BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are performed in patients with obesity and type 2 diabetes mellitus (T2DM). The aim of this study is to evaluate retrospectively the clinical efficacy of RYGB and SG in two groups of obese T2DM patients. METHODS: From the hospital database, we extracted the clinical records of 31 obese T2DM patients, of whom 15 (7 F/8 M) had undergone laparoscopic SG (LSG) and 16 (7 F/9 M) laparoscopic RYGB (LRYGB) in the period 2005-2008. The groups were comparable for age (range 33-59 years) and BMI (range 38-57 kg/m(2)). LRYGB alimentary limb was 150 cm, and biliopancreatic limb was 150 cm from the Treitz ligament. LSG vertical transection was calibrated on a 40-Fr orogastric bougie. Data were analysed at 6, 12 and 18-24 months with reference to weight loss and remission of comorbidities. RESULTS: The reduction in body weight was comparable in the two groups. At 18-24 months the percent BMI reduction was 29 ± 8 and 33 ± 11 % in LSG and LRYGB, respectively. Percent excess weight loss was 53 ± 16 and 52 ± 19 % in LSG and LRYGB, respectively. Thirteen patients in LSG and 14 patients in LRYGB discontinued their hypoglycaemic medications. Five (55 %) patients in LSG and eight (89 %) in LRYGB discontinued antihypertensive drugs. Three out of five patients in LSG and one out of two patients in LRYGB withdrew lipid-lowering agents. CONCLUSIONS: LSG and LRYGB are equally effective in terms of weight loss and remission of obesity-related comorbidities. Controlled long-term comparisons are needed to establish the optimal procedure in relation to patients' characteristics.
BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are performed in patients with obesity and type 2 diabetes mellitus (T2DM). The aim of this study is to evaluate retrospectively the clinical efficacy of RYGB and SG in two groups of obese T2DM patients. METHODS: From the hospital database, we extracted the clinical records of 31 obese T2DM patients, of whom 15 (7 F/8 M) had undergone laparoscopic SG (LSG) and 16 (7 F/9 M) laparoscopic RYGB (LRYGB) in the period 2005-2008. The groups were comparable for age (range 33-59 years) and BMI (range 38-57 kg/m(2)). LRYGB alimentary limb was 150 cm, and biliopancreatic limb was 150 cm from the Treitz ligament. LSG vertical transection was calibrated on a 40-Fr orogastric bougie. Data were analysed at 6, 12 and 18-24 months with reference to weight loss and remission of comorbidities. RESULTS: The reduction in body weight was comparable in the two groups. At 18-24 months the percent BMI reduction was 29 ± 8 and 33 ± 11 % in LSG and LRYGB, respectively. Percent excess weight loss was 53 ± 16 and 52 ± 19 % in LSG and LRYGB, respectively. Thirteen patients in LSG and 14 patients in LRYGB discontinued their hypoglycaemic medications. Five (55 %) patients in LSG and eight (89 %) in LRYGB discontinued antihypertensive drugs. Three out of five patients in LSG and one out of two patients in LRYGB withdrew lipid-lowering agents. CONCLUSIONS: LSG and LRYGB are equally effective in terms of weight loss and remission of obesity-related comorbidities. Controlled long-term comparisons are needed to establish the optimal procedure in relation to patients' characteristics.
Authors: Samuel Klein; Nancy F Sheard; Xavier Pi-Sunyer; Anne Daly; Judith Wylie-Rosett; Karmeen Kulkarni; Nathaniel G Clark Journal: Diabetes Care Date: 2004-08 Impact factor: 19.112
Authors: A M Wren; L J Seal; M A Cohen; A E Brynes; G S Frost; K G Murphy; W S Dhillo; M A Ghatei; S R Bloom Journal: J Clin Endocrinol Metab Date: 2001-12 Impact factor: 5.958
Authors: R Padwal; S Klarenbach; N Wiebe; D Birch; S Karmali; B Manns; M Hazel; A M Sharma; M Tonelli Journal: Obes Rev Date: 2011-03-28 Impact factor: 9.213
Authors: Arthur Bohdjalian; Felix B Langer; Soheila Shakeri-Leidenmühler; Lisa Gfrerer; Bernhard Ludvik; Johannes Zacherl; Gerhard Prager Journal: Obes Surg Date: 2010-01-22 Impact factor: 4.129
Authors: Tomasz Rogula; David Leifer; Jacob A Petrosky; Xiuli Liu; Michal Janik; Valerie Zeer; Piotr Fiedorczuk; Jan Baczek; Philip Schauer Journal: Obes Surg Date: 2019-02 Impact factor: 4.129
Authors: Kemal Dogan; Ralph P M Gadiot; Edo O Aarts; Bark Betzel; Cees J H M van Laarhoven; Laser U Biter; Guido H H Mannaerts; Theo J Aufenacker; Ignace M C Janssen; Frits J Berends Journal: Obes Surg Date: 2015-07 Impact factor: 4.129
Authors: Hans Eickhoff; Teresa M Louro; Paulo N Matafome; Filipa Vasconcelos; Raquel M Seiça; Francisco Castro E Sousa Journal: Obes Surg Date: 2015-01 Impact factor: 4.129