Literature DB >> 22918619

CSF diversion in refractory idiopathic intracranial hypertension: single-centre experience and review of efficacy.

Georgios Niotakis1, Dionysios Grigoratos, Chris Chandler, Danny Morrison, Ming Lim.   

Abstract

PURPOSE: The current surgical management strategies for refractory cases of idiopathic intracranial hypertension (IIH) remain unresolved. We evaluated the outcome of our paediatric patients who were offered a CSF diversion procedure in order to control their symptoms.
METHODS: We retrospectively reviewed the medical notes of the patients under 16 years of age, who presented in our centre from 2005 to 2010, with a confirmed diagnosis of IIH, and ultimately had a lumboperitoneal shunt (LPS). We describe their immediate postoperative course, shunt-related complications and recent outcome.
RESULTS: Seven patients presented at a mean age of 8.7 years. Two presented with significant visual loss and had a shunt acutely; the remaining five presented with headaches and were shunted within 2 years. In the immediate postoperative period two patients experienced low-pressure symptoms. All patients required shunt revisions; in total 15 revisions took place, mainly secondary to symptomatic overdrainage or obstruction. After a mean follow-up of 26 months, two patients have diminished visual acuity at least on one side; only one patient became headache-free, despite resolution of the CSF pressure post diversion in four out of the six remaining patients.
CONCLUSIONS: All patients required shunt revisions and 6/7 (85.7%) had persisting headaches at their last follow-up. It is apparent that once functional, the LPS seems adequate to lower the CSF pressure but not effective in eliminating symptoms.

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Year:  2012        PMID: 22918619     DOI: 10.1007/s00381-012-1895-5

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  14 in total

Review 1.  Diagnostic criteria for idiopathic intracranial hypertension.

Authors:  Deborah I Friedman; Daniel M Jacobson
Journal:  Neurology       Date:  2002-11-26       Impact factor: 9.910

2.  Fulminant idiopathic intracranial hypertension.

Authors:  Madhav Thambisetty; Patrick J Lavin; Nancy J Newman; Valérie Biousse
Journal:  Neurology       Date:  2007-01-16       Impact factor: 9.910

Review 3.  Idiopathic intracranial hypertension in children: a review and algorithm.

Authors:  Shannon M Standridge
Journal:  Pediatr Neurol       Date:  2010-12       Impact factor: 3.372

4.  Transverse sinus stenting for idiopathic intracranial hypertension: a review of 52 patients and of model predictions.

Authors:  R M Ahmed; M Wilkinson; G D Parker; M J Thurtell; J Macdonald; P J McCluskey; R Allan; V Dunne; M Hanlon; B K Owler; G M Halmagyi
Journal:  AJNR Am J Neuroradiol       Date:  2011-07-28       Impact factor: 3.825

5.  Reference range for cerebrospinal fluid opening pressure in children.

Authors:  Robert A Avery; Samir S Shah; Daniel J Licht; Jeffrey A Seiden; Jimmy W Huh; Jan Boswinkel; Michael D Ruppe; Amber Chew; Rakesh D Mistry; Grant T Liu
Journal:  N Engl J Med       Date:  2010-08-26       Impact factor: 91.245

Review 6.  Interventions for idiopathic intracranial hypertension.

Authors:  C Lueck; G McIlwaine
Journal:  Cochrane Database Syst Rev       Date:  2005-07-20

7.  Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intractable headache: predictors of treatment response and an analysis of long-term outcomes.

Authors:  Matthew J McGirt; Graeme Woodworth; George Thomas; Neil Miller; Michael Williams; Daniele Rigamonti
Journal:  J Neurosurg       Date:  2004-10       Impact factor: 5.115

Review 8.  Pediatric idiopathic intracranial hypertension.

Authors:  Lubaina M Rangwala; Grant T Liu
Journal:  Surv Ophthalmol       Date:  2007 Nov-Dec       Impact factor: 6.048

9.  Concurrent use of a lumboperitoneal shunt with programmable valve and ventricular access device in the treatment of pseudotumor cerebri: review of 40 cases.

Authors:  Trimurti D Nadkarni; Harold L Rekate; Donna Wallace
Journal:  J Neurosurg Pediatr       Date:  2008-07       Impact factor: 2.375

Review 10.  Idiopathic intracranial hypertension: 12 cases treated by venous sinus stenting.

Authors:  J N P Higgins; C Cousins; B K Owler; N Sarkies; J D Pickard
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-12       Impact factor: 10.154

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  5 in total

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Journal:  Neuroophthalmology       Date:  2016-09-23

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Review 3.  [Treatment of idiopathic intracranial hypertension by endovascular improvement of venous drainage of the brain].

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Journal:  Ophthalmologe       Date:  2015-10       Impact factor: 1.059

4.  Over-drainage and persistent shunt-dependency in patients with idiopathic intracranial hypertension treated with shunts and bariatric surgery.

Authors:  Jonathan Roth; Shlomi Constantini; Anat Kesler
Journal:  Surg Neurol Int       Date:  2015-12-08

5.  Persistent shunt dependency and very late shunt failure in a 3-year-old boy with idiopathic intracranial hypertension (IIH).

Authors:  Anne Henriette Paulsen; Bernt Johan Due-Tønnessen; Tryggve Lundar; Karl-Fredrik Lindegaard
Journal:  Childs Nerv Syst       Date:  2016-12-17       Impact factor: 1.475

  5 in total

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