Validation of the 12-item stroke-specific quality of life scale in a biethnic stroke population.

The 12-item Stroke-Specific Quality of Life Scale (SSQOL), a shortened version of the original SSQOL, was developed to be an efficient and valid outcome in stroke research. We aimed to assess the validity of this scale in a biethnic ischemic stroke population. Patients with validated ischemic stroke who completed the original 49-item SSQOL at 90 days poststroke were identified from a population-based study, the Brain Attack Surveillance in Corpus Christi Project. Cronbach's α was used to assess the internal consistency of the scales. Intraclass correlation coefficients and linear regression were used to assess agreement between the 2 scales. The study cohort comprised 45 patients with ischemic stroke, 56% female and 51% Mexican American, with a mean age of 66.0±11.3 years. The mean score for the 49-item scale was 3.33±0.84, compared with 3.31±0.95 for the 12-item scale. Internal consistency was 0.96 for the 49-item scale and 0.88 for the 12-item scale. The 2 scales were highly correlated (intraclass correlation coefficient, 0.98; R2=0.97). This study in patients with ischemic stroke from diverse racial/ethnic backgrounds found that the more efficient 12-item SSQOL is a valid alternative to the full 49-item SSQOL for the assessment of health-related quality of life.