OBJECTIVES: To elucidate whether fluorine-18-labeled ((18)F) fluoro-2-deoxy-d-glucose (FDG) accumulation can reflect the extent of periodontal inflammation, periapical inflammation, or dental caries. STUDY DESIGN: (18)F-FDG accumulations on positron emission tomography (PET)-computed tomography (CT) were retrospectively compared with the size of the bone resorption areas caused by periodontal inflammation, periapical inflammation, or dental caries on panoramic radiographs, CT, and magnetic resonance imaging (MRI) in 44 subjects. RESULTS: A significant correlation was found between the size of the bone resorption area caused by periodontal (r = 0.595, P < .01) or periapical (r = 0.560, P < .01) inflammation and the highest standardized uptake value (SUVmax) of (18)F-FDG accumulation. A significant correlation was found between the periodontal (r = 0.622, P < .01) or periapical (r = 0.394, P < .01) inflammatory findings on MRI and the SUVmax of (18)F-FDG accumulation. The SUVmax of (18)F-FDG around most teeth with caries was under 1.5. CONCLUSIONS: (18)F-FDG accumulation reflects the extent of dental inflammation, not dental caries.
OBJECTIVES: To elucidate whether fluorine-18-labeled ((18)F) fluoro-2-deoxy-d-glucose (FDG) accumulation can reflect the extent of periodontal inflammation, periapical inflammation, or dental caries. STUDY DESIGN: (18)F-FDG accumulations on positron emission tomography (PET)-computed tomography (CT) were retrospectively compared with the size of the bone resorption areas caused by periodontal inflammation, periapical inflammation, or dental caries on panoramic radiographs, CT, and magnetic resonance imaging (MRI) in 44 subjects. RESULTS: A significant correlation was found between the size of the bone resorption area caused by periodontal (r = 0.595, P < .01) or periapical (r = 0.560, P < .01) inflammation and the highest standardized uptake value (SUVmax) of (18)F-FDG accumulation. A significant correlation was found between the periodontal (r = 0.622, P < .01) or periapical (r = 0.394, P < .01) inflammatory findings on MRI and the SUVmax of (18)F-FDG accumulation. The SUVmax of (18)F-FDG around most teeth with caries was under 1.5. CONCLUSIONS: (18)F-FDG accumulation reflects the extent of dental inflammation, not dental caries.
Authors: Amorina Ishai; Michael T Osborne; Karim El Kholy; Richard A P Takx; Abdelrahman Ali; Neal Yuan; Priscilla Hsue; Thomas E Van Dyke; Ahmed Tawakol Journal: JACC Cardiovasc Imaging Date: 2019-07-17
Authors: S Kito; H Koga; M Kodama; M Habu; S Kokuryo; N Yamamoto; M Oda; T Nishino; M Zhang; K Matsuo; N Wakasugi-Sato; S Matsumoto-Takeda; Y Seta; D Yoshiga; T Kaneuji; S Nogami; I Yoshioka; Y Yamashita; T Tanaka; I Miyamoto; C Kitamura; K Tominaga; Y Morimoto Journal: Dentomaxillofac Radiol Date: 2013-04-22 Impact factor: 2.419
Authors: Thomas E Van Dyke; Karim El Kholy; Amorina Ishai; Richard A P Takx; Kene Mezue; Shady M Abohashem; Abdelrahman Ali; Neal Yuan; Priscilla Hsue; Michael T Osborne; Ahmed Tawakol Journal: J Periodontol Date: 2021-02-13 Impact factor: 6.993
Authors: Sharath Subramanian; Hamed Emami; Esad Vucic; Parmanand Singh; Jayanthi Vijayakumar; Kenneth M Fifer; Achilles Alon; Sudha S Shankar; Michael Farkouh; James H F Rudd; Zahi A Fayad; Thomas E Van Dyke; Ahmed Tawakol Journal: J Am Coll Cardiol Date: 2013-09-24 Impact factor: 24.094
Authors: S Kito; H Koga; M Kodama; M Habu; S Kokuryo; M Oda; K Matsuo; T Nishino; S Matsumoto-Takeda; M Uehara; D Yoshiga; T Tanaka; S Nishimura; I Miyamoto; M Sasaguri; K Tominaga; I Yoshioka; Y Morimoto Journal: Med Oral Patol Oral Cir Bucal Date: 2016-05-01