BACKGROUND: Hyperintense vessels (HVs) on fluid-attenuated inversion recovery (FLAIR) are frequently observed in acute ischemic stroke (AIS). The presence of HVs represents altered blood flow from collaterals distal to arterial occlusion or stenosis. This study aimed to evaluate the prognostic value of HVs in AIS. METHODS: Fifty-four consecutive patients with acute middle cerebral artery occlusion were enrolled in the study. The location and extent of the HVs was determined by FLAIR. Clinical data were obtained and compared between patients with different grades of HVs. Additionally, the relationship between distal HVs and leptomeningeal collaterals (LMCs) was assessed using angiography. RESULTS: HVs were observed in 41 (75.9%) of the 54 patients enrolled. The initial NIHSS score was lower (p<0.001) and the infarction volume was smaller (p<0.001) in patients with distal HVs. Adjusting of other factors, regression analysis revealed that distal HVs are an independent predictor of a favorable outcome at 90 days (p=0.006; OR 0.049; 95% CI 0.006-0.420). Furthermore, the presence of distal HVs was correlated with the presence of LMCs. CONCLUSION: Distal HVs may be a marker for LMCs and act as a predictor of a favorable clinical outcome for patients with AIS.
BACKGROUND: Hyperintense vessels (HVs) on fluid-attenuated inversion recovery (FLAIR) are frequently observed in acute ischemic stroke (AIS). The presence of HVs represents altered blood flow from collaterals distal to arterial occlusion or stenosis. This study aimed to evaluate the prognostic value of HVs in AIS. METHODS: Fifty-four consecutive patients with acute middle cerebral artery occlusion were enrolled in the study. The location and extent of the HVs was determined by FLAIR. Clinical data were obtained and compared between patients with different grades of HVs. Additionally, the relationship between distal HVs and leptomeningeal collaterals (LMCs) was assessed using angiography. RESULTS: HVs were observed in 41 (75.9%) of the 54 patients enrolled. The initial NIHSS score was lower (p<0.001) and the infarction volume was smaller (p<0.001) in patients with distal HVs. Adjusting of other factors, regression analysis revealed that distal HVs are an independent predictor of a favorable outcome at 90 days (p=0.006; OR 0.049; 95% CI 0.006-0.420). Furthermore, the presence of distal HVs was correlated with the presence of LMCs. CONCLUSION: Distal HVs may be a marker for LMCs and act as a predictor of a favorable clinical outcome for patients with AIS.
Authors: A Kufner; I Galinovic; V Ambrosi; C H Nolte; M Endres; J B Fiebach; M Ebinger Journal: AJNR Am J Neuroradiol Date: 2015-05-14 Impact factor: 3.825
Authors: M Gawlitza; U Quäschling; C Hobohm; J Otto; P Voigt; K-T Hoffmann; D Lobsien Journal: AJNR Am J Neuroradiol Date: 2014-05-08 Impact factor: 3.825
Authors: Dezhi Liu; Fabien Scalzo; Neal M Rao; Jason D Hinman; Doojin Kim; Latisha K Ali; Jeffrey L Saver; Wen Sun; Qiliang Dai; Xinfeng Liu; David S Liebeskind Journal: Stroke Date: 2016-09-22 Impact factor: 7.914
Authors: L Legrand; M Tisserand; G Turc; O Naggara; M Edjlali; C Mellerio; J-L Mas; J-F Méder; J-C Baron; C Oppenheim Journal: AJNR Am J Neuroradiol Date: 2014-09-04 Impact factor: 3.825