Literature DB >> 23038623

Click and pick: identification of sialoside analogues for siglec-based cell targeting.

Cory D Rillahan1, Erik Schwartz, Ryan McBride, Valery V Fokin, James C Paulson.   

Abstract

Click 'n' chips: Azide and alkyne-bearing sialic acids (purple diamond; see picture) were subjected to high-throughput click chemistry to generate a library of sialic acid analogues. Microarray printing of the library and screening with the siglec family of sialic-acid-binding proteins, led to the identification of high-affinity ligands for siglec-9 and siglec-10.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23038623      PMCID： PMC3480989          DOI： 10.1002/anie.201205831

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  24 in total

1.  Functional groups of sialic acids involved in binding to siglecs (sialoadhesins) deduced from interactions with synthetic analogues.

Authors:  S Kelm; R Brossmer; R Isecke; H J Gross; K Strenge; R Schauer
Journal:  Eur J Biochem       Date:  1998-08-01

2.  High-affinity ligand probes of CD22 overcome the threshold set by cis ligands to allow for binding, endocytosis, and killing of B cells.

Authors:  Brian E Collins; Ola Blixt; Shoufa Han; Bao Duong; Hongyi Li; Jay K Nathan; Nicolai Bovin; James C Paulson
Journal:  J Immunol       Date:  2006-09-01       Impact factor: 5.422

Review 3.  Siglecs and their roles in the immune system.

Authors:  Paul R Crocker; James C Paulson; Ajit Varki
Journal:  Nat Rev Immunol       Date:  2007-04       Impact factor: 53.106

4.  Sialoside analogue arrays for rapid identification of high affinity siglec ligands.

Authors:  Ola Blixt; Shoufa Han; Liang Liao; Ying Zeng; Julia Hoffmann; Satoshi Futakawa; James C Paulson
Journal:  J Am Chem Soc       Date:  2008-05-02       Impact factor: 15.419

5.  On-virus construction of polyvalent glycan ligands for cell-surface receptors.

Authors:  Eiton Kaltgrad; Mary K O'Reilly; Liang Liao; Shoufa Han; James C Paulson; M G Finn
Journal:  J Am Chem Soc       Date:  2008-03-15       Impact factor: 15.419

Review 6.  Siglecs as targets for therapy in immune-cell-mediated disease.

Authors:  Mary K O'Reilly; James C Paulson
Journal:  Trends Pharmacol Sci       Date:  2009-04-07       Impact factor: 14.819

7.  Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein.

Authors:  Ola Blixt; Brian E Collins; Ingrid M van den Nieuwenhof; Paul R Crocker; James C Paulson
Journal:  J Biol Chem       Date:  2003-05-28       Impact factor: 5.157

8.  Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells.

Authors:  Mary K O'Reilly; Brian E Collins; Shoufa Han; Liang Liao; Cory Rillahan; Pavel I Kitov; David R Bundle; James C Paulson
Journal:  J Am Chem Soc       Date:  2008-05-28       Impact factor: 15.419

9.  Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives.

Authors:  Wei Wang; Tianshun Hu; Patrick A Frantom; Tianqing Zheng; Brian Gerwe; David Soriano Del Amo; Sarah Garret; Ronald D Seidel; Peng Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-04       Impact factor: 11.205

10.  The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.

Authors:  Jiquan Q Zhang; Björn Biedermann; Lars Nitschke; Paul R Crocker
Journal:  Eur J Immunol       Date:  2004-04       Impact factor: 5.532
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  29 in total

1.  Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.

Authors:  Seiya Kitamura; Qinheng Zheng; Jordan L Woehl; Angelo Solania; Emily Chen; Nicholas Dillon; Mitchell V Hull; Miyako Kotaniguchi; John R Cappiello; Shinichi Kitamura; Victor Nizet; K Barry Sharpless; Dennis W Wolan
Journal:  J Am Chem Soc       Date:  2020-06-10       Impact factor: 15.419

2.  Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas.

Authors:  Cory D Rillahan; Matthew S Macauley; Erik Schwartz; Yuan He; Ryan McBride; Britni M Arlian; Janani Rangarajan; Valery V Fokin; James C Paulson
Journal:  Chem Sci       Date:  2014-06-01       Impact factor: 9.825

Review 3.  Sialic acid-binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses.

Authors:  Heinz Läubli; Ajit Varki
Journal:  Cell Mol Life Sci       Date:  2019-09-04       Impact factor: 9.261

Review 4.  Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.

Authors:  Takashi Angata; Corwin M Nycholat; Matthew S Macauley
Journal:  Trends Pharmacol Sci       Date:  2015-10       Impact factor: 14.819

5.  The isothiocyanato moiety: an ideal protecting group for the stereoselective synthesis of sialic acid glycosides and subsequent diversification.

Authors:  Appi Reddy Mandhapati; Salla Rajender; Jonathan Shaw; David Crich
Journal:  Angew Chem Int Ed Engl       Date:  2014-11-28       Impact factor: 15.336

6.  A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells.

Authors:  Corwin M Nycholat; Shiteng Duan; Eva Knuplez; Charli Worth; Mila Elich; Anzhi Yao; Jeremy O'Sullivan; Ryan McBride; Yadong Wei; Steve M Fernandes; Zhou Zhu; Ronald L Schnaar; Bruce S Bochner; James C Paulson
Journal:  J Am Chem Soc       Date:  2019-08-30       Impact factor: 15.419

Review 7.  Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation.

Authors:  Bruce S Bochner; Nives Zimmermann
Journal:  J Allergy Clin Immunol       Date:  2015-01-13       Impact factor: 10.793

Review 8.  Glycomaterials for probing host-pathogen interactions and the immune response.

Authors:  Mia L Huang; Christopher J Fisher; Kamil Godula
Journal:  Exp Biol Med (Maywood)       Date:  2016-05-04

9.  Oxidative Deamination of N-Acetyl Neuraminic Acid: Substituent Effects and Mechanism.

Authors:  Szymon Buda; David Crich
Journal:  J Am Chem Soc       Date:  2016-01-15       Impact factor: 15.419

10.  On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7.

Authors:  Cory D Rillahan; Erik Schwartz; Christoph Rademacher; Ryan McBride; Janani Rangarajan; Valery V Fokin; James C Paulson
Journal:  ACS Chem Biol       Date:  2013-04-24       Impact factor: 5.100
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