BACKGROUND: Lung transplantation provides a viable option for survival of end-stage respiratory disease. In addition to prolonging survival, there is considerable interest in improving patient-related outcomes such as transplant recipients' symptom experiences. METHODS: A prospective, repeated measures design was used to describe the symptom experience of 85 lung transplant recipients between 2000 and 2005. The transplant symptom inventory was administered before and at one, three, six, nine, and 12 months post-transplant. Ridit analysis provided a unique method for describing symptom experiences and changes. RESULTS: After lung transplantation, significant (p<0.05) improvements were reported for the most frequently occurring and most distressing pre-transplant symptoms (e.g., shortness of breath with activity). Marked increases in the frequency and distress of new symptoms such as tremors were also reported. Patterns of symptom frequency and distress varied with time since transplant. CONCLUSION: The findings provide data-based information that can be used to inform pre- and post-transplant patient education and also help caregivers anticipate a general time frame for symptom changes to prevent or minimize symptoms and their associated distress. In addition, symptoms are described, using an innovative method of illustration which shows "at-a-glance" change or lack of change in patients' symptoms from pre- to post-lung transplant.
BACKGROUND: Lung transplantation provides a viable option for survival of end-stage respiratory disease. In addition to prolonging survival, there is considerable interest in improving patient-related outcomes such as transplant recipients' symptom experiences. METHODS: A prospective, repeated measures design was used to describe the symptom experience of 85 lung transplant recipients between 2000 and 2005. The transplant symptom inventory was administered before and at one, three, six, nine, and 12 months post-transplant. Ridit analysis provided a unique method for describing symptom experiences and changes. RESULTS: After lung transplantation, significant (p<0.05) improvements were reported for the most frequently occurring and most distressing pre-transplant symptoms (e.g., shortness of breath with activity). Marked increases in the frequency and distress of new symptoms such as tremors were also reported. Patterns of symptom frequency and distress varied with time since transplant. CONCLUSION: The findings provide data-based information that can be used to inform pre- and post-transplant patient education and also help caregivers anticipate a general time frame for symptom changes to prevent or minimize symptoms and their associated distress. In addition, symptoms are described, using an innovative method of illustration which shows "at-a-glance" change or lack of change in patients' symptoms from pre- to post-lung transplant.
Authors: C Gutierrez; S Al-Faifi; C Chaparro; T Waddell; D Hadjiliadis; L Singer; S Keshavjee; M Hutcheon Journal: Am J Transplant Date: 2007-05 Impact factor: 8.086
Authors: A Jalowiec; K L Grady; C White-Williams; S Fazekas; M Laff; V Davidson-Bell; E Kracht; W Willson Journal: J Heart Lung Transplant Date: 1997-06 Impact factor: 10.247
Authors: R K Portenoy; H T Thaler; A B Kornblith; J M Lepore; H Friedlander-Klar; E Kiyasu; K Sobel; N Coyle; N Kemeny; L Norton Journal: Eur J Cancer Date: 1994 Impact factor: 9.162
Authors: J P Singer; P P Katz; A Soong; P Shrestha; D Huang; J Ho; M Mindo; J R Greenland; S R Hays; J Golden; J Kukreja; M E Kleinhenz; R J Shah; P D Blanc Journal: Am J Transplant Date: 2017-01-03 Impact factor: 8.086
Authors: Jonathan Paul Singer; Joan Chen; Patricia P Katz; Paul David Blanc; Marjorie Kagawa-Singer; Anita L Stewart Journal: Qual Life Res Date: 2014-12-04 Impact factor: 4.147
Authors: Jonathan P Singer; Allison Soong; Joan Chen; Pavan Shrestha; Hanjing Zhuo; Ying Gao; John R Greenland; Steven R Hays; Jasleen Kukreja; Jeffrey Golden; Steven E Gregorich; Anita L Stewart Journal: Am J Respir Crit Care Med Date: 2019-04-15 Impact factor: 21.405
Authors: Berta Saez-Gimenez; Miriam Barrecheguren; Maria Antònia Ramon; Alba Gomez-Garrido; Carlos Bravo; Víctor Monforte; Manuel López-Meseguer; Cristina Berastegui; Eva Revilla; Christian Romero; Rosalía Laporta; Sonia Fernández-Rozas; Javier Redel-Montero; Amparo Solé; Mercedes de la Torre; Luis Puente; Antonio Roman; Susana Gómez-Ollés; Iñigo Ojanguren Journal: ERJ Open Res Date: 2021-02-01