OBJECTIVE: The purpose of this study was to compare the differences in kinetic assessments of lesions at breast MRI performed with higher and lower temporal resolution. MATERIALS AND METHODS: All consecutively evaluated BI-RADS category 4, 5, and 6 lesions imaged with breast MRI and pathologically confirmed from October 2005 to August 2009 were identified. Patients underwent MRI with one of two dynamic contrast-enhanced protocols: one with 90-second (October 2005-June 2006) and another with 180-second (July 2006-August 2009) temporal resolution. Studies were processed with a computer-aided evaluation system with initial and delayed contrast-enhanced time points with the k-space centered 90 and 450 seconds after contrast injection. Initial-phase peak enhancement, delayed-phase predominant curve type, and worst curve type were recorded and compared for benign and malignant lesions across protocols. RESULTS: The analysis set comprised 993 lesions: 145 imaged with the 90-second acquisition (17 benign, 28 ductal carcinoma in situ [DCIS], 100 invasive cancer) and 848 imaged with the 180-second acquisition (212 benign, 145 DCIS, 491 invasive cancer). Peak enhancement was significantly higher for both benign lesions (p = 0.01) and invasive cancers (p = 0.0008) with the 180-second protocol. Peak enhancement of DCIS was similar in the two protocols (p = 0.88). Delayed-phase kinetics were similar for the two protocols for both benign and malignant lesions when defined by predominant or worst curve type. CONCLUSION: Although it has lower temporal resolution, a 180-second acquisition may be preferable because it allows higher spatial resolution and captures higher initial-phase peak enhancement without loss of delayed-phase kinetic information.
OBJECTIVE: The purpose of this study was to compare the differences in kinetic assessments of lesions at breast MRI performed with higher and lower temporal resolution. MATERIALS AND METHODS: All consecutively evaluated BI-RADS category 4, 5, and 6 lesions imaged with breast MRI and pathologically confirmed from October 2005 to August 2009 were identified. Patients underwent MRI with one of two dynamic contrast-enhanced protocols: one with 90-second (October 2005-June 2006) and another with 180-second (July 2006-August 2009) temporal resolution. Studies were processed with a computer-aided evaluation system with initial and delayed contrast-enhanced time points with the k-space centered 90 and 450 seconds after contrast injection. Initial-phase peak enhancement, delayed-phase predominant curve type, and worst curve type were recorded and compared for benign and malignant lesions across protocols. RESULTS: The analysis set comprised 993 lesions: 145 imaged with the 90-second acquisition (17 benign, 28 ductal carcinoma in situ [DCIS], 100 invasive cancer) and 848 imaged with the 180-second acquisition (212 benign, 145 DCIS, 491 invasive cancer). Peak enhancement was significantly higher for both benign lesions (p = 0.01) and invasive cancers (p = 0.0008) with the 180-second protocol. Peak enhancement of DCIS was similar in the two protocols (p = 0.88). Delayed-phase kinetics were similar for the two protocols for both benign and malignant lesions when defined by predominant or worst curve type. CONCLUSION: Although it has lower temporal resolution, a 180-second acquisition may be preferable because it allows higher spatial resolution and captures higher initial-phase peak enhancement without loss of delayed-phase kinetic information.
Authors: Elizabeth S McDonald; Jennifer G Schopp; Sue Peacock; Wendy B DeMartini; Wendy D DeMartini; Habib Rahbar; Constance D Lehman; Savannah C Partridge Journal: AJR Am J Roentgenol Date: 2014-05 Impact factor: 3.959
Authors: Anna G Sorace; Savannah C Partridge; Xia Li; Jack Virostko; Stephanie L Barnes; Daniel S Hippe; Wei Huang; Thomas E Yankeelov Journal: J Med Imaging (Bellingham) Date: 2018-01-22
Authors: Savannah C Partridge; Karen M Stone; Roberta M Strigel; Wendy B DeMartini; Sue Peacock; Constance D Lehman Journal: Acad Radiol Date: 2014-07-04 Impact factor: 3.173
Authors: Curtis A Corum; John C Benson; Djaudat Idiyatullin; Angela L Snyder; Carl J Snyder; Diane Hutter; Lenore I Everson; Lynn E Eberly; Michael T Nelson; Michael Garwood Journal: Radiology Date: 2014-09-22 Impact factor: 11.105