| Literature DB >> 22963079 |
Fuhang Song1, Xinru Liu, Hui Guo, Biao Ren, Caixia Chen, Andrew M Piggott, Ke Yu, Hong Gao, Qian Wang, Mei Liu, Xueting Liu, Huanqin Dai, Lixin Zhang, Robert J Capon.
Abstract
An Aspergillus versicolor isolated from sediment collected from the Bohai Sea, China, yielded the new dimeric diketopiperazine brevianamide S (1), together with three new monomeric cometabolites, brevianamides T (2), U (3), and V (4). Structures were determined by detailed spectroscopic analysis. Brevianamide S exhibited selective antibacterial activity against Bacille Calmette-Guérin (BCG), suggestive of a new mechanism of action that could inform the development of next-generation antitubercular drugs.Entities:
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Year: 2012 PMID: 22963079 DOI: 10.1021/ol302051x
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005