Literature DB >> 23001265

Treponema pallidum azithromycin resistance in Dublin, Ireland.

Eavan G Muldoon1, Anne Walsh, Brendan Crowley, Fiona Mulcahy.   

Abstract

This study aimed to reassess rates of syphilis azithromycin resistance in Dublin. Of the 104 samples, 36 (34.6%) were positive for Treponema pallidum DNA by polymerase chain reaction. Thirty samples were analyzed for A2058G mutation, 29 samples sequenced. Of the 29 samples, 27 (93.1%) had the mutation. Azithromycin cannot be recommended for the treatment of syphilis in Dublin.

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Year:  2012        PMID: 23001265     DOI: 10.1097/OLQ.0b013e318269995f

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN: 0148-5717            Impact factor:   2.830


  15 in total

1.  Two mutations associated with macrolide resistance in Treponema pallidum in Shandong, China.

Authors:  Zhen Li; Jianling Hou; Rongtao Zheng; Zhongwei Li; Jing Wen; Dianchang Liu; Ruyuan Liu; Tongsheng Chu; Bing Liu; Gongqi Yu; Hongqing Tian; Furen Zhang
Journal:  J Clin Microbiol       Date:  2013-09-18       Impact factor: 5.948

2.  Molecular typing of Treponema pallidum in the Czech Republic during 2011 to 2013: increased prevalence of identified genotypes and of isolates with macrolide resistance.

Authors:  Linda Grillová; Helena Pĕtrošová; Lenka Mikalová; Radim Strnadel; Eliška Dastychová; Ivana Kuklová; Martina Kojanová; Miluše Kreidlová; Daniela Vaňousová; Jana Hercogová; Přemysl Procházka; Hana Zákoucká; Alena Krchňáková; Vladimír Vašků; David Šmajs
Journal:  J Clin Microbiol       Date:  2014-08-06       Impact factor: 5.948

3.  Detection of the A2058G and A2059G 23S rRNA gene point mutations associated with azithromycin resistance in Treponema pallidum by use of a TaqMan real-time multiplex PCR assay.

Authors:  Cheng-Yen Chen; Kai-Hua Chi; Allan Pillay; Eli Nachamkin; John R Su; Ronald C Ballard
Journal:  J Clin Microbiol       Date:  2013-01-02       Impact factor: 5.948

4.  Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains?

Authors:  David Šmajs; Lenka Paštěková; Linda Grillová
Journal:  Am J Trop Med Hyg       Date:  2015-07-27       Impact factor: 2.345

5.  An Update on the Global Epidemiology of Syphilis.

Authors:  Noah Kojima; Jeffrey D Klausner
Journal:  Curr Epidemiol Rep       Date:  2018-02-19

Review 6.  Syphilis: antibiotic treatment and resistance.

Authors:  L V Stamm
Journal:  Epidemiol Infect       Date:  2014-10-31       Impact factor: 4.434

Review 7.  Mechanism of action, resistance, synergism, and clinical implications of azithromycin.

Authors:  Mohsen Heidary; Ahmad Ebrahimi Samangani; Abolfazl Kargari; Aliakbar Kiani Nejad; Ilya Yashmi; Moloudsadat Motahar; Elahe Taki; Saeed Khoshnood
Journal:  J Clin Lab Anal       Date:  2022-04-21       Impact factor: 3.124

8.  Molecular typing of Treponema pallidum isolates from Buenos Aires, Argentina: Frequent Nichols-like isolates and low levels of macrolide resistance.

Authors:  Lucía Gallo Vaulet; Linda Grillová; Lenka Mikalová; Ricardo Casco; Marcelo Rodríguez Fermepin; María A Pando; David Šmajs
Journal:  PLoS One       Date:  2017-02-24       Impact factor: 3.240

Review 9.  On the pathway to better birth outcomes? A systematic review of azithromycin and curable sexually transmitted infections.

Authors:  R Matthew Chico; Berkin B Hack; Melanie J Newport; Enesia Ngulube; Daniel Chandramohan
Journal:  Expert Rev Anti Infect Ther       Date:  2013-11-06       Impact factor: 5.091

10.  Jarisch-Herxheimer reaction among HIV-positive patients with early syphilis: azithromycin versus benzathine penicillin G therapy.

Authors:  Mao-Song Tsai; Chia-Jui Yang; Nan-Yao Lee; Szu-Min Hsieh; Yu-Hui Lin; Hsin-Yun Sun; Wang-Huei Sheng; Kuan-Yeh Lee; Shan-Ping Yang; Wen-Chun Liu; Pei-Ying Wu; Wen-Chien Ko; Chien-Ching Hung
Journal:  J Int AIDS Soc       Date:  2014-08-28       Impact factor: 5.396

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