Literature DB >> 22901266

Enhancing engraftment of cord blood cells via insight into the biology of stem/progenitor cell function.

Hal E Broxmeyer1.   

Abstract

Cord blood (CB) transplantation has been used over the last 24 years to treat patients with malignant and nonmalignant disorders. CB has its advantages and disadvantages compared with other sources of hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) for transplantation. More knowledge of the cytokines and intracellular signaling molecules regulating HSCs and HPCs could be used to modulate these regulators for clinical benefit. This review provides information about the general field of CB transplantation and about studies from the author's laboratory that focus on regulation of HSCs and HPCs by CD26/DPPIV, SDF-1/CXCL12, the Rheb2-mTOR pathway, SIRT1, DEK, cyclin-dependent kinase inhibitors, and cytokines/growth factors. Cryopreservation of CB HSCs and HPCs is also briefly discussed.
© 2012 New York Academy of Sciences.

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Year:  2012        PMID： 22901266      PMCID： PMC3428743          DOI： 10.1111/j.1749-6632.2012.06509.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  93 in total

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Authors:  Tanja Waldmann; Ingo Scholten; Ferdinand Kappes; Hong Gang Hu; Rolf Knippers
Journal:  Gene       Date:  2004-12-08       Impact factor: 3.688

2.  Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients.

Authors:  J Kurtzberg; M Laughlin; M L Graham; C Smith; J F Olson; E C Halperin; G Ciocci; C Carrier; C E Stevens; P Rubinstein
Journal:  N Engl J Med       Date:  1996-07-18       Impact factor: 91.245

3.  High-efficiency recovery of immature haematopoietic progenitor cells with extensive proliferative capacity from human cord blood cryopreserved for 10 years.

Authors:  H E Broxmeyer; S Cooper
Journal:  Clin Exp Immunol       Date:  1997-01       Impact factor: 4.330

4.  Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.

Authors:  A Peled; I Petit; O Kollet; M Magid; T Ponomaryov; T Byk; A Nagler; H Ben-Hur; A Many; L Shultz; O Lider; R Alon; D Zipori; T Lapidot
Journal:  Science       Date:  1999-02-05       Impact factor: 47.728

5.  Outcome of cord-blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Transplantation Group.

Authors:  E Gluckman; V Rocha; A Boyer-Chammard; F Locatelli; W Arcese; R Pasquini; J Ortega; G Souillet; E Ferreira; J P Laporte; M Fernandez; C Chastang
Journal:  N Engl J Med       Date:  1997-08-07       Impact factor: 91.245

6.  Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease.

Authors:  J E Wagner; J Rosenthal; R Sweetman; X O Shu; S M Davies; N K Ramsay; P B McGlave; L Sender; M S Cairo
Journal:  Blood       Date:  1996-08-01       Impact factor: 22.113

7.  Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia.

Authors:  Mary J Laughlin; Mary Eapen; Pablo Rubinstein; John E Wagner; Mei-Jei Zhang; Richard E Champlin; Cladd Stevens; Juliet N Barker; Robert P Gale; Hillard M Lazarus; David I Marks; Jon J van Rood; Andromachi Scaradavou; Mary M Horowitz
Journal:  N Engl J Med       Date:  2004-11-25       Impact factor: 91.245

8.  Involvement of p21cip-1 and p27kip-1 in the molecular mechanisms of steel factor-induced proliferative synergy in vitro and of p21cip-1 in the maintenance of stem/progenitor cells in vivo.

Authors:  C Mantel; Z Luo; J Canfield; S Braun; C Deng; H E Broxmeyer
Journal:  Blood       Date:  1996-11-15       Impact factor: 22.113

9.  Outcomes among 562 recipients of placental-blood transplants from unrelated donors.

Authors:  P Rubinstein; C Carrier; A Scaradavou; J Kurtzberg; J Adamson; A R Migliaccio; R L Berkowitz; M Cabbad; N L Dobrila; P E Taylor; R E Rosenfield; C E Stevens
Journal:  N Engl J Med       Date:  1998-11-26       Impact factor: 91.245

10.  Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow.

Authors:  Lijun Xia; J Michael McDaniel; Tadayuki Yago; Andrea Doeden; Rodger P McEver
Journal:  Blood       Date:  2004-07-27       Impact factor: 22.113
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  11 in total

Review 1.  Cord Blood Banking for Potential Future Transplantation.

Authors:  William T Shearer; Bertram H Lubin; Mitchell S Cairo; Luigi D Notarangelo
Journal:  Pediatrics       Date:  2017-11       Impact factor: 7.124

2.  Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model.

Authors:  Maegan L Capitano; Giao Hangoc; Scott Cooper; Hal E Broxmeyer
Journal:  Stem Cells       Date:  2015-06       Impact factor: 6.277

3.  Pharmacological inhibition of AKT activity in human CD34+ cells enhances their ability to engraft immunodeficient mice.

Authors:  Sisi Chen; Rui Gao; Michihiro Kobayashi; Hao Yu; Chonghua Yao; Reuben Kapur; Mervin C Yoder; Yan Liu
Journal:  Exp Hematol       Date:  2016-09-17       Impact factor: 3.084

4.  Total body irradiation is permissive for mesenchymal stem cell-mediated new bone formation following local transplantation.

Authors:  Samuel Herberg; Galina Kondrikova; Khaled A Hussein; Sudharsan Periyasamy-Thandavan; Maribeth H Johnson; Mohammed E Elsalanty; Xingming Shi; Mark W Hamrick; Carlos M Isales; William D Hill
Journal:  Tissue Eng Part A       Date:  2014-12       Impact factor: 3.845

5.  Factors That Influence a Mother's Willingness to Preserve Umbilical Cord Blood: A Survey of 5120 Chinese Mothers.

Authors:  Haiyan Lu; Yanwen Chen; Qiaofen Lan; Huanjin Liao; Jing Wu; Haiyan Xiao; Carol A Dickerson; Ping Wu; Qingjun Pan
Journal:  PLoS One       Date:  2015-12-09       Impact factor: 3.240

6.  Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts.

Authors:  Mateusz Adamiak; Ahmed Abdel-Latif; Kamila Bujko; Arjun Thapa; Krzysztof Anusz; Michał Tracz; Katarzyna Brzezniakiewicz-Janus; Janina Ratajczak; Magda Kucia; Mariusz Z Ratajczak
Journal:  Stem Cell Rev Rep       Date:  2020-10       Impact factor: 5.739

7.  A novel application for a 3-dimensional timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133(+) stem/progenitor cells.

Authors:  Emma E Pepperell; Suzanne M Watt
Journal:  Stem Cell Res       Date:  2013-04-19       Impact factor: 2.020

8.  TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).

Authors:  Y Liu; R Raheja; N Yeh; D Ciznadija; A M Pedraza; T Ozawa; E Hukkelhoven; H Erdjument-Bromage; P Tempst; N P Gauthier; C Brennan; E C Holland; A Koff
Journal:  Oncogene       Date:  2013-01-14       Impact factor: 9.867

Review 9.  Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells.

Authors:  Mariusz Z Ratajczak; Malwina Suszynska
Journal:  Stem Cell Rev Rep       Date:  2016-02       Impact factor: 5.739

10.  Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments.

Authors:  Saloomeh Mokhtari; Pedro M Baptista; Dipen A Vyas; Charles Jordan Freeman; Emma Moran; Matthew Brovold; Guillermo A Llamazares; Zanneta Lamar; Christopher D Porada; Shay Soker; Graça Almeida-Porada
Journal:  Stem Cells Transl Med       Date:  2018-02-23       Impact factor: 6.940
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