Literature DB >> 23011892

Reactive tonsillar enlargement showing strong 18F-FDG uptake during the follow-up of follicular lymphoma.

Patricia do Socorro Queiroz Feio1, Camilla Borges Ferreira Gomes, Alexandre Simões Nogueira, Luciana Yamamoto Almeida, José Vassallo, Fernando Augusto Soares, Oslei Paes Almeida, Jorge Esquiche León.   

Abstract

The 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a standard procedure for the diagnosis, staging, and restaging in lymphoma patients. However, a relative high rate of false-positive results has been reported. We report a case of a 40-year-old man with a previous history of a nodal follicular lymphoma, stage IVA, treated with R-CHOP, which showed strong 18F-FDG uptake in the Waldeyer's tonsillar ring during his follow-up, being considered highly suspicious of relapsed lymphoma. A surgical removal of the palatine tonsils and adenoids was performed, which showed reactive follicular hyperplasia. Furthermore, bone marrow biopsy revealed absence of neoplasia. The patient is still in follow-up with no signs of recurrent lymphoma. This case illustrates that, despite the high sensitivity for the detection of recurrent lymphoma, 18F-FDG uptake should be interpreted with great caution and confirmatory studies should be performed before any therapy.

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Year:  2012        PMID: 23011892      PMCID: PMC3738754          DOI: 10.1007/s12105-012-0400-5

Source DB:  PubMed          Journal:  Head Neck Pathol        ISSN: 1936-055X


  23 in total

1.  Reactive lymphoid hyperplasia with giant follicles associated with post-therapeutic state of hematological malignancies: a report of six cases.

Authors:  Masaru Kojima; Kayoko Murayama; Keiko Higuchi; Morio Matsumoto; Yoshio Tamaki; Nobuhide Masawa
Journal:  Leuk Lymphoma       Date:  2006-07

2.  Utility of 18F-FDG PET/CT uptake patterns in Waldeyer's ring for differentiating benign from malignant lesions in lateral pharyngeal recess of nasopharynx.

Authors:  Yen-Kung Chen; Chen-Tau Su; Kwan-Hwa Chi; Ru-Hwa Cheng; Su-Chen Wang; Chung-Huei Hsu
Journal:  J Nucl Med       Date:  2007-01       Impact factor: 10.057

3.  Interesting image. FDG-PET/CT in primary large B-cell lymphoma of the hard palate.

Authors:  Dimitrios Kalkanis; Maria Kalkani; Hilton Gomes; Fabio Paes; Panagiotis Sideras; George N Sfakianakis
Journal:  Clin Nucl Med       Date:  2010-01       Impact factor: 7.794

4.  Whole-body positron emission tomography using 18F-fluorodeoxyglucose for posttreatment evaluation in Hodgkin's disease and non-Hodgkin's lymphoma has higher diagnostic and prognostic value than classical computed tomography scan imaging.

Authors:  G Jerusalem; Y Beguin; M F Fassotte; F Najjar; P Paulus; P Rigo; G Fillet
Journal:  Blood       Date:  1999-07-15       Impact factor: 22.113

5.  Mantle cell lymphoma presenting with a tumor of the hard palate.

Authors:  Chika Kyo; Yumi Kawaoka; Koji Kinoshita; Hitoshi Ohno
Journal:  Intern Med       Date:  2010-08-02       Impact factor: 1.271

6.  Normal FDG distribution patterns in the head and neck: PET/CT evaluation.

Authors:  Yuji Nakamoto; Mitsuaki Tatsumi; Dima Hammoud; Christian Cohade; Medhat M Osman; Richard L Wahl
Journal:  Radiology       Date:  2005-03       Impact factor: 11.105

7.  18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG-PET) visualizes follicular lymphoma irrespective of grading.

Authors:  S Wöhrer; U Jaeger; K Kletter; A Becherer; A Hauswirth; K Turetschek; M Raderer; M Hoffmann
Journal:  Ann Oncol       Date:  2006-02-23       Impact factor: 32.976

8.  Overexpression of Glut1 in lymphoid follicles correlates with false-positive (18)F-FDG PET results in lung cancer staging.

Authors:  Jin-Haeng Chung; Kyung-Ja Cho; Seung-Sook Lee; Hee Jong Baek; Jong-Ho Park; Gi Jeong Cheon; Chang-Woon Choi; Sang Moo Lim
Journal:  J Nucl Med       Date:  2004-06       Impact factor: 10.057

9.  Increased (18)F-fluorodeoxyglucose uptake in benign, nonphysiologic lesions found on whole-body positron emission tomography/computed tomography (PET/CT): accumulated data from four years of experience with PET/CT.

Authors:  Ur Metser; Einat Even-Sapir
Journal:  Semin Nucl Med       Date:  2007-05       Impact factor: 4.446

10.  Causes and imaging features of false positives and false negatives on F-PET/CT in oncologic imaging.

Authors:  Niamh M Long; Clare S Smith
Journal:  Insights Imaging       Date:  2011-09-09
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  3 in total

1.  Rebound adenoid hyperplasia after chemotherapy in pediatric patients with head and neck lymphoma: MR imaging findings.

Authors:  Hiroki Kato; Masayuki Matsuo; Michio Ozeki; Toshiyuki Fukao
Journal:  Jpn J Radiol       Date:  2016-07-19       Impact factor: 2.374

2.  18FDG-PET/CT Specificity for the Detection of Lymphoma Recurrence in the Tonsils.

Authors:  Jonathan D West; Mary E Kim; Dorian M Lapalma; Maria Vergara-Lluri; Peter Conti; Tamara N Chambers; Mark S Swanson
Journal:  OTO Open       Date:  2021-11-15

3.  Thyroid Gland 18F-FDG Uptake in Neurofibromatosis Type 1.

Authors:  Zoë Y G J van Lierop; Sander Jentjens; Monique H M E Anten; Roel Wierts; Connie T Stumpel; Bas Havekes; Marinus J P G van Kroonenburgh
Journal:  Eur Thyroid J       Date:  2018-06-05
  3 in total

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