Literature DB >> 23035174

MIC1-MAG1-SAG1 chimeric protein, a most effective antigen for detection of human toxoplasmosis.

Lucyna Holec-Gasior1, Bartlomiej Ferra, Dorota Drapala.   

Abstract

This study describes a Toxoplasma gondii IgG enzyme-linked immunosorbent assay based on a new chimeric antigen containing three immunodominant regions from the MIC1, MAG1, and SAG1 proteins of the parasite and shows that this test is useful for diagnostic purposes and may replace the lysed and whole-cell antigens.

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Year:  2012        PMID: 23035174      PMCID: PMC3535871          DOI: 10.1128/CVI.00452-12

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN: 1556-679X


  8 in total

1.  Chimeric antigens of Toxoplasma gondii: toward standardization of toxoplasmosis serodiagnosis using recombinant products.

Authors:  Elisa Beghetto; Andrea Spadoni; Luca Bruno; Wilma Buffolano; Nicola Gargano
Journal:  J Clin Microbiol       Date:  2006-06       Impact factor: 5.948

2.  Use of MAG1 recombinant antigen for diagnosis of Toxoplasma gondii infection in humans.

Authors:  Lucyna Holec; Elzbieta Hiszczyńska-Sawicka; Artur Gasior; Anna Brillowska-Dabrowska; Józef Kur
Journal:  Clin Vaccine Immunol       Date:  2007-01-03

3.  A new MIC1-MAG1 recombinant chimeric antigen can be used instead of the Toxoplasma gondii lysate antigen in serodiagnosis of human toxoplasmosis.

Authors:  Lucyna Holec-Gąsior; Bartłomiej Ferra; Dorota Drapała; Dariusz Lautenbach; Józef Kur
Journal:  Clin Vaccine Immunol       Date:  2011-11-23

4.  Immunogenic characterization of the chimeric surface antigen 1 and 2 (SAG1/2) of Toxoplasma gondii expressed in the yeast Pichia pastoris.

Authors:  Yee Ling Lau; Girija Thiruvengadam; Wei Wei Lee; Mun Yik Fong
Journal:  Parasitol Res       Date:  2011-04-01       Impact factor: 2.289

Review 5.  Toxoplasma gondii: from animals to humans.

Authors:  A M Tenter; A R Heckeroth; L M Weiss
Journal:  Int J Parasitol       Date:  2000-11       Impact factor: 3.981

Review 6.  Recombinant proteins in the diagnosis of toxoplasmosis.

Authors:  Dupadahalli Kotresha; Rahmah Noordin
Journal:  APMIS       Date:  2010-08       Impact factor: 3.205

7.  Toxoplasma gondii: enzyme-linked immunosorbent assay using different fragments of recombinant microneme protein 1 (MIC1) for detection of immunoglobulin G antibodies.

Authors:  Lucyna Holec; Artur Gasior; Anna Brillowska-Dabrowska; Józef Kur
Journal:  Exp Parasitol       Date:  2008-01-22       Impact factor: 2.011

8.  High yield expression and single-step purification of Toxoplasma gondii SAG1, GRA1, and GRA7 antigens in Escherichia coli.

Authors:  Elzbieta Hiszczyńska-Sawicka; Anna Brillowska-Dabrowska; Sławomir Dabrowski; Halina Pietkiewicz; Przemysław Myjak; Józef Kur
Journal:  Protein Expr Purif       Date:  2003-01       Impact factor: 1.650

  8 in total
  9 in total

Review 1.  Advances in serological, imaging techniques and molecular diagnosis of Toxoplasma gondii infection.

Authors:  Ali Rostami; Panagiotis Karanis; Shirzad Fallahi
Journal:  Infection       Date:  2018-01-12       Impact factor: 3.553

Review 2.  Toxoplasma gondii recombinant antigens as tools for serodiagnosis of human toxoplasmosis: current status of studies.

Authors:  Lucyna Holec-Gasior
Journal:  Clin Vaccine Immunol       Date:  2013-06-19

3.  A new Toxoplasma gondii chimeric antigen containing fragments of SAG2, GRA1, and ROP1 proteins-impact of immunodominant sequences size on its diagnostic usefulness.

Authors:  Bartłomiej Ferra; Lucyna Holec-Gąsior; Józef Kur
Journal:  Parasitol Res       Date:  2015-06-09       Impact factor: 2.289

Review 4.  Importance of serological cross-reactivity among Toxoplasma gondii, Hammondia spp., Neospora spp., Sarcocystis spp. and Besnoitia besnoiti.

Authors:  Luís F P Gondim; José R Mineo; Gereon Schares
Journal:  Parasitology       Date:  2017-02-28       Impact factor: 3.234

5.  The first study on the usefulness of recombinant tetravalent chimeric proteins containing fragments of SAG2, GRA1, ROP1 and AMA1 antigens in the detection of specific anti-Toxoplasma gondii antibodies in mouse and human sera.

Authors:  Bartłomiej Tomasz Ferra; Lucyna Holec-Gąsior; Justyna Gatkowska; Bożena Dziadek; Katarzyna Dzitko; Weronika Grąźlewska; Dariusz Lautenbach
Journal:  PLoS One       Date:  2019-06-06       Impact factor: 3.240

Review 6.  Review on the Current Trends of Toxoplasmosis Serodiagnosis in Humans.

Authors:  Rochelle Haidee D Ybañez; Adrian P Ybañez; Yoshifumi Nishikawa
Journal:  Front Cell Infect Microbiol       Date:  2020-05-08       Impact factor: 5.293

Review 7.  Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals.

Authors:  Amjad Hayat Khan; Rahmah Noordin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2019-08-20       Impact factor: 3.267

8.  Toxoplasma gondii Tetravalent Chimeric Proteins as Novel Antigens for Detection of Specific Immunoglobulin G in Sera of Small Ruminants.

Authors:  Lucyna Holec-Gąsior; Bartłomiej Ferra; Weronika Grąźlewska
Journal:  Animals (Basel)       Date:  2019-12-13       Impact factor: 2.752

9.  Borrelia burgdorferi BmpA-BBK32 and BmpA-BBA64: New Recombinant Chimeric Proteins with Potential Diagnostic Value.

Authors:  Weronika Grąźlewska; Bartłomiej Ferra; Monika Rudzińska; Lucyna Holec-Gąsior
Journal:  Pathogens       Date:  2021-06-18
  9 in total

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