| Literature DB >> 2298279 |
K Suwanborirux1, C J Chang, R W Spjut, J M Cassady.
Abstract
Guided by cytotoxicity, ansamitocin P-3, a maytansinoid, was isolated in very low yield from two members of the moss family Thuidiaceae, Claopodium crispifolium (Hook.) Ren. & Card. and Anomodon attenuatus (Hedw.) Hueb. Ansamitocin P-3 showed potent cytotoxicity against the human solid tumor cell lines A-549, HT-29. A possible basis for the occurrence of this compound in mosses is discussed.Entities:
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Year: 1990 PMID： 2298279 DOI： 10.1007/bf01955435
Source DB: PubMed Journal: Experientia ISSN： 0014-4754