| Literature DB >> 22901307 |
Sara H Rouhanifard1, Ran Xie, Guoxin Zhang, Xiaoming Sun, Xing Chen, Peng Wu.
Abstract
dendritic cell (DC)-specific intracellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN) is a receptor found on DCs that recognizes antigens bearing mannose-rich or fucosylated glycans, including Lewis X (Le(X)). Here, we report the fabrication of magnetic nanoparticles coated with multivalent Le(X) glycans using Cu (I)-catalyzed azide-alkyne cycloaddition. The resulting nanoparticles are selective and biocompatible, serving as a highly efficient tool for DC detection and enrichment.Entities:
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Year: 2012 PMID: 22901307 PMCID: PMC3470862 DOI: 10.1021/bm3007506
Source DB: PubMed Journal: Biomacromolecules ISSN: 1525-7797 Impact factor: 6.988