbidity. In particular, chronic and neurogenous alterations cannot be predicted clinically or verified by radiological examination, but may cause recurrent symptoms.

Entities:  

Mesh:

Year:  2012        PMID: 23052504     DOI: 10.1007/s00464-012-2523-x

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  26 in total

1.  Negative appendectomy: a 10-year review of a nationally representative sample.

Authors:  Shiva A Seetahal; Oluwaseyi B Bolorunduro; Trishanna C Sookdeo; Tolulope A Oyetunji; Wendy R Greene; Wayne Frederick; Edward E Cornwell; David C Chang; Suryanarayana M Siram
Journal:  Am J Surg       Date:  2011-04       Impact factor: 2.565

2.  Balancing the normal appendectomy rate with the perforated appendicitis rate: implications for quality assurance.

Authors:  V Velanovich; R Satava
Journal:  Am Surg       Date:  1992-04       Impact factor: 0.688

3.  Has misdiagnosis of appendicitis decreased over time? A population-based analysis.

Authors:  D R Flum; A Morris; T Koepsell; E P Dellinger
Journal:  JAMA       Date:  2001-10-10       Impact factor: 56.272

4.  Pediatric negative appendectomy rate: trend, predictors, and differentials.

Authors:  Tolulope A Oyetunji; Sharon K Ong'uti; Oluwaseyi B Bolorunduro; Edward E Cornwell; Benedict C Nwomeh
Journal:  J Surg Res       Date:  2011-05-19       Impact factor: 2.192

5.  Neurogenic appendicopathy: a clinical disease entity?

Authors:  C Franke; C D Gerharz; H Böhner; C Ohmann; G Heydrich; H J Krämling; W Stock; D Rosen; K Kurpreugsch; H D Röher
Journal:  Int J Colorectal Dis       Date:  2002-05       Impact factor: 2.571

Review 6.  Imaging in appendicitis: a review with special emphasis on the treatment of women.

Authors:  Leigh Neumayer; Anne Kennedy
Journal:  Obstet Gynecol       Date:  2003-12       Impact factor: 7.661

7.  [Neurogenic appendicopathy - an immunocytochemical study].

Authors:  H Höfler; P U Heitz
Journal:  Wien Klin Wochenschr       Date:  1982-11-12       Impact factor: 1.704

8.  Defining the current negative appendectomy rate: for whom is preoperative computed tomography making an impact?

Authors:  Patrick L Wagner; Soumitra R Eachempati; Kevin Soe; Frederic M Pieracci; Jian Shou; Philip S Barie
Journal:  Surgery       Date:  2008-08       Impact factor: 3.982

Review 9.  Optimizing the role of imaging in appendicitis.

Authors:  Andrea S Doria
Journal:  Pediatr Radiol       Date:  2009-04

10.  Routine ultrasound and limited computed tomography for the diagnosis of acute appendicitis.

Authors:  Boudewijn R Toorenvliet; Fraukje Wiersma; Rutger F R Bakker; Jos W S Merkus; Paul J Breslau; Jaap F Hamming
Journal:  World J Surg       Date:  2010-10       Impact factor: 3.352

View more
  4 in total

Review 1.  Neurogenic appendicopathy: an underestimated disease-systematic review of the literature.

Authors:  Sarah Peisl; Oliver Burckhardt; Bernhard Egger
Journal:  Int J Colorectal Dis       Date:  2021-04-10       Impact factor: 2.571

2.  Comparison of clinical outcome of laparoscopic versus open appendectomy for complicated appendicitis.

Authors:  P Horvath; J Lange; R Bachmann; F Struller; A Königsrainer; M Zdichavsky
Journal:  Surg Endosc       Date:  2016-05-18       Impact factor: 4.584

3.  Routine histopathologic examination of appendectomy specimens: retrospective analysis of 1255 patients.

Authors:  Arif Emre; Sami Akbulut; Zehra Bozdag; Mehmet Yilmaz; Murat Kanlioz; Rabia Emre; Nurhan Sahin
Journal:  Int Surg       Date:  2013 Oct-Dec

Review 4.  Neurogenic Appendicitis: A Reappraisal of the Clinicopathological Features and Pathogenesis.

Authors:  Mahmoud Rezk Abdelwahed Hussein; Ali Al Bshabshe; Ahmed Abdelsatar Elhakeem; Mahmoud Kamal Elsamman
Journal:  Diagnostics (Basel)       Date:  2022-06-03
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.