Literature DB >> 22920181

Epigenetics and childhood asthma: current evidence and future research directions.

Muhammad T Salam1, Ying Zhang, Kohinoor Begum.   

Abstract

Asthma is the most common chronic disease of childhood, affecting one in eight children in the USA and worldwide. It is a complex disease, influenced by both environmental exposures and genetic factors. Although epigenetic modifications (DNA methylation, histone modification and miRNA) can affect transcriptional activity in multiple genetic pathways relevant for asthma development, very limited work has been carried out so far to examine the role of epigenetic variations on asthma development and management. This review provides a brief overview of epigenetic modifications, summarizes recent findings, and discusses some of the major methodological concerns that are relevant for asthma epigenetics.

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Year:  2012        PMID： 22920181      PMCID： PMC3458510          DOI： 10.2217/epi.12.32

Source DB:  PubMed          Journal:  Epigenomics        ISSN： 1750-192X            Impact factor:   4.778


  120 in total

1.  PTGDR gene in asthma: a functional, genetic, and epigenetic study.

Authors:  M Isidoro-García; C Sanz; V García-Solaesa; M Pascual; D B Pescador; F Lorente; I Dávila
Journal:  Allergy       Date:  2011-08-24       Impact factor: 13.146

2.  Association between single-nucleotide polymorphisms in pre-miRNAs and the risk of asthma in a Chinese population.

Authors:  Xiao-Wei Su; Yan Yang; Mei-Li Lv; Li-Juan Li; Wei Dong; Lin-Bo Gao; Hai-Bo Luo; Rui-Juan Cong; Wei-Bo Liang; Ying-Bi Li
Journal:  DNA Cell Biol       Date:  2011-06-11       Impact factor: 3.311

3.  Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children.

Authors:  Muhammad T Salam; Hyang-Min Byun; Fred Lurmann; Carrie V Breton; Xinhui Wang; Sandrah P Eckel; Frank D Gilliland
Journal:  J Allergy Clin Immunol       Date:  2011-11-04       Impact factor: 10.793

4.  Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes.

Authors:  Stephanie Brand; René Teich; Tanja Dicke; Hani Harb; Ali Ö Yildirim; Jörg Tost; Regine Schneider-Stock; Robert A Waterland; Uta-Maria Bauer; Erika von Mutius; Holger Garn; Petra I Pfefferle; Harald Renz
Journal:  J Allergy Clin Immunol       Date:  2011-06-15       Impact factor: 10.793

Review 5.  T regulatory cells in childhood asthma.

Authors:  Deborah H Strickland; Patrick G Holt
Journal:  Trends Immunol       Date:  2011-07-27       Impact factor: 16.687

6.  Prenatal smoke exposure and genomic DNA methylation in a multiethnic birth cohort.

Authors:  Julie D Flom; Jennifer S Ferris; Yuyan Liao; Parisa Tehranifar; Clara Belessiotis Richards; Yoon Hee Cho; Karina Gonzalez; Regina M Santella; Mary Beth Terry
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-10-12       Impact factor: 4.254

7.  Birthweight, maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements.

Authors:  Karin B Michels; Holly R Harris; Ludovic Barault
Journal:  PLoS One       Date:  2011-09-28       Impact factor: 3.240

8.  In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta.

Authors:  Charlotte S Wilhelm-Benartzi; E Andres Houseman; Matthew A Maccani; Graham M Poage; Devin C Koestler; Scott M Langevin; Luc A Gagne; Carolyn E Banister; James F Padbury; Carmen J Marsit
Journal:  Environ Health Perspect       Date:  2011-10-17       Impact factor: 9.031

9.  MiR-221 influences effector functions and actin cytoskeleton in mast cells.

Authors:  Ramon J Mayoral; Lorenzo Deho; Nicole Rusca; Nenad Bartonicek; Harpreet Kaur Saini; Anton J Enright; Silvia Monticelli
Journal:  PLoS One       Date:  2011-10-12       Impact factor: 3.240

10.  Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes.

Authors:  Isaac K Sundar; Sangwoon Chung; Jae-Woong Hwang; John D Lapek; Michael Bulger; Alan E Friedman; Hongwei Yao; James R Davie; Irfan Rahman
Journal:  PLoS One       Date:  2012-02-01       Impact factor: 3.240
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  12 in total

Review 1.  Epigenetics of inflammation, maternal infection, and nutrition.

Authors:  Kate J Claycombe; Catherine A Brissette; Othman Ghribi
Journal:  J Nutr       Date:  2015-04-01       Impact factor: 4.798

2.  Air Pollution and the Epigenome: A Model Relationship for the Exploration of Toxicoepigenetics.

Authors:  Shaun D McCullough; Radhika Dhingra; Marie C Fortin; David Diaz-Sanchez
Journal:  Curr Opin Toxicol       Date:  2017-10-01

Review 3.  DNA methylation-based variation between human populations.

Authors:  Farzeen Kader; Meenu Ghai
Journal:  Mol Genet Genomics       Date:  2016-11-04       Impact factor: 3.291

Review 4.  Beyond the genome: epigenetic mechanisms in lung remodeling.

Authors:  James S Hagood
Journal:  Physiology (Bethesda)       Date:  2014-05

5.  Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status.

Authors:  Katherine King; Susan Murphy; Cathrine Hoyo
Journal:  J Epidemiol Community Health       Date:  2015-02-12       Impact factor: 3.710

Review 6.  Epigenetics in immune-mediated pulmonary diseases.

Authors:  Yu Liu; Hui Li; Tao Xiao; Qianjin Lu
Journal:  Clin Rev Allergy Immunol       Date:  2013-12       Impact factor: 8.667

7.  Health and Well-Being Outcomes of Adolescents Conceived Through In Vitro Fertilization and Intracytoplasmic Sperm Injection.

Authors:  Marie-José Gervoise-Boyer; Any Beltran Anzola; Roland Sambuc; Maria Katsogiannou; Pierre Boyer
Journal:  Reprod Sci       Date:  2020-11-25       Impact factor: 3.060

Review 8.  Epigenetics of discordant monozygotic twins: implications for disease.

Authors:  Juan E Castillo-Fernandez; Tim D Spector; Jordana T Bell
Journal:  Genome Med       Date:  2014-07-31       Impact factor: 11.117

9.  Identification of Epigenetic Mechanisms Involved in the Anti-Asthmatic Effects of Descurainia sophia Seed Extract Based on a Multi-Omics Approach.

Authors:  Su-Jin Baek; Jin Mi Chun; Tae-Wook Kang; Yun-Soo Seo; Sung-Bae Kim; Boseok Seong; Yunji Jang; Ga-Hee Shin; Chul Kim
Journal:  Molecules       Date:  2018-11-05       Impact factor: 4.411

10.  Exposure to traffic-related air pollution and changes in exhaled nitric oxide and DNA methylation in arginase and nitric oxide synthase in children with asthma.

Authors:  N Ji; M Fang; A Baptista; C Cepeda; M Greenberg; I Colon Mincey; P Ohman-Strickland; F Haynes; N Fiedler; H M Kipen; R J Laumbach
Journal:  Environ Health       Date:  2021-02-11       Impact factor: 5.984
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