| Literature DB >> 22956026 |
Gregório Miguel Ferreira de Camargo1, Diercles Francisco Cardoso, Fernanda Maria Monsalves Gil, Patrícia Dias da Silva Fonseca, Larissa Zetouni, Camila Urbano Braz, Ana Claudia de Freitas, Fábio Ricardo Pablos de Souza, Rusbel Raul Aspilcueta-Borquis, Fernando Baldi, Lucia Galvão de Albuquerque, Luciana Correia de Almeida Regitano, Humberto Tonhati.
Abstract
Protein JY-1 is a bovine oocyte-specific protein that regulates granulosa cell function and is involved in early embryonic development, influencing the chance of pregnancy. This study investigated molecular markers for the JY-1 gene. Seven SNPs were identified in exon 3 of the gene. The positions of the SNPs in the exon and the respective substitutions are: 163 (T/C), 281 (T/C), 321 (T/C), 532 (T/C), 652 (A/G), 679 (T/C), and 722 (G/C) (GenBank: JN592587 and JF262042.2). SNP 163 is located in a coding region and causes a proline-to-leucine substitution. The other SNPs are located in the 3'UTR region. SNPs 163, 281, 321, and 679 were genotyped in 297 Nellore heifers and the haplotypes were constructed. The haplotypes of JY-1 were not correlated with the traits studied at 5 %.Entities:
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Year: 2012 PMID： 22956026 DOI： 10.1007/s11033-012-1884-5
Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316