Literature DB >> 22958924

Distinct and dynamic requirements for mTOR signaling in hematopoiesis and leukemogenesis.

Alex Kentsis, A Thomas Look.   

Abstract

Signaling involving PI3K and AKT regulates cell growth, partly through the mTOR kinase complexes 1 and 2. In this issue of Cell Stem Cell, Kalaitzidis et al. and Magee et al. reveal unique requirements for mTORC1 and mTORC2 signaling during blood development and leukemogenesis induced by loss of PTEN.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22958924     DOI： 10.1016/j.stem.2012.08.007

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  9 in total

1.  Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Authors:  Fang Cao; Elizabeth C Townsend; Hacer Karatas; Jing Xu; Li Li; Shirley Lee; Liu Liu; Yong Chen; Peter Ouillette; Jidong Zhu; Jay L Hess; Peter Atadja; Ming Lei; Zhaohui S Qin; Sami Malek; Shaomeng Wang; Yali Dou
Journal:  Mol Cell       Date:  2014-01-02       Impact factor: 17.970

2.  Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture.

Authors:  Michael G Daniel; David Sachs; Jeffrey M Bernitz; Yesai Fstkchyan; Katrina Rapp; Namita Satija; Kenneth Law; Foram Patel; Andreia M Gomes; Huen-Suk Kim; Carlos-Filipe Pereira; Benjamin Chen; Ihor R Lemischka; Kateri A Moore
Journal:  FEBS Lett       Date:  2019-10-12       Impact factor: 4.124

3.  Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.

Authors:  Cuiqing Fan; Chuntao Zhao; Feng Zhang; Meenu Kesarwani; Zhaowei Tu; Xiongwei Cai; Ashley Kuenzi Davis; Lingli Xu; Cindy L Hochstetler; Xiaoyi Chen; Fukun Guo; Gang Huang; Mohammad Azam; Weidong Tian; Q Richard Lu; Yi Zheng
Journal:  Proc Natl Acad Sci U S A       Date:  2020-12-21       Impact factor: 11.205

Review 4.  The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells.

Authors:  Mary Mohrin; Danica Chen
Journal:  Curr Opin Hematol       Date:  2016-07       Impact factor: 3.284

Review 5.  mTORC signaling in hematopoiesis.

Authors:  Xiaomin Wang; Yajing Chu; Weili Wang; Weiping Yuan
Journal:  Int J Hematol       Date:  2016-01-20       Impact factor: 2.490

6.  Metabolic plasticity in stem cell homeostasis and differentiation.

Authors:  Clifford D L Folmes; Petras P Dzeja; Timothy J Nelson; Andre Terzic
Journal:  Cell Stem Cell       Date:  2012-11-02       Impact factor: 24.633

7.  Adjuvant Epigenetic Therapy of Decitabine and Suberoylanilide Hydroxamic Acid Exerts Anti-Neoplastic Effects in Acute Myeloid Leukemia Cells.

Authors:  Sonia Abou Najem; Ghada Khawaja; Mohammad Hassan Hodroj; Patil Babikian; Sandra Rizk
Journal:  Cells       Date:  2019-11-21       Impact factor: 6.600

8.  AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL.

Authors:  M J Stankiewicz; J D Crispino
Journal:  Leukemia       Date:  2013-02-05       Impact factor: 11.528

9.  Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish.

Authors:  Zhi-Wei Dong; Chun-Guang Ren; Yu Xia; Dan Su; Ting-Ting Du; Hong-Bo Fan; Hao Yuan; Lei Wang; Mei Dong; Wei-Chun Li; Yi Jin; Yi Chen; Min Deng; Ting-Xi Liu; Ai-Hua Gu; Yong Zhou
Journal:  J Hematol Oncol       Date:  2014-03-05       Impact factor: 17.388
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.