Literature DB >> 22910438

Strategies for personalized medicine-based research and implementation in the clinical workflow.

W Lieb1, H Völzke, J M Pulley, D M Roden, H K Kroemer.   

Abstract

The decoding of the human genome, paralleled by the development of high-throughput technologies to obtain large-scale molecular data (e.g., information on genetic variations, transcription levels, and metabolite concentrations) is providing new insights into the molecular basis of common diseases and the causes of variability in drug response. This article presents strategies to incorporate this new knowledge into research and clinical workflow.

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Mesh：

Year:  2012        PMID： 22910438     DOI： 10.1038/clpt.2012.119

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  7 in total

Review 1.  Pharmacogenomics of hypertension and heart disease.

Authors:  Meghan J Arwood; Larisa H Cavallari; Julio D Duarte
Journal:  Curr Hypertens Rep       Date:  2015-09       Impact factor: 5.369

2.  A pharmacogenetics service experience for pharmacy students, residents, and fellows.

Authors:  Katarzyna Drozda; Yana Labinov; Ruixuan Jiang; Margaret R Thomas; Shan S Wong; Shitalben Patel; Edith A Nutescu; Larisa H Cavallari
Journal:  Am J Pharm Educ       Date:  2013-10-14       Impact factor: 2.047

Review 3.  Pharmacogenomics in cardiology--genetics and drug response: 10 years of progress.

Authors:  Larisa H Cavallari; Kristin Weitzel
Journal:  Future Cardiol       Date:  2015-05

4.  The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation.

Authors:  A R Shuldiner; M V Relling; J F Peterson; J K Hicks; R R Freimuth; W Sadee; N L Pereira; D M Roden; J A Johnson; T E Klein; Alan R Shuldiner; Mark Vesely; Shawn W Robinson; Nicholas Ambulos; Sanford A Stass; Mark D Kelemen; Lawrence A Brown; Toni I Pollin; Amber L Beitelshees; Richard Y Zhao; Ruth E Pakyz; Kathleen Palmer; Tameka Alestock; Courtney O'Neill; Kristin Maloney; Amie Branham; Danielle Sewell; Mary V Relling; Kristine Crews; James Hoffman; Shane Cross; Cyrine Haidar; Don Baker; J Kevin Hicks; Gillian Bell; Fran Greeson; Aditya Gaur; Ulrike Reiss; Alicia Huettel; Cheng Cheng; Amar Gajjar; Alberto Pappo; Scott Howard; Melissa Hudson; Ching-Hon Pui; Sima Jeha; William E Evans; Ulrich Broeckel; Russ B Altman; Li Gong; Michelle Whirl-Carrillo; Teri E Klein; Wolfgang Sadee; Kandamurugu Manickam; Kevin M Sweet; Peter J Embi; Dan Roden; Josh Peterson; Josh Denny; Jonathan Schildcrout; Erica Bowton; Jill Pulley; Marc Beller; Jennifer Mitchell; Ioana Danciu; Lisa Price; Naveen L Pereira; Richard Weinshilboum; Liewei Wang; Julie A Johnson; David Nelson; Michael Clare-Salzler; Amanda Elsey; Benjamin Burkley; Taimour Langaee; Felix Liu; David Nessl; Hui-Jia Dong; Larry Lesko; Robert R Freimuth; Christopher G Chute
Journal:  Clin Pharmacol Ther       Date:  2013-03-19       Impact factor: 6.875

Review 5.  Clopidogrel and warfarin pharmacogenetic tests: what is the evidence for use in clinical practice?

Authors:  Mohamed H A Shahin; Julie A Johnson
Journal:  Curr Opin Cardiol       Date:  2013-05       Impact factor: 2.161

Review 6.  Pharmacogenetics and cardiovascular disease--implications for personalized medicine.

Authors:  Julie A Johnson; Larisa H Cavallari
Journal:  Pharmacol Rev       Date:  2013-05-17       Impact factor: 25.468

7.  Feasibility of implementing a comprehensive warfarin pharmacogenetics service.

Authors:  Edith A Nutescu; Katarzyna Drozda; Adam P Bress; William L Galanter; James Stevenson; Thomas D Stamos; Ankit A Desai; Julio D Duarte; Victor Gordeuk; David Peace; Shrihari S Kadkol; Carol Dodge; Santosh Saraf; John Garofalo; Jerry A Krishnan; Joe G N Garcia; Larisa H Cavallari
Journal:  Pharmacotherapy       Date:  2013-07-17       Impact factor: 4.705
  7 in total

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