Literature DB >> 23020279

Guadial A and psiguadials C and D, three unusual meroterpenoids from Psidium guajava.

Meng Shao1, Ying Wang, Yu-Qing Jian, Xiao-Jun Huang, Dong-Mei Zhang, Qing-Fa Tang, Ren-Wang Jiang, Xue-Gang Sun, Zhi-Ping Lv, Xiao-Qi Zhang, Wen-Cai Ye.   

Abstract

The first monoterpene-based meroterpenoid (1) and two novel sesquiterpene-based ones (2 and 3) with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures with absolute configuration were elucidated by extensive spectroscopic studies. A plausible biosynthetic pathway for all meroterpenoids from the title plant is also proposed. Compounds 2 and 3 showed significant cytotoxicity toward HepG2 and HepG2/ADM cells.

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Year:  2012        PMID： 23020279     DOI： 10.1021/ol302423b

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

Review 1.  Recent advances in the synthesis of gem-dimethylcyclobutane natural products.

Authors:  Erin N Hancock; Johannes M Wiest; M Kevin Brown
Journal:  Nat Prod Rep       Date:  2019-10-16       Impact factor: 13.423

Review 2.  Biological activities of meroterpenoids isolated from different sources.

Authors:  Neeraj Kumar Fuloria; Radhika K Raheja; Kaushal H Shah; Manisha J Oza; Yogesh A Kulkarni; Vetriselvan Subramaniyan; Mahendran Sekar; Shivkanya Fuloria
Journal:  Front Pharmacol       Date:  2022-09-19       Impact factor: 5.988

3.  Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B.

Authors:  Lauren M Chapman; Jordan C Beck; Caitlin R Lacker; Linglin Wu; Sarah E Reisman
Journal:  J Org Chem       Date:  2018-05-18       Impact factor: 4.354

Review 4.  Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis.

Authors:  Trevor N Purdy; Bradley S Moore; April L Lukowski
Journal:  J Nat Prod       Date:  2022-02-02       Impact factor: 4.803

5.  Preparative isolation and purification of five flavonoid glycosides and one benzophenone galloyl glycoside from Psidium guajava by high-speed counter-current chromatography (HSCCC).

Authors:  Yindi Zhu; Yue Liu; Ying Zhan; Lin Liu; Yajuan Xu; Tunhai Xu; Tonghua Liu
Journal:  Molecules       Date:  2013-12-16       Impact factor: 4.411

6.  Ozone and Wounding Stresses Differently Alter the Temporal Variation in Formylated Phloroglucinols in Eucalyptus globulus Leaves.

Authors:  Bin Liu; Bruna Marques Dos Santos; Arooran Kanagendran; Elizabeth H Jakobsen Neilson; Ülo Niinemets
Journal:  Metabolites       Date:  2019-03-06

7.  Quantification and Localization of Formylated Phloroglucinol Compounds (FPCs) in Eucalyptus Species.

Authors:  Bruna Marques Dos Santos; Juliane F S Zibrandtsen; Disan Gunbilig; Mette Sørensen; Federico Cozzi; Berin A Boughton; Allison Maree Heskes; Elizabeth Heather Jakobsen Neilson
Journal:  Front Plant Sci       Date:  2019-02-26       Impact factor: 5.753

8.  Two New Flavonoids from the Nuts of Areca catechu.

Authors:  Mengfei Yuan; Yunlin Ao; Nan Yao; Jing Xie; Dongmei Zhang; Jian Zhang; Xiaoqi Zhang; Wencai Ye
Journal:  Molecules       Date:  2019-08-07       Impact factor: 4.411

9.  Simultaneous Determination of α-Glucosidase Inhibitory Triterpenoids in Psidium guajava Using HPLC-DAD-ELSD and Pressurized Liquid Extraction.

Authors:  In-Cheng Chao; Ying Chen; Mei-Hua Gao; Li-Gen Lin; Xiao-Qi Zhang; Wen-Cai Ye; Qing-Wen Zhang
Journal:  Molecules       Date:  2020-03-11       Impact factor: 4.411

10.  Psiguajadials A-K: Unusual Psidium Meroterpenoids as Phosphodiesterase-4 Inhibitors from the Leaves of Psidium guajava.

Authors:  Gui-Hua Tang; Zhen Dong; Yan-Qiong Guo; Zhong-Bin Cheng; Chu-Jun Zhou; Sheng Yin
Journal:  Sci Rep       Date:  2017-04-21       Impact factor: 4.379
  10 in total

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