Sir,We thank Colin et al. for their interest in the publication and are grateful for their constructive and encouraging comments.Their comment on necessity to identify the factors affecting patient's cooperation during surgery under topical anaesthesia is agreed upon by us as well. Pain perception during the surgery is one of the factors which can affect the patient's cooperation during surgery under local anaesthesia. As stated in our article[1] pain perception, reporting and tolerance are variable among individuals and besides other factors gender is also one of them. However, there are contradictory reports regarding relation between gender and pain perception, reporting and tolerance as highlighted by the studies mentioned in the communication received from Colin et al.[23]As mentioned in the communication the average pain score as reported by the patients was more in the female group when compared to the male counterparts but was not statistically significant. We agree that a larger sample size may provide relatively stronger conclusive evidence, but it will be premature to say whether this will prove if the pain perception is different among the two genders. Nevertheless a larger study is warranted for a definite answer.We congratulate Colin et al. for their observation and raising the research question regarding the possibility of gender based differences in pain perception and reporting among patients having significant pain during cataract surgery under topical anaesthesia.