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Literature DB >> 22963870

miRNA regulates noncoding RNA: a noncanonical function model.

Xi Chen¹, Hongwei Liang, Chen-Yu Zhang, Ke Zen.

Abstract

It has long been assumed that miRNAs can only target protein-coding mRNAs in the cytoplasm. Recent studies, however, reveal miRNAs are also transported from the cytoplasm to the nucleus, where they function in a noncanonical manner to regulate noncoding RNAs. Here, we highlight the working model of these noncanonical miRNAs.

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Year: 2012 PMID： 22963870 DOI： 10.1016/j.tibs.2012.08.005

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

21 in total

Review 1. microRNAs are ligands of Toll-like receptors.

Authors: Xi Chen; Hongwei Liang; Junfeng Zhang; Ke Zen; Chen-Yu Zhang
Journal: RNA Date: 2013-04-03 Impact factor: 4.942

Review 2. Regulation of the mRNA half-life in breast cancer.

Authors: Paola Griseri; Gilles Pagès
Journal: World J Clin Oncol Date: 2014-08-10

Review 3. Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells.

Authors: Yuhai Zhao; Surjyadipta Bhattacharjee; Brandon M Jones; Jim Hill; Prerna Dua; Walter J Lukiw
Journal: Mol Neurobiol Date: 2013-11-29 Impact factor: 5.590

4. Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.

Authors: Jian Zheng; Xudong Huang; Wen Tan; Dianke Yu; Zhongli Du; Jiang Chang; Lixuan Wei; Yaling Han; Chengfeng Wang; Xu Che; Yifeng Zhou; Xiaoping Miao; Guoliang Jiang; Xianjun Yu; Xianghong Yang; Guangwen Cao; Chaohui Zuo; Zhaoshen Li; Chunyou Wang; Siu Tim Cheung; Yongfeng Jia; Xiongwei Zheng; Hongbing Shen; Chen Wu; Dongxin Lin
Journal: Nat Genet Date: 2016-05-23 Impact factor: 38.330

miRNA regulates noncoding RNA: a noncanonical function model.

Review 1. microRNAs are ligands of Toll-like receptors.

Review 2. Regulation of the mRNA half-life in breast cancer.

Review 3. Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells.

4. Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.

Review 5. ADAR enzyme and miRNA story: a nucleotide that can make the difference.

Review 6. Overview of research on Bombyx mori microRNA.

Review 7. MicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological Diseases.

8. MicroRNAs and Molecular Mechanisms of Neurodegeneration.

9. Next-generation sequencing: from understanding biology to personalized medicine.

10. Spatiotemporal Expression and Molecular Characterization of miR-344b and miR-344c in the Developing Mouse Brain.