Literature DB >> 229439

Regional distribution of a high-affinity enkephalin-degrading peptidase ('enkephalinase') and effects of lesions suggest localization in the vicinity of opiate receptors in brain.

B Malfroy, J P Swerts, C Llorens, J C Schwartz.   

Abstract

The distribution of a high affinity enkephalin-dipeptidylcarboxypeptidase between regions of mouse brain is markedly heterogenous and parallels that of opiate receptors. Furthermore intrastriatal administration of kainic acid as well as interruption of the nigrostriatal dopaminergic pathway by 6-hydroxydopamine (6-OHDA) lead to similar decreases in this peptidase activity and in the number of opiate receptors. On the contrary, no correlation was found between low affinity enkephalin degrading enzymes and opiate receptors.

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Year:  1979        PMID： 229439     DOI： 10.1016/0304-3940(79)90017-x

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  10 in total

Review 1.  Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy.

Authors:  Natalia N Nalivaeva; Anthony J Turner
Journal:  Br J Pharmacol       Date:  2019-03-11       Impact factor: 8.739

Review 2.  Pituitary endopeptidases.

Authors:  M Orlowski
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

3.  Opioid peptides as neuroregulators: potential areas for the study of genetic-behavioral mechanisms.

Authors:  J D Barchas; S Sullivan
Journal:  Behav Genet       Date:  1982-02       Impact factor: 2.805

Review 4.  Dual Enkephalinase Inhibitors and Their Role in Chronic Pain Management.

Authors:  Warren A Southerland; Justin Gillis; Sumanth Kuppalli; Alex Fonseca; Andrew Mendelson; Storm V Horine; Nitin Bansal; Amitabh Gulati
Journal:  Curr Pain Headache Rep       Date:  2021-03-24

5.  Kidney neutral endopeptidase and the hydrolysis of enkephalin by synaptic membranes show similar sensitivity to inhibitors.

Authors:  I S Fulcher; R Matsas; A J Turner; A J Kenny
Journal:  Biochem J       Date:  1982-05-01       Impact factor: 3.857

6.  The stimulation of glycogenolysis and gluconeogenesis in isolated hepatocytes by opioid peptides.

Authors:  E H Allan; I C Green; M A Titheradge
Journal:  Biochem J       Date:  1983-11-15       Impact factor: 3.857

Review 7.  Degradation of enkephalins: the search for an enkephalinase.

Authors:  L B Hersh
Journal:  Mol Cell Biochem       Date:  1982-08-20       Impact factor: 3.396

8.  Neurotransmitter uptake in various brain regions of chronically morphinized rats.

Authors:  L Rönnbäck; E Hansson; A Cupello; M V Rapallino; J Zeuchner; L Rosengren
Journal:  Neurochem Res       Date:  1986-02       Impact factor: 3.996

9.  Modulation of cholecystokinin concentrations in the rat hippocampus by chelation of heavy metals.

Authors:  K Stengaard-Pedersen; L I Larsson; K Fredens; J F Rehfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

10.  Neuronal localization of the neutral endopeptidase 'enkephalinase' in rat brain revealed by lesions and autoradiography.

Authors:  G Waksman; E Hamel; P Delay-Goyet; B P Roques
Journal:  EMBO J       Date:  1986-12-01       Impact factor: 11.598
  10 in total

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