Literature DB >> 22910439

The relevance of "missing heritability " in pharmacogenomics.

W Sadee1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22910439      PMCID： PMC3638892          DOI： 10.1038/clpt.2012.116

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


× No keyword cloud information.
  5 in total

1.  The mystery of missing heritability: Genetic interactions create phantom heritability.

Authors:  Or Zuk; Eliana Hechter; Shamil R Sunyaev; Eric S Lander
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-05       Impact factor: 11.205

Review 2.  Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy.

Authors:  W Sadee; D Wang; A C Papp; J K Pinsonneault; R M Smith; R A Moyer; A D Johnson
Journal:  Clin Pharmacol Ther       Date:  2011-02-02       Impact factor: 6.875

3.  Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs.

Authors:  D Wang; Y Guo; S A Wrighton; G E Cooke; W Sadee
Journal:  Pharmacogenomics J       Date:  2010-04-13       Impact factor: 3.550

Review 4.  The DNA damage response and cancer therapy.

Authors:  Christopher J Lord; Alan Ashworth
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

5.  Catecholamine receptor polymorphisms affect decision-making in C. elegans.

Authors:  Andres Bendesky; Makoto Tsunozaki; Matthew V Rockman; Leonid Kruglyak; Cornelia I Bargmann
Journal:  Nature       Date:  2011-03-16       Impact factor: 49.962
  5 in total
  8 in total

Review 1.  Pharmacokinetics and Pharmacogenetics of Carbamazepine in Children.

Authors:  Natasa Djordjevic; Slobodan M Jankovic; Jasmina R Milovanovic
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2017-10       Impact factor: 2.441

Review 2.  Genomic architecture of pharmacological efficacy and adverse events.

Authors:  Aparna Chhibber; Deanna L Kroetz; Kelan G Tantisira; Michael McGeachie; Cheng Cheng; Robert Plenge; Eli Stahl; Wolfgang Sadee; Marylyn D Ritchie; Sarah A Pendergrass
Journal:  Pharmacogenomics       Date:  2014-12       Impact factor: 2.533

3.  Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.

Authors:  Danxin Wang; Katherine Hartmann; Michal Seweryn; Wolfgang Sadee
Journal:  Circ Genom Precis Med       Date:  2018-10

4.  Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.

Authors:  Danxin Wang; Ming J Poi; Xiaochun Sun; Andrea Gaedigk; J Steven Leeder; Wolfgang Sadee
Journal:  Hum Mol Genet       Date:  2013-08-28       Impact factor: 6.150

Review 5.  Missing heritability of common diseases and treatments outside the protein-coding exome.

Authors:  Wolfgang Sadee; Katherine Hartmann; Michał Seweryn; Maciej Pietrzak; Samuel K Handelman; Grzegorz A Rempala
Journal:  Hum Genet       Date:  2014-08-09       Impact factor: 4.132

Review 6.  Uncovering drug-responsive regulatory elements.

Authors:  Marcelo R Luizon; Nadav Ahituv
Journal:  Pharmacogenomics       Date:  2015-11-10       Impact factor: 2.533

7.  Genome-wide discovery of drug-dependent human liver regulatory elements.

Authors:  Robin P Smith; Walter L Eckalbar; Kari M Morrissey; Marcelo R Luizon; Thomas J Hoffmann; Xuefeng Sun; Stacy L Jones; Shelley Force Aldred; Anuradha Ramamoorthy; Zeruesenay Desta; Yunlong Liu; Todd C Skaar; Nathan D Trinklein; Kathleen M Giacomini; Nadav Ahituv
Journal:  PLoS Genet       Date:  2014-10-02       Impact factor: 5.917

8.  Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Authors:  Kathrin Klein; Ulrich M Zanger
Journal:  Front Genet       Date:  2013-02-25       Impact factor: 4.599
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.