| Literature DB >> 23040363 |
Elana J Bernstein1, Christian Schmidt-Lauber, Jonathan Kay.
Abstract
Nephrogenic systemic fibrosis (NSF) is an iatrogenic fibrosing disorder that primarily affects individuals with chronic kidney disease (CKD) following exposure to gadolinium-based contrast agents (GBCAs) during imaging procedures. NSF is characterised by skin thickening, tethering and hyperpigmentation; flexion contractures of joints; and extracutaneous fibrosis. This article reviews the history, clinical manifestations, epidemiology, histopathology and pathophysiology of this disabling disease.Entities:
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Year: 2012 PMID: 23040363 DOI: 10.1016/j.berh.2012.07.008
Source DB: PubMed Journal: Best Pract Res Clin Rheumatol ISSN: 1521-6942 Impact factor: 4.098