Literature DB >> 22937855

Incidental vestibular schwannomas: a review of prevalence, growth rate, and management challenges.

Richard F Schmidt1, Zain Boghani, Osamah J Choudhry, Jean Anderson Eloy, Robert W Jyung, James K Liu.   

Abstract

With the relatively recent increase in the use of MRI techniques, there has been a concurrent rise in the number of vestibular schwannomas (VSs) detected as incidental findings. These incidental VSs may be prevalent in up to 0.02%-0.07% of individuals undergoing MRI and represent a significant portion of all diagnosed VSs. The management of these lesions poses a significant challenge for practitioners. Most incidental VSs tend to be small and associated with minimal symptoms, permitting them to be managed conservatively at the time of diagnosis. However, relatively few indicators consistently predict tumor growth and patient outcomes. Furthermore, growth rates have been shown to vary significantly over time with a large variety of long-term growth patterns. Thus, early MRI screening for continued tumor growth followed by repeated MRI studies and clinical assessments throughout the patient's life is an essential component in a conservative management strategy. Note that tumor growth is typically associated with a worsening of symptoms in patients who undergo conservative management, and many of these symptoms have been shown to significantly impact the patient's quality of life. Specific indications for the termination of conservative management vary across studies, but secondary intervention has been shown to be a relatively safe option in most patients with progressive disease. Patients with incidental VSs will probably qualify for a course of conservative management at diagnosis, and regular imaging combined with the expectation that the tumor and symptoms may change at any interval is crucial to ensuring positive long-term outcomes in these patients. In this report, the authors discuss the current literature pertaining to the prevalence of incidental VSs and various considerations in the management of these lesions. It is hoped that by incorporating an understanding of tumor growth, patient outcomes, and management strategies, practitioners will be able to effectively address this challenging disease entity.

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Year:  2012        PMID: 22937855     DOI: 10.3171/2012.7.FOCUS12186

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  11 in total

1.  The impact of MRI steady-state sequences as an additional assessment modality in vestibular schwannoma patients after LINAC stereotactic radiotherapy or radiosurgery.

Authors:  Julian P Sauer; Thomas M Kinfe; Bogdan Pintea; Andreas Schäfer; Jan P Boström
Journal:  Strahlenther Onkol       Date:  2018-05-23       Impact factor: 3.621

2.  Medical Malpractice of Vestibular Schwannoma: A 40-Year Review of the United States Legal Databases.

Authors:  Jack Birkenbeuel; Kimberly Vu; Brandon M Lehrich; Mehdi Abouzari; Dillon Cheung; Pooya Khosravi; Ronald Sahyouni; Kasra Ziai; Omid Moshtaghi; Sammy Sahyouni; Hamid R Djalilian
Journal:  Otol Neurotol       Date:  2019-03       Impact factor: 2.311

3.  Cost-effectiveness analysis of a non-contrast screening MRI protocol for vestibular schwannoma in patients with asymmetric sensorineural hearing loss.

Authors:  Matthew G Crowson; Daniel J Rocke; Jenny K Hoang; Jane L Weissman; David M Kaylie
Journal:  Neuroradiology       Date:  2017-06-16       Impact factor: 2.804

Review 4.  Assessing the long-term safety and efficacy of gamma knife and linear accelerator radiosurgery for vestibular schwannoma: A systematic review and meta-analysis.

Authors:  Sergio W Guadix; Alice J Tao; Anjile An; Michelle Demetres; Umberto Tosi; Swathi Chidambaram; Jonathan P S Knisely; Rohan Ramakrishna; Susan C Pannullo
Journal:  Neurooncol Pract       Date:  2021-08-13

5.  Prevalence of Sporadic Vestibular Schwannoma: Reconciling Temporal Bone, Radiologic, and Population-based Studies.

Authors:  John P Marinelli; Brandon R Grossardt; Christine M Lohse; Matthew L Carlson
Journal:  Otol Neurotol       Date:  2019-03       Impact factor: 2.311

6.  Incidence of Vestibular Schwannoma over the Past Half-Century: A Population-Based Study of Olmsted County, Minnesota.

Authors:  John P Marinelli; Christine M Lohse; Matthew L Carlson
Journal:  Otolaryngol Head Neck Surg       Date:  2018-05-01       Impact factor: 3.497

7.  A Suspected Vestibular Schwannoma with Uncharacteristic Growth Dynamic and Symptom Severity: A Case Report.

Authors:  Felix Ehret; Alexander Muacevic
Journal:  Cureus       Date:  2018-01-05

8.  Current Understanding of Hearing Loss in Sporadic Vestibular Schwannomas: A Systematic Review.

Authors:  Jinlu Gan; Yanling Zhang; Jingnan Wu; Deqiang Lei; Fangcheng Zhang; Hongyang Zhao; Lei Wang
Journal:  Front Oncol       Date:  2021-08-12       Impact factor: 6.244

9.  Signs and Symptoms of Acoustic Neuroma at Initial Presentation: An Exploratory Analysis.

Authors:  Robert W Foley; Shahram Shirazi; Robert M Maweni; Kay Walsh; Rory McConn Walsh; Mohsen Javadpour; Daniel Rawluk
Journal:  Cureus       Date:  2017-11-15

Review 10.  Biomarkers in Vestibular Schwannoma-Associated Hearing Loss.

Authors:  Luis Lassaletta; Miryam Calvino; Jose Manuel Morales-Puebla; Pablo Lapunzina; Lourdes Rodriguez-de la Rosa; Isabel Varela-Nieto; Victor Martinez-Glez
Journal:  Front Neurol       Date:  2019-09-18       Impact factor: 4.003

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