Literature DB >> 2298287

A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism.

N Lucarini1, G Finocchi, F Gloria-Bottini, M Macioce, P Borgiani, A Amante, E Bottini.   

Abstract

Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.

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Year:  1990        PMID： 2298287     DOI： 10.1007/bf01955426

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  RED CELL ACID PHOSPHATASE VARIANTS: A NEW HUMAN POLYMORPHISM.

Authors:  D A HOPKINSON; N SPENCER; H HARRIS
Journal:  Nature       Date:  1963-09-07       Impact factor: 49.962

2.  Activity of the "red cell" acid phosphatase locus in other tissues.

Authors:  D M Swallow; S Povey; H Harris
Journal:  Ann Hum Genet       Date:  1973-07       Impact factor: 1.670

3.  Some notes on the geographical distribution of the human red cell acid phosphatase phenotypes.

Authors:  R Ananthakrishnan; H Walter
Journal:  Humangenetik       Date:  1972

4.  Is obesity a genetic disease?

Authors:  G B Forbes
Journal:  J Med Soc N J       Date:  1982-01

5.  ACP1GUA-1--a low-activity variant of human erythrocyte acid phosphatase: association with increased glutathione reductase activity.

Authors:  H W Mohrenweiser; J E Novotny
Journal:  Am J Hum Genet       Date:  1982-05       Impact factor: 11.025

6.  Phenotypic variation in the phosphotransferase activity of human red cell acid phosphatase (ACP1).

Authors:  V L Golden; G F Sensabaugh
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132

7.  An adoption study of human obesity.

Authors:  A J Stunkard; T I Sørensen; C Hanis; T W Teasdale; R Chakraborty; W J Schull; F Schulsinger
Journal:  N Engl J Med       Date:  1986-01-23       Impact factor: 91.245

8.  Foetal macrosomia and erythrocyte acid phosphatase (ACP1) polymorphism in diabetic and normal pregnancy.

Authors:  F Gloria-Bottini; G Gerlini; N Lucarini; P Borgiani; M C Gori; A Amante; P Lucarelli; E Bottini
Journal:  Early Hum Dev       Date:  1988 Aug-Sep       Impact factor: 2.079

9.  Predisposition to obesity.

Authors:  J S Garrow; S E Blaza; P M Warwick; M A Ashwell
Journal:  Lancet       Date:  1980-05-24       Impact factor: 79.321
  9 in total
  3 in total

1.  Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans.

Authors:  Yu-Hsiang Shu; Jaana Hartiala; Anny H Xiang; Enrique Trigo; Jean M Lawrence; Hooman Allayee; Thomas A Buchanan; Nunzio Bottini; Richard M Watanabe
Journal:  J Clin Endocrinol Metab       Date:  2009-07-21       Impact factor: 5.958

2.  A whole-genome scan for obstructive sleep apnea and obesity.

Authors:  Lyle J Palmer; Sarah G Buxbaum; Emma Larkin; Sanjay R Patel; Robert C Elston; Peter V Tishler; Susan Redline
Journal:  Am J Hum Genet       Date:  2002-12-23       Impact factor: 11.025

3.  The low molecular weight protein tyrosine phosphatase promotes adipogenesis and subcutaneous adipocyte hypertrophy.

Authors:  Stephanie M Stanford; Meghan Collins; Michael A Diaz; Zachary J Holmes; Paul Gries; Matthew R Bliss; Alessia Lodi; Vida Zhang; Stefano Tiziani; Nunzio Bottini
Journal:  J Cell Physiol       Date:  2021-02-21       Impact factor: 6.513
  3 in total

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