William V Giannobile1. 1. Department of Periodontics and Oral Medicine, Michigan Center for Oral Health Research, School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, Mic 48109-1078, USA. william.giannobile@umich.edu
Abstract
BACKGROUND: and Overview The use of salivary diagnostics continues to develop and advance the field of risk determination for periodontal diseases. Researchers are investigating genetic, microbial and protein biomarkers with the objective of translating findings to such aspects of clinical care as broad patient screening, monitoring and treatment planning. METHODS: /st> In this review, the author briefly explores currently available salivary diagnostics used to identify bacteria prevalent in periodontal disease, and focuses on the future development and use of a variety of rapid disease detection platforms, such as lab-on-a-chip, as a point-of-care device for identification of patients' risk. CONCLUSIONS: and CLINICAL IMPLICATIONS: /st> Several diagnostic tests are commercially available, and point-of-care tests are under development. However, challenges remain regarding the introduction of these technologies to clinical practice and adoption by dental practitioners for promotion of personalized oral health care.
BACKGROUND: and Overview The use of salivary diagnostics continues to develop and advance the field of risk determination for periodontal diseases. Researchers are investigating genetic, microbial and protein biomarkers with the objective of translating findings to such aspects of clinical care as broad patient screening, monitoring and treatment planning. METHODS: /st> In this review, the author briefly explores currently available salivary diagnostics used to identify bacteria prevalent in periodontal disease, and focuses on the future development and use of a variety of rapid disease detection platforms, such as lab-on-a-chip, as a point-of-care device for identification of patients' risk. CONCLUSIONS: and CLINICAL IMPLICATIONS: /st> Several diagnostic tests are commercially available, and point-of-care tests are under development. However, challenges remain regarding the introduction of these technologies to clinical practice and adoption by dental practitioners for promotion of personalized oral health care.
Authors: J L Ebersole; R J Kryscio; C Campbell; D F Kinane; J McDevitt; N Christodoulides; P N Floriano; C S Miller Journal: J Periodontal Res Date: 2016-08-23 Impact factor: 4.419
Authors: Karolina E Kaczor-Urbanowicz; Harsh M Trivedi; Patricia O Lima; Paulo M Camargo; William V Giannobile; Tristan R Grogan; Frederico O Gleber-Netto; Yair Whiteman; Feng Li; Hyo Jung Lee; Karan Dharia; Katri Aro; Carmen Martin Carreras-Presas; Saarah Amuthan; Manjiri Vartak; David Akin; Hiba Al-Adbullah; Kanika Bembey; Perry R Klokkevold; David Elashoff; Virginia M Barnes; Rose Richter; William DeVizio; James G Masters; David T W Wong Journal: J Clin Periodontol Date: 2018-06-15 Impact factor: 8.728
Authors: Erica N Recker; Kim A Brogden; Gustavo Avila-Ortiz; Carol L Fischer; Keyla Pagan-Rivera; Deborah V Dawson; Katherine M Smith; Satheesh Elangovan Journal: Arch Oral Biol Date: 2015-07-14 Impact factor: 2.633