Literature DB >> 23052348

[Renal cancer biomarkers. What is justified?].

H Moch1.   

Abstract

Renal carcinoma biomarkers are of potential interest for the diagnosis of renal tumor subtypes and prediction of prognosis or reponses to targeted therapies. Due to the identification of novel renal tumor subtypes, diagnostic immunohistochemical biomarkers are of increasing importance. However, there is currently not enough clinical evidence to recommend prognostic or predictive biomarkers in routine pathology. Therapeutic decisions are still based on correct tumor classification, tumor differentiation grade, and tumor stage. Recent studies have emphasized the relevance of detailed analysis of hilus fat tissue for a correct pT-category. This review summarizes recent developments in renal cancer biomarker research.

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Year:  2012        PMID： 23052348     DOI： 10.1007/s00292-012-1683-8

Source DB:  PubMed          Journal:  Pathologe        ISSN： 0172-8113            Impact factor:   1.011


  61 in total

1.  Renal chromophobe cell carcinoma and oncocytoma. A comparative morphologic, histochemical, and immunohistochemical study of 124 cases.

Authors:  B Cochand-Priollet; V Molinié; J Bougaran; R Bouvier; M C Dauge-Geffroy; S Deslignières; J C Fournet; P Gros; A Lesourd; J P Saint-André; M Toublanc; A Vieillefond; M Wassef; A Fontaine; L Groleau
Journal:  Arch Pathol Lab Med       Date:  1997-10       Impact factor: 5.534

2.  Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia.

Authors:  Satish K Tickoo; Mariza N dePeralta-Venturina; Lara R Harik; Heath D Worcester; Mohamed E Salama; Andrew N Young; Holger Moch; Mahul B Amin
Journal:  Am J Surg Pathol       Date:  2006-02       Impact factor: 6.394

3.  Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization.

Authors:  H Bissig; J Richter; R Desper; V Meier; P Schraml; A A Schäffer; G Sauter; M J Mihatsch; H Moch
Journal:  Am J Pathol       Date:  1999-07       Impact factor: 4.307

4.  Handling and reporting of nephrectomy specimens for adult renal tumours: a survey by the European Network of Uropathology.

Authors:  Ferran Algaba; Brett Delahunt; Daniel M Berney; Philippe Camparo; Eva Compérat; David Griffiths; Glen Kristiansen; Antonio Lopez-Beltran; Guido Martignoni; Holger Moch; Rodolfo Montironi; Murali Varma; Lars Egevad
Journal:  J Clin Pathol       Date:  2011-09-30       Impact factor: 3.411

5.  Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer.

Authors:  Corinne Dahinden; Barbara Ingold; Peter Wild; Gunther Boysen; Van-Duc Luu; Matteo Montani; Glen Kristiansen; Tullio Sulser; Peter Bühlmann; Holger Moch; Peter Schraml
Journal:  Clin Cancer Res       Date:  2009-12-22       Impact factor: 12.531

6.  Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma.

Authors:  Sakari Vanharanta; Mary Buchta; Sarah R McWhinney; Sanna K Virta; Mariola Peçzkowska; Carl D Morrison; Rainer Lehtonen; Andrzej Januszewicz; Heikki Järvinen; Matti Juhola; Jukka-Pekka Mecklin; Eero Pukkala; Riitta Herva; Maija Kiuru; Nina N Nupponen; Lauri A Aaltonen; Hartmut P H Neumann; Charis Eng
Journal:  Am J Hum Genet       Date:  2003-12-18       Impact factor: 11.025

7.  Tubulocystic carcinoma of the kidney: a new entity among renal tumors.

Authors:  Sandy Azoulay; Annick Vieillefond; François Paraf; Dominique Pasquier; Olivier Cussenot; Patrice Callard; Mathilde Sibony
Journal:  Virchows Arch       Date:  2007-09-05       Impact factor: 4.064

8.  Tubulocystic carcinoma of the kidney: clinicopathologic and molecular characterization.

Authors:  Ximing J Yang; Ming Zhou; Ondrej Hes; Steven Shen; Rongshan Li; Jose Lopez; Rajal B Shah; Yu Yang; Shang-Tian Chuang; Fan Lin; Maria M Tretiakova; Eric J Kort; Bin Tean Teh
Journal:  Am J Surg Pathol       Date:  2008-02       Impact factor: 6.394

Review 9.  Diagnostic and prognostic molecular markers for renal cell carcinoma: a critical appraisal of the current state of research and clinical applicability.

Authors:  Christian Eichelberg; Kerstin Junker; Börje Ljungberg; Holger Moch
Journal:  Eur Urol       Date:  2009-01-13       Impact factor: 20.096

10.  Integrative genome-wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome.

Authors:  Manfred Beleut; Philip Zimmermann; Michael Baudis; Nicole Bruni; Peter Bühlmann; Oliver Laule; Van-Duc Luu; Wilhelm Gruissem; Peter Schraml; Holger Moch
Journal:  BMC Cancer       Date:  2012-07-23       Impact factor: 4.430
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  1 in total

1.  Large (>3.8 cm) clear cell renal cell carcinomas are morphologically and immunohistochemically heterogeneous.

Authors:  Laura Zaldumbide; Asier Erramuzpe; Rosa Guarch; Jesús M Cortés; José I López
Journal:  Virchows Arch       Date:  2014-11-05       Impact factor: 4.064
  1 in total

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