Literature DB >> 22964731

Progress in the diagnosis of appendicitis: a report from Washington State's Surgical Care and Outcomes Assessment Program.

Frederick Thurston Drake1, Michael G Florence, Morris G Johnson, Gregory J Jurkovich, Steve Kwon, Zeila Schmidt, Richard C Thirlby, David R Flum.   

Abstract

BACKGROUND AND OBJECTIVES: Studies suggest that computed tomography and ultrasonography can effectively diagnose and rule out appendicitis, safely reducing negative appendectomies (NAs); however, some within the surgical community remain reluctant to add imaging to clinical evaluation of patients with suspected appendicitis. The Surgical Care and Outcomes Assessment Program (SCOAP) is a physician-led quality initiative that monitors performance by benchmarking processes of care and outcomes. Since 2006, accurate diagnosis of appendicitis has been a priority for SCOAP. The objective of this study was to evaluate the association between imaging and NA in the general community.
METHODS: Data were collected prospectively for consecutive appendectomy patients (age > 15 years) at nearly 60 hospitals. SCOAP data are obtained directly from clinical records, including radiological, operative, and pathological reports. Multivariate logistic regression models were used to examine the association between imaging and NA. Tests for trends over time were also conducted.
RESULTS: Among 19,327 patients (47.9% female) who underwent appendectomy, 5.4% had NA. Among patients who were imaged, frequency of NA was 4.5%, whereas among those who were not imaged, it was 15.4% (P < 0.001). This association was consistent for men (3% vs 10%, P < 0.001) and for women of reproductive age (6.9% vs 24.7%, P < 0.001). In a multivariate model adjusted for age, sex, and white blood cell count, odds of NA for patients not imaged were 3.7 times the odds for those who received imaging (95% CI: 3.0-4.4). Among SCOAP hospitals, use of imaging increased and NA decreased significantly over time; frequency of perforation was unchanged.
CONCLUSIONS: Patients who were not imaged during workup for suspected appendicitis had more than 3 times the odds of NA as those who were imaged. Routine imaging in the evaluation of patients suspected to have appendicitis can safely reduce unnecessary operations. Programs such as SCOAP improve care through peer-led, benchmarked practice change.

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Year:  2012        PMID: 22964731      PMCID: PMC3475492          DOI: 10.1097/SLA.0b013e31826a9602

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  35 in total

1.  A prospective trial of computed tomography and ultrasonography for diagnosing appendicitis in the atypical patient.

Authors:  M D Horton; S F Counter; M G Florence; M J Hart
Journal:  Am J Surg       Date:  2000-05       Impact factor: 2.565

2.  Has misdiagnosis of appendicitis decreased over time? A population-based analysis.

Authors:  D R Flum; A Morris; T Koepsell; E P Dellinger
Journal:  JAMA       Date:  2001-10-10       Impact factor: 56.272

3.  Acute appendicitis: prospective evaluation of a diagnostic algorithm integrating ultrasound and low-dose CT to reduce the need of standard CT.

Authors:  Pierre-Alexandre Poletti; Alexandra Platon; Thomas De Perrot; Francois Sarasin; Elisabeth Andereggen; Olivier Rutschmann; Elise Dupuis-Lozeron; Thomas Perneger; Pascal Gervaz; Christoph D Becker
Journal:  Eur Radiol       Date:  2011-07-30       Impact factor: 5.315

4.  Effect of cross-sectional imaging on negative appendectomy and perforation rates in children.

Authors:  K E Applegate; C J Sivit; A E Salvator; V J Borisa; D L Dudgeon; A E Stallion; E R Grisoni
Journal:  Radiology       Date:  2001-07       Impact factor: 11.105

5.  Interpretation of computed tomography does not correlate with laboratory or pathologic findings in surgically confirmed acute appendicitis.

Authors:  M J Weyant; S R Eachempati; M A Maluccio; D E Rivadeneira; S R Grobmyer; L J Hydo; P S Barie
Journal:  Surgery       Date:  2000-08       Impact factor: 3.982

6.  The value of limited computed tomography with rectal contrast in the diagnosis of acute appendicitis.

Authors:  S Walker; W Haun; J Clark; K McMillin; F Zeren; T Gilliland
Journal:  Am J Surg       Date:  2000-12       Impact factor: 2.565

7.  The use of computed tomography for the diagnosis of acute appendicitis in children does not influence the overall rate of negative appendectomy or perforation.

Authors:  M J Weyant; S R Eachempati; M A Maluccio; N Spigland; L J Hydo; P S Barie
Journal:  Surg Infect (Larchmt)       Date:  2001       Impact factor: 2.150

8.  The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis.

Authors:  David R Flum; Thomas Koepsell
Journal:  Arch Surg       Date:  2002-07

9.  Imaging for suspected appendicitis: negative appendectomy and perforation rates.

Authors:  Sandra E Bendeck; Matilde Nino-Murcia; Gerald J Berry; R Brooke Jeffrey
Journal:  Radiology       Date:  2002-10       Impact factor: 11.105

10.  Appendicitis: should diagnostic imaging be performed if the clinical presentation is highly suggestive of the disease?

Authors:  Thomas Rettenbacher; Alois Hollerweger; Norbert Gritzmann; Thaddaeus Gotwald; Klaus Schwamberger; Hanno Ulmer; Dieter Zur Nedden
Journal:  Gastroenterology       Date:  2002-10       Impact factor: 22.682

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  37 in total

1.  Safety in surgery: the role for registries.

Authors:  Michael J Lee
Journal:  Clin Orthop Relat Res       Date:  2013-06-06       Impact factor: 4.176

2.  A novel reporting system to improve accuracy in appendicitis imaging.

Authors:  Benjamin D Godwin; Frederick T Drake; Vlad V Simianu; Jabi E Shriki; Daniel S Hippe; Manjiri Dighe; Sarah Bastawrous; Carlos Cuevas; David Flum; Puneet Bhargava
Journal:  AJR Am J Roentgenol       Date:  2015-06       Impact factor: 3.959

3.  Is there a need to standardize reporting terminology in appendicitis?

Authors:  Benjamin David Godwin; Vlad Valentin Simianu; Frederick Thurston Drake; Manjiri Dighe; David Flum; Puneet Bhargava
Journal:  Ultrasound Q       Date:  2015-06       Impact factor: 1.657

4.  Appendicitis-the balance between cost effectiveness and safety remains challenging.

Authors:  Juliane Liese; Thomas M Halbinger; Frank Ulrich; Wolf O Bechstein; Christoph W Strey
Journal:  Langenbecks Arch Surg       Date:  2014-03-16       Impact factor: 3.445

Review 5.  Pediatric appendicitis: state of the art review.

Authors:  Rebecca M Rentea; Shawn D St Peter; Charles L Snyder
Journal:  Pediatr Surg Int       Date:  2016-10-14       Impact factor: 1.827

6.  Reply to letter: "Progress in the diagnosis of appendicitis".

Authors:  Frederick Thurston Drake; David R Flum
Journal:  Ann Surg       Date:  2015-03       Impact factor: 12.969

7.  Cost-effectiveness of routine imaging of suspected appendicitis.

Authors:  N D'Souza; M Marsden; S Bottomley; N Nagarajah; F Scutt; S Toh
Journal:  Ann R Coll Surg Engl       Date:  2017-10-19       Impact factor: 1.891

8.  Can We Perform CT of the Appendix with Less Than 1 mSv? A De-escalating Dose-simulation Study.

Authors:  Ji Hoon Park; Jong-June Jeon; Sung Soo Lee; Amar C Dhanantwari; Ji Ye Sim; Hae Young Kim; Kyoung Ho Lee
Journal:  Eur Radiol       Date:  2017-12-07       Impact factor: 5.315

9.  Short- and long-term mortality after appendectomy in Sweden 1987-2006: influence of appendectomy diagnosis, sex, age, co-morbidity, surgical method, hospital volume, and time period--a national population based cohort study.

Authors:  Frederick Thurston Drake; David R Flum
Journal:  World J Surg       Date:  2013-05       Impact factor: 3.352

Review 10.  Improvement in the diagnosis of appendicitis.

Authors:  Frederick Thurston Drake; David Reed Flum
Journal:  Adv Surg       Date:  2013
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