Literature DB >> 24014409

Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography.

Jun Yoshino1, Shin-Ichiro Imai.   

Abstract

Nicotinamide adenine dinucleotide (NAD(+)) plays a critical role in regulating numerous biological and physiological pathways including metabolism, inflammation, cancer, and aging in mammals. Here we describe a highly quantitative method with reverse-phase high-performance liquid chromatography (HPLC) for the determination of NAD(+) levels in cells and tissues. This methodology provides accurate, reliable, and reproducible results of NAD(+) measurement, which enables us to analyze various pathophysiological changes in NAD(+) levels in vitro and in vivo.

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Year:  2013        PMID： 24014409      PMCID： PMC3935825          DOI： 10.1007/978-1-62703-637-5_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  31 in total

1.  The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.

Authors:  Maria Thereza P Barbosa; Sandra M Soares; Colleen M Novak; David Sinclair; James A Levine; Pinar Aksoy; Eduardo Nunes Chini
Journal:  FASEB J       Date:  2007-06-21       Impact factor: 5.191

Review 2.  Enzymology of NAD+ synthesis.

Authors:  G Magni; A Amici; M Emanuelli; N Raffaelli; S Ruggieri
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1999

Review 3.  Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers.

Authors:  H C Lee
Journal:  Annu Rev Pharmacol Toxicol       Date:  2001       Impact factor: 13.820

Review 4.  The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals.

Authors:  Javier R Revollo; Andrew A Grimm; Shin-ichiro Imai
Journal:  Curr Opin Gastroenterol       Date:  2007-03       Impact factor: 3.287

Review 5.  NAD+ metabolism in health and disease.

Authors:  Peter Belenky; Katrina L Bogan; Charles Brenner
Journal:  Trends Biochem Sci       Date:  2006-12-11       Impact factor: 13.807

6.  Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme.

Authors:  Javier R Revollo; Antje Körner; Kathryn F Mills; Akiko Satoh; Tao Wang; Antje Garten; Biplab Dasgupta; Yo Sasaki; Cynthia Wolberger; R Reid Townsend; Jeffrey Milbrandt; Wieland Kiess; Shin-Ichiro Imai
Journal:  Cell Metab       Date:  2007-11       Impact factor: 27.287

7.  The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.

Authors:  Javier R Revollo; Andrew A Grimm; Shin-ichiro Imai
Journal:  J Biol Chem       Date:  2004-09-20       Impact factor: 5.157

Review 8.  Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.

Authors:  Katrina L Bogan; Charles Brenner
Journal:  Annu Rev Nutr       Date:  2008       Impact factor: 11.848

9.  FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.

Authors:  Max Hasmann; Isabel Schemainda
Journal:  Cancer Res       Date:  2003-11-01       Impact factor: 12.701

Review 10.  Functional aspects of protein mono-ADP-ribosylation.

Authors:  Daniela Corda; Maria Di Girolamo
Journal:  EMBO J       Date:  2003-05-01       Impact factor: 11.598
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  32 in total

1.  SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.

Authors:  Josiah Gerdts; E J Brace; Yo Sasaki; Aaron DiAntonio; Jeffrey Milbrandt
Journal:  Science       Date:  2015-04-23       Impact factor: 47.728

Review 2.  Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses.

Authors:  Joshua E Lewis; Naveen Singh; Reetta J Holmila; Baran D Sumer; Noelle S Williams; Cristina M Furdui; Melissa L Kemp; David A Boothman
Journal:  Semin Radiat Oncol       Date:  2019-01       Impact factor: 5.934

3.  NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice.

Authors:  Kelly L Stromsdorfer; Shintaro Yamaguchi; Myeong Jin Yoon; Anna C Moseley; Michael P Franczyk; Shannon C Kelly; Nathan Qi; Shin-Ichiro Imai; Jun Yoshino
Journal:  Cell Rep       Date:  2016-08-04       Impact factor: 9.423

4.  CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

Authors:  Juliana Camacho-Pereira; Mariana G Tarragó; Claudia C S Chini; Veronica Nin; Carlos Escande; Gina M Warner; Amrutesh S Puranik; Renee A Schoon; Joel M Reid; Antonio Galina; Eduardo N Chini
Journal:  Cell Metab       Date:  2016-06-14       Impact factor: 27.287

Review 5.  Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy.

Authors:  Shintaro Yamaguchi; Jun Yoshino
Journal:  Bioessays       Date:  2017-03-15       Impact factor: 4.345

Review 6.  Circadian regulation of cellular physiology.

Authors:  C B Peek; K M Ramsey; D C Levine; B Marcheva; M Perelis; J Bass
Journal:  Methods Enzymol       Date:  2015-01-05       Impact factor: 1.600

7.  Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection.

Authors:  Alexander L Kolb; Peter R Corridon; Shijun Zhang; Weimin Xu; Frank A Witzmann; Jason A Collett; George J Rhodes; Seth Winfree; Devin Bready; Zechariah J Pfeffenberger; Jeremy M Pomerantz; Takashi Hato; Glenn T Nagami; Bruce A Molitoris; David P Basile; Simon J Atkinson; Robert L Bacallao
Journal:  J Am Soc Nephrol       Date:  2018-01-25       Impact factor: 10.121

8.  Detection of cerebral NAD+ in humans at 7T.

Authors:  Robin A de Graaf; Henk M De Feyter; Peter B Brown; Terence W Nixon; Douglas L Rothman; Kevin L Behar
Journal:  Magn Reson Med       Date:  2016-09-26       Impact factor: 4.668

Review 9.  NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential.

Authors:  Na Xie; Lu Zhang; Wei Gao; Canhua Huang; Peter Ernst Huber; Xiaobo Zhou; Changlong Li; Guobo Shen; Bingwen Zou
Journal:  Signal Transduct Target Ther       Date:  2020-10-07

10.  NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.

Authors:  Jonathan B Lin; Shunsuke Kubota; Norimitsu Ban; Mitsukuni Yoshida; Andrea Santeford; Abdoulaye Sene; Rei Nakamura; Nicole Zapata; Miyuki Kubota; Kazuo Tsubota; Jun Yoshino; Shin-Ichiro Imai; Rajendra S Apte
Journal:  Cell Rep       Date:  2016-09-27       Impact factor: 9.423
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