Literature DB >> 22966364

MicroRNA-34b has an oncogenic role in esophageal squamous cell carcinoma.

Koshiro Harata1, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Ryo Ogawa, Takeyasu Katada, Tatsuya Tanaka, Midori Shiozaki, Yoshitaka Fujii.   

Abstract

Esophageal squamous cell carcinoma (ESCC) is a common malignancy and one of the more difficult diseases to diagnose in Japan due to its poor prognosis. MicroRNAs are small non-coding RNAs of 21-23 nucleotides that regulate gene expression. MicroRNA-34b (miR-34b) has been reported to be overexpressed in various types of cancer. However, its role in ESCC has yet to be extensively studied. The present study investigated the expression of miR-34b in 88 ESCC patients. The miR-34b expression in ESCC was significantly higher than that in the corresponding normal esophageal mucosa. It was more highly expressed in tumors with more advanced stages. However, its expression did not correlate with the p53 status. Transfection of anti-miR-34b to the ESCC cells suppressed cell growth in vitro. These results suggest an oncogenic role of miR in ESCC.

Entities:  

Year:  2010        PMID： 22966364      PMCID： PMC3436259          DOI： 10.3892/ol_00000120

Source DB:  PubMed          Journal:  Oncol Lett        ISSN： 1792-1074            Impact factor:   2.967


  21 in total

1.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors:  K J Livak; T D Schmittgen
Journal:  Methods       Date:  2001-12       Impact factor: 3.608

2.  microRNA expression profile in undifferentiated gastric cancer.

Authors:  Takeyasu Katada; Hideyuki Ishiguro; Yoshiyuki Kuwabara; Masahiro Kimura; Akira Mitui; Yoichiro Mori; Ryo Ogawa; Koshiro Harata; Yoshitaka Fujii
Journal:  Int J Oncol       Date:  2009-02       Impact factor: 5.650

3.  MicroRNA expression profiles classify human cancers.

Authors:  Jun Lu; Gad Getz; Eric A Miska; Ezequiel Alvarez-Saavedra; Justin Lamb; David Peck; Alejandro Sweet-Cordero; Benjamin L Ebert; Raymond H Mak; Adolfo A Ferrando; James R Downing; Tyler Jacks; H Robert Horvitz; Todd R Golub
Journal:  Nature       Date:  2005-06-09       Impact factor: 49.962

4.  RNASEN regulates cell proliferation and affects survival in esophageal cancer patients.

Authors:  Nobuyoshi Sugito; Hideyuki Ishiguro; Yoshiyuki Kuwabara; Masahiro Kimura; Akira Mitsui; Hiroki Kurehara; Takuya Ando; Ryota Mori; Nobuhiro Takashima; Ryo Ogawa; Yoshitaka Fujii
Journal:  Clin Cancer Res       Date:  2006-11-22       Impact factor: 12.531

Review 5.  MicroRNAs and cancer.

Authors:  Michael T McManus
Journal:  Semin Cancer Biol       Date:  2003-08       Impact factor: 15.707

6.  Reduced accumulation of specific microRNAs in colorectal neoplasia.

Authors:  Michael Z Michael; Susan M O' Connor; Nicholas G van Holst Pellekaan; Graeme P Young; Robert J James
Journal:  Mol Cancer Res       Date:  2003-10       Impact factor: 5.852

7.  Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma.

Authors:  Yong Guo; Zhaoli Chen; Liang Zhang; Fang Zhou; Susheng Shi; Xiaoli Feng; Baozhong Li; Xin Meng; Xi Ma; Mingyong Luo; Kang Shao; Ning Li; Bin Qiu; Keith Mitchelson; Jing Cheng; Jie He
Journal:  Cancer Res       Date:  2008-01-01       Impact factor: 12.701

8.  p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

Authors:  Guido T Bommer; Isabelle Gerin; Ying Feng; Andrew J Kaczorowski; Rork Kuick; Robert E Love; Yali Zhai; Thomas J Giordano; Zhaohui S Qin; Bethany B Moore; Ormond A MacDougald; Kathleen R Cho; Eric R Fearon
Journal:  Curr Biol       Date:  2007-07-26       Impact factor: 10.834

9.  Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

Authors:  Valery Tarasov; Peter Jung; Berlinda Verdoodt; Dmitri Lodygin; Alexey Epanchintsev; Antje Menssen; Gunter Meister; Heiko Hermeking
Journal:  Cell Cycle       Date:  2007-05-11       Impact factor: 4.534

10.  Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.

Authors:  Tsung-Cheng Chang; Erik A Wentzel; Oliver A Kent; Kalyani Ramachandran; Michael Mullendore; Kwang Hyuck Lee; Georg Feldmann; Munekazu Yamakuchi; Marcella Ferlito; Charles J Lowenstein; Dan E Arking; Michael A Beer; Anirban Maitra; Joshua T Mendell
Journal:  Mol Cell       Date:  2007-05-31       Impact factor: 17.970
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  10 in total

Review 1.  The role of microRNA in esophageal squamous cell carcinoma.

Authors:  Kazuto Harada; Yoshifumi Baba; Takatsugu Ishimoto; Hironobu Shigaki; Keisuke Kosumi; Naoya Yoshida; Masayuki Watanabe; Hideo Baba
Journal:  J Gastroenterol       Date:  2016-01-21       Impact factor: 7.527

Review 2.  The p53/microRNA connection in gastrointestinal cancer.

Authors:  Matjaz Rokavec; Huihui Li; Longchang Jiang; Heiko Hermeking
Journal:  Clin Exp Gastroenterol       Date:  2014-09-30

3.  miR-34b inhibits nasopharyngeal carcinoma cell proliferation by targeting ubiquitin-specific peptidase 22.

Authors:  Jianyong Xiao; Yingying Li; Wenyin Zhang; Yanni Jiang; Biaoyan Du; Yuhui Tan
Journal:  Onco Targets Ther       Date:  2016-03-16       Impact factor: 4.147

Review 4.  MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer.

Authors:  Lu Zhang; Yi Liao; Liling Tang
Journal:  J Exp Clin Cancer Res       Date:  2019-02-04

5.  Identification of crucial miRNAs and genes in esophageal squamous cell carcinoma by miRNA-mRNA integrated analysis.

Authors:  Xiaowu Zhong; Guangcheng Huang; Qiang Ma; Hebin Liao; Chang Liu; Wenjie Pu; Lei Xu; Yan Cai; Xiaolan Guo
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

6.  Transcriptomic and microRNA Expression Profiles Identify Biomarkers for Predicting Neo-Chemoradiotherapy Response in Esophageal Squamous Cell Carcinomas (ESCC).

Authors:  Jian Wang; Pengyi Yu; Judong Luo; Zhiqiang Sun; Jingping Yu; Jianlin Wang
Journal:  Front Pharmacol       Date:  2021-04-15       Impact factor: 5.810

7.  Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma.

Authors:  Qingjie Min; Yan Wang; Qingnan Wu; Xianfeng Li; Huajing Teng; Jiawen Fan; Yiren Cao; Pingsheng Fan; Qimin Zhan
Journal:  JCI Insight       Date:  2021-09-08

8.  The expression of microRNA 574-3p as a predictor of postoperative outcome in patients with esophageal squamous cell carcinoma.

Authors:  Tomoyuki Okumura; Hirohumi Kojima; Takeshi Miwa; Shinichi Sekine; Isaya Hashimoto; Shozo Hojo; Takuya Nagata; Yutaka Shimada
Journal:  World J Surg Oncol       Date:  2016-08-26       Impact factor: 2.754

Review 9.  Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma.

Authors:  Hidetaka Sugihara; Takatsugu Ishimoto; Keisuke Miyake; Daisuke Izumi; Yoshifumi Baba; Naoya Yoshida; Masayuki Watanabe; Hideo Baba
Journal:  Int J Mol Sci       Date:  2015-11-24       Impact factor: 5.923

10.  MicroRNA‑34b promotes proliferation, migration and invasion of Ewing's sarcoma cells by downregulating Notch1.

Authors:  Qunshan Lu; Mei Lu; Dong Li; Shuai Zhang
Journal:  Mol Med Rep       Date:  2018-08-09       Impact factor: 2.952
  10 in total

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