Literature DB >> 22997423

Genome sequence of a novel HIV-1 circulating recombinant form 54_01B from Malaysia.

Kim Tien Ng1, Lai Yee Ong, Yutaka Takebe, Adeeba Kamarulzaman, Kok Keng Tee.   

Abstract

We report here the first novel HIV-1 circulating recombinant form (CRF) 54_01B (CRF54_01B) isolated from three epidemiologically unlinked subjects of different risk groups in Malaysia. These recently sampled recombinants showed a complex genome organization composed of parental subtype B' and CRF01_AE, with identical recombination breakpoints observed in the gag, pol, and vif genes. Such a discovery highlights the ongoing active generation and spread of intersubtype recombinants involving the subtype B' and CRF01_AE lineages and indicates the potential of the new CRF in bridging HIV-1 transmission among different risk groups in Southeast Asia.

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Year:  2012        PMID： 22997423      PMCID： PMC3457179          DOI： 10.1128/JVI.01949-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  8 in total

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6.  Continuous crossover(s) events of HIV-1 CRF01_AE and B subtype strains in Malaysia: evidence of rapid and extensive HIV-1 evolution in the region.

Authors:  Katherine A Lau; Bin Wang; Adeeba Kamarulzaman; Kee-Peng Ngb; Nitin K Saksena
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Authors:  Hendrik Streeck; Bin Li; Art F Y Poon; Arne Schneidewind; Adrianne D Gladden; Karen A Power; Demetre Daskalakis; Suzane Bazner; Rosario Zuniga; Christian Brander; Eric S Rosenberg; Simon D W Frost; Marcus Altfeld; Todd M Allen
Journal:  J Exp Med       Date:  2008-07-14       Impact factor: 14.307
  8 in total
  17 in total

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Journal:  AIDS Res Hum Retroviruses       Date:  2015-11-16       Impact factor: 2.205

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5.  Genome Sequences of a Novel HIV-1 Circulating Recombinant Form (CRF59_01B) Identified among Men Who Have Sex with Men in Northeastern China.

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6.  Genetic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF74_01B) Identified among Intravenous Drug Users in Malaysia: Recombination History and Phylogenetic Linkage with Previously Defined Recombinant Lineages.

Authors:  Hui Ting Cheong; Wei Zhen Chow; Yutaka Takebe; Jack Bee Chook; Kok Gan Chan; Haider Abdulrazzaq Abed Al-Darraji; Clayton Koh; Adeeba Kamarulzaman; Kok Keng Tee
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7.  Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants.

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8.  Prevalence of human immunodeficiency virus 1 infection in the last decade among entry travelers in Yunnan Province, China.

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9.  Genome Sequences of a Novel HIV-1 Circulating Recombinant Form, CRF55_01B, Identified in China.

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10.  Genome Sequence of Complex HIV-1 Unique Recombinant Forms Sharing a Common Recombination Breakpoint Identified in Malaysia.

Authors:  Hui Ting Cheong; Kim Tien Ng; Lai Yee Ong; Yutaka Takebe; Kok Gan Chan; Clayton Koh; Haider Abdulrazzaq Abed Al-Darraji; Adeeba Kamarulzaman; Kok Keng Tee
Journal:  Genome Announc       Date:  2015-11-05
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