Literature DB >> 22986705

Influenza A/H1N1 vaccination response is inadequate in down syndrome children when the latest cut-off values are used.

Maaike A Kusters1, Vinus L A Bok, W E A Bolz, E G W Huijskens, M F Peeters, Esther de Vries.   

Abstract

We determined the response of 48 Down syndrome children to 2 doses of influenza A/H1N1 vaccination. Ninety-two percent of the children reached the previously defined protective level (hemagglutination-inhibition titer ≥1:40), but only 27% of the children reached the level of ≥1:110 which was recently described to predict the conventional 50% clinical protection rate in children. Further studies, and potentially adaptations of the schedule, are needed.

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Year:  2012        PMID: 22986705     DOI: 10.1097/INF.0b013e3182737410

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  8 in total

1.  Clinical characteristics and comorbidities of COVID-19 in unvaccinated patients with Down syndrome: first year report in Brazil.

Authors:  Matheus Negri Boschiero; Camila Vantini Capasso Palamim; Fernando Augusto Lima Marson; Manoela Marques Ortega
Journal:  Hum Genet       Date:  2022-06-28       Impact factor: 5.881

2.  COVID-19 Vaccination of Individuals with Down Syndrome-Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated.

Authors:  Anke Hüls; Patrick T Feany; Sophia Isabella Zisman; Alberto C S Costa; Mara Dierssen; Robert Balogh; Stefania Bargagna; Nicole T Baumer; Ana Claudia Brandão; Angelo Carfi; Brian Allen Chicoine; Sujay Ghosh; Monica Lakhanpaul; Johannes Levin; Yona Lunsky; Coral Manso; Eitan Okun; Diego Real de Asua; Anne-Sophie Rebillat; Tilman R Rohrer; Giuseppina Sgandurra; Diletta Valentini; Stephanie L Sherman; Andre Strydom
Journal:  Vaccines (Basel)       Date:  2022-03-29

3.  Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome.

Authors:  Rita Carsetti; Diletta Valentini; Valentina Marcellini; Marco Scarsella; Emiliano Marasco; Ferruccio Giustini; Andrea Bartuli; Alberto Villani; Alberto G Ugazio
Journal:  Eur J Immunol       Date:  2014-12-28       Impact factor: 5.532

4.  Altered endotoxin responsiveness in healthy children with Down syndrome.

Authors:  Dean Huggard; Fiona McGrane; Niamh Lagan; Edna Roche; Joanne Balfe; Timothy Ronan Leahy; Orla Franklin; Ana Moreno; Ashanty M Melo; Derek G Doherty; Eleanor J Molloy
Journal:  BMC Immunol       Date:  2018-11-03       Impact factor: 3.615

5.  Infection risk among adults with down syndrome: a two group series of 101 patients in a tertiary center.

Authors:  Aurélien Guffroy; Yannick Dieudonné; Beatrice Uring-Lambert; Joelle Goetz; Yves Alembik; Anne-Sophie Korganow
Journal:  Orphanet J Rare Dis       Date:  2019-01-11       Impact factor: 4.123

Review 6.  Down syndrome, accelerated aging and immunosenescence.

Authors:  Noémie Gensous; Maria Giulia Bacalini; Claudio Franceschi; Paolo Garagnani
Journal:  Semin Immunopathol       Date:  2020-07-23       Impact factor: 9.623

7.  Safety and Long-Term Immunogenicity of BNT162b2 Vaccine in Individuals with Down Syndrome.

Authors:  Diletta Valentini; Nicola Cotugno; Vittorio Scoppola; Chiara Di Camillo; Luna Colagrossi; Emma Concetta Manno; Carlo Federico Perno; Cristina Russo; Paolo Palma; Paolo Rossi; Alberto Villani
Journal:  J Clin Med       Date:  2022-01-28       Impact factor: 4.241

Review 8.  Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome.

Authors:  Tomer Illouz; Arya Biragyn; Maria Florencia Iulita; Lisi Flores-Aguilar; Mara Dierssen; Ilario De Toma; Stylianos E Antonarakis; Eugene Yu; Yann Herault; Marie-Claude Potier; Alexandra Botté; Randall Roper; Benjamin Sredni; Jacqueline London; William Mobley; Andre Strydom; Eitan Okun
Journal:  Front Immunol       Date:  2021-06-25       Impact factor: 7.561

  8 in total

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