Literature DB >> 22921416

The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease.

Péter Bai1, Carles Cantó.   

Abstract

While originally described as DNA damage repair agents, recent data suggest a role for poly(ADP-ribose) polymerase (PARP) enzymes in metabolic regulation by influencing mitochondrial function and oxidative metabolism. Here we review how PARP activity has a major metabolic impact and the role of PARP-1 and PARP-2 in diverse metabolic complications.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22921416     DOI： 10.1016/j.cmet.2012.06.016

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  106 in total

1.  Metabolic responses induced by DNA damage and poly (ADP-ribose) polymerase (PARP) inhibition in MCF-7 cells.

Authors:  Vijesh J Bhute; Sean P Palecek
Journal:  Metabolomics       Date:  2015-07-30       Impact factor: 4.290

2.  Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.

Authors:  Hisayuki Amano; Arindam Chaudhury; Cristian Rodriguez-Aguayo; Lan Lu; Viktor Akhanov; Andre Catic; Yury V Popov; Eric Verdin; Hannah Johnson; Fabio Stossi; David A Sinclair; Eiko Nakamaru-Ogiso; Gabriel Lopez-Berestein; Jeffrey T Chang; Joel R Neilson; Alan Meeker; Milton Finegold; Joseph A Baur; Ergun Sahin
Journal:  Cell Metab       Date:  2019-03-28       Impact factor: 27.287

3.  Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography.

Authors:  Jun Yoshino; Shin-Ichiro Imai
Journal:  Methods Mol Biol       Date:  2013

4.  Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy.

Authors:  Katharina Danhauser; Bader Alhaddad; Christine Makowski; Dorota Piekutowska-Abramczuk; Steffen Syrbe; Natalia Gomez-Ospina; Melanie A Manning; Anna Kostera-Pruszczyk; Claudia Krahn-Peper; Riccardo Berutti; Reka Kovács-Nagy; Mirjana Gusic; Elisabeth Graf; Lucia Laugwitz; Michaela Röblitz; Andreas Wroblewski; Hans Hartmann; Anibh M Das; Eva Bültmann; Fang Fang; Manting Xu; Ulrich A Schatz; Daniela Karall; Herta Zellner; Edda Haberlandt; René G Feichtinger; Johannes A Mayr; Thomas Meitinger; Holger Prokisch; Tim M Strom; Rafał Płoski; Georg F Hoffmann; Maciej Pronicki; Penelope E Bonnen; Susanne Morlot; Tobias B Haack
Journal:  Am J Hum Genet       Date:  2018-10-25       Impact factor: 11.025

5.  Stress response: PARP1 911.

Authors:  Florian J Bock; Paul Chang
Journal:  Nat Chem Biol       Date:  2015-03       Impact factor: 15.040

Review 6.  NAD+ metabolism and its roles in cellular processes during ageing.

Authors:  Anthony J Covarrubias; Rosalba Perrone; Alessia Grozio; Eric Verdin
Journal:  Nat Rev Mol Cell Biol       Date:  2020-12-22       Impact factor: 94.444

Review 7.  Non-coding RNAs: the dark side of nuclear-mitochondrial communication.

Authors:  Roberto Vendramin; Jean-Christophe Marine; Eleonora Leucci
Journal:  EMBO J       Date:  2017-03-17       Impact factor: 11.598

8.  Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality.

Authors:  Shaimaa Ahmed; Debbie Bott; Alvin Gomez; Laura Tamblyn; Adil Rasheed; Tiffany Cho; Laura MacPherson; Kim S Sugamori; Yang Yang; Denis M Grant; Carolyn L Cummins; Jason Matthews
Journal:  J Biol Chem       Date:  2015-05-13       Impact factor: 5.157

9.  Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage.

Authors:  Xuanye Cao; Chaoqun Li; Siyu Xiao; Yunlan Tang; Jing Huang; Shuan Zhao; Xueyu Li; Jixi Li; Ruilin Zhang; Wei Yu
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-09       Impact factor: 11.205

Review 10.  Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy.

Authors:  Zoltán V Varga; Zoltán Giricz; Lucas Liaudet; György Haskó; Peter Ferdinandy; Pál Pacher
Journal:  Biochim Biophys Acta       Date:  2014-07-02
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