Literature DB >> 22932499

Incomplete methylation reprogramming in SCNT embryos.

Julian R Peat1, Wolf Reik.   

Abstract

The cloning of Dolly the sheep was a remarkable demonstration of the oocyte's ability to reprogram a specialized nucleus. However, embryos derived from such somatic cell nuclear transfer (SCNT) very rarely result in live births-a fate that may be linked to observed epigenetic defects. A new genome-wide study shows that epigenetic reprogramming in SCNT embryos does not fully recapitulate the natural DNA demethylation events occurring at fertilization, resulting in aberrant methylation at some promoters and repetitive elements that may contribute to developmental failure.

Entities:  

Mesh：

Year:  2012        PMID： 22932499     DOI： 10.1038/ng.2393

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

Review 1.  Transposable elements in the mammalian germline: a comfortable niche or a deadly trap?

Authors:  N Zamudio; D Bourc'his
Journal:  Heredity (Edinb)       Date:  2010-05-05       Impact factor: 3.821

2.  Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.

Authors:  Mark Wossidlo; Julia Arand; Vittorio Sebastiano; Konstantin Lepikhov; Michele Boiani; Richard Reinhardt; Hans Schöler; Jörn Walter
Journal:  EMBO J       Date:  2010-05-04       Impact factor: 11.598

3.  5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.

Authors:  Mark Wossidlo; Toshinobu Nakamura; Konstantin Lepikhov; C Joana Marques; Valeri Zakhartchenko; Michele Boiani; Julia Arand; Toru Nakano; Wolf Reik; Jörn Walter
Journal:  Nat Commun       Date:  2011       Impact factor: 14.919

4.  The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.

Authors:  Tian-Peng Gu; Fan Guo; Hui Yang; Hai-Ping Wu; Gui-Fang Xu; Wei Liu; Zhi-Guo Xie; Linyu Shi; Xinyi He; Seung-gi Jin; Khursheed Iqbal; Yujiang Geno Shi; Zixin Deng; Piroska E Szabó; Gerd P Pfeifer; Jinsong Li; Guo-Liang Xu
Journal:  Nature       Date:  2011-09-04       Impact factor: 49.962

5.  Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway.

Authors:  Petra Hajkova; Sean J Jeffries; Caroline Lee; Nigel Miller; Stephen P Jackson; M Azim Surani
Journal:  Science       Date:  2010-07-02       Impact factor: 47.728

6.  Dynamic CpG island methylation landscape in oocytes and preimplantation embryos.

Authors:  Sébastien A Smallwood; Shin-Ichi Tomizawa; Felix Krueger; Nico Ruf; Natasha Carli; Anne Segonds-Pichon; Shun Sato; Kenichiro Hata; Simon R Andrews; Gavin Kelsey
Journal:  Nat Genet       Date:  2011-06-26       Impact factor: 38.330

7.  A unique regulatory phase of DNA methylation in the early mammalian embryo.

Authors:  Zachary D Smith; Michelle M Chan; Tarjei S Mikkelsen; Hongcang Gu; Andreas Gnirke; Aviv Regev; Alexander Meissner
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

8.  Mouse ooplasm confers context-specific reprogramming capacity.

Authors:  Michelle M Chan; Zachary D Smith; Dieter Egli; Aviv Regev; Alexander Meissner
Journal:  Nat Genet       Date:  2012-08-19       Impact factor: 38.330

9.  Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

Authors:  Cassandra R Farthing; Gabriella Ficz; Ray Kit Ng; Chun-Fung Chan; Simon Andrews; Wendy Dean; Myriam Hemberger; Wolf Reik
Journal:  PLoS Genet       Date:  2008-06-27       Impact factor: 5.917

10.  A role for the elongator complex in zygotic paternal genome demethylation.

Authors:  Yuki Okada; Kazuo Yamagata; Kwonho Hong; Teruhiko Wakayama; Yi Zhang
Journal:  Nature       Date:  2010-01-06       Impact factor: 49.962
View more
  24 in total

1.  Epigenetic Modification of Cloned Embryos Improves Nanog Reprogramming in Pigs.

Authors:  Yanjun Huan; Hongmei Wang; Zhanfeng Wu; Jiguang Zhang; Jiang Zhu; Zhonghua Liu; Hongbin He
Journal:  Cell Reprogram       Date:  2015-06       Impact factor: 1.987

2.  Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer: Data Analysis with Over 200,000 Reconstructed Embryos.

Authors:  Tianbin Liu; Hongwei Dou; Xi Xiang; Lin Li; Yong Li; Lin Lin; Xinzhi Pang; Yijie Zhang; Yu Chen; Jing Luan; Ying Xu; Zhenzhen Yang; Wenxian Yang; Huan Liu; Feida Li; Hui Wang; Huanming Yang; Lars Bolund; Gabor Vajta; Yutao Du
Journal:  Cell Reprogram       Date:  2015-12       Impact factor: 1.987

3.  Imprinted genes and satellite loci are differentially methylated in bovine somatic cell nuclear transfer clones.

Authors:  Chih-Jie Shen; Chiao-Chieh Lin; Perng-Chih Shen; Winston T K Cheng; Hsiao-Ling Chen; Tsung-Chou Chang; Shyh-Shyan Liu; Chuan-Mu Chen
Journal:  Cell Reprogram       Date:  2013-08-20       Impact factor: 1.987

4.  Reshaping the transcriptional frontier: epigenetics and somatic cell nuclear transfer.

Authors:  Charles R Long; Mark E Westhusin; Michael C Golding
Journal:  Mol Reprod Dev       Date:  2013-12-13       Impact factor: 2.609

Review 5.  Nutritional Status Impacts Epigenetic Regulation in Early Embryo Development: A Scoping Review.

Authors:  Shuang Cai; Shuang Quan; Guangxin Yang; Meixia Chen; Qianhong Ye; Gang Wang; Haitao Yu; Yuming Wang; Shiyan Qiao; Xiangfang Zeng
Journal:  Adv Nutr       Date:  2021-10-01       Impact factor: 8.701

6.  Effects of DNMT1 and HDAC inhibitors on gene-specific methylation reprogramming during porcine somatic cell nuclear transfer.

Authors:  Weihua Xu; Zicong Li; Bo Yu; Xiaoyan He; Junsong Shi; Rong Zhou; Dewu Liu; Zhenfang Wu
Journal:  PLoS One       Date:  2013-05-31       Impact factor: 3.240

7.  Epigenetic Modification Agents Improve Gene-Specific Methylation Reprogramming in Porcine Cloned Embryos.

Authors:  Yanjun Huan; Zhanfeng Wu; Jiguang Zhang; Jiang Zhu; Zhonghua Liu; Xuexiong Song
Journal:  PLoS One       Date:  2015-06-11       Impact factor: 3.240

8.  Trichostatin A rescues the disrupted imprinting induced by somatic cell nuclear transfer in pigs.

Authors:  Yanjun Huan; Jiang Zhu; Bo Huang; Yanshuang Mu; Qingran Kong; Zhonghua Liu
Journal:  PLoS One       Date:  2015-05-11       Impact factor: 3.240

9.  Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency.

Authors:  Tetsuya Ito; Yutaka Sendai; Satoshi Yamazaki; Marie Seki-Soma; Kensuke Hirose; Motoo Watanabe; Kazuo Fukawa; Hiromitsu Nakauchi
Journal:  PLoS One       Date:  2014-12-01       Impact factor: 3.240

10.  The transcriptomic architecture of mouse Sertoli cell clone embryos reveals temporal–spatial-specific reprogramming.

Authors:  Feng Cao; Atsushi Fukuda; Hiroshi Watanabe; Tomohiro Kono
Journal:  Reproduction       Date:  2013-03-01       Impact factor: 3.906
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.