Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.

Literature DB >> 22886872

Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.

You-Yong Yuan¹, Cheng-Qiong Mao, Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang.

Abstract

Two faced nanoparticles: A zwitterionic polymer-based nanoparticle with response to tumor acidity is developed for enhanced drug delivery to tumors. The nanoparticles are neutrally charged at physiological conditions and show prolonged circulation time; after leaking into tumor sites, in the acidic extracellular tumor environment (pH(e) ), nanoparticles are activated and become positively charged and are therefore efficiently taken up by tumor cells, leading to enhanced therapeutic effects in cancer treatment.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2012 PMID： 22886872 DOI： 10.1002/adma.201202296

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

Keyword Cloud
Cited

73 in total

Review 1. Polymeric Nanostructures for Imaging and Therapy.

Authors: Mahmoud Elsabahy; Gyu Seong Heo; Soon-Mi Lim; Guorong Sun; Karen L Wooley
Journal: Chem Rev Date: 2015-08-04 Impact factor: 60.622

2. Diagnostic and Therapeutic Nanomedicine.

Authors: Jinmyoung Joo
Journal: Adv Exp Med Biol Date: 2021 Impact factor: 2.622

Review 3. Diverse Applications of Nanomedicine.

Authors: Beatriz Pelaz; Christoph Alexiou; Ramon A Alvarez-Puebla; Frauke Alves; Anne M Andrews; Sumaira Ashraf; Lajos P Balogh; Laura Ballerini; Alessandra Bestetti; Cornelia Brendel; Susanna Bosi; Monica Carril; Warren C W Chan; Chunying Chen; Xiaodong Chen; Xiaoyuan Chen; Zhen Cheng; Daxiang Cui; Jianzhong Du; Christian Dullin; Alberto Escudero; Neus Feliu; Mingyuan Gao; Michael George; Yury Gogotsi; Arnold Grünweller; Zhongwei Gu; Naomi J Halas; Norbert Hampp; Roland K Hartmann; Mark C Hersam; Patrick Hunziker; Ji Jian; Xingyu Jiang; Philipp Jungebluth; Pranav Kadhiresan; Kazunori Kataoka; Ali Khademhosseini; Jindřich Kopeček; Nicholas A Kotov; Harald F Krug; Dong Soo Lee; Claus-Michael Lehr; Kam W Leong; Xing-Jie Liang; Mei Ling Lim; Luis M Liz-Marzán; Xiaowei Ma; Paolo Macchiarini; Huan Meng; Helmuth Möhwald; Paul Mulvaney; Andre E Nel; Shuming Nie; Peter Nordlander; Teruo Okano; Jose Oliveira; Tai Hyun Park; Reginald M Penner; Maurizio Prato; Victor Puntes; Vincent M Rotello; Amila Samarakoon; Raymond E Schaak; Youqing Shen; Sebastian Sjöqvist; Andre G Skirtach; Mahmoud G Soliman; Molly M Stevens; Hsing-Wen Sung; Ben Zhong Tang; Rainer Tietze; Buddhisha N Udugama; J Scott VanEpps; Tanja Weil; Paul S Weiss; Itamar Willner; Yuzhou Wu; Lily Yang; Zhao Yue; Qian Zhang; Qiang Zhang; Xian-En Zhang; Yuliang Zhao; Xin Zhou; Wolfgang J Parak
Journal: ACS Nano Date: 2017-03-14 Impact factor: 15.881

4. Zwitterionic Polymer Coating Suppresses Microglial Encapsulation to Neural Implants In Vitro and In Vivo.

Authors: Qianru Yang; Bingchen Wu; James R Eles; Alberto L Vazquez; Takashi D Y Kozai; X Tracy Cui
Journal: Adv Biosyst Date: 2020-05-04

5. Reversibly extracellular pH controlled cellular uptake and photothermal therapy by PEGylated mixed-charge gold nanostars.

Authors: Shouju Wang; Zhaogang Teng; Peng Huang; Dingbin Liu; Ying Liu; Ying Tian; Jing Sun; Yanjun Li; Huangxian Ju; Xiaoyuan Chen; Guangming Lu
Journal: Small Date: 2015-01-07 Impact factor: 13.281

Review 6. The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective.

Authors: Yongjiang Li; Ciceron Ayala-Orozco; Pradipta Ranjan Rauta; Sunil Krishnan
Journal: Nanoscale Date: 2019-09-18 Impact factor: 7.790

Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.

Review 1. Polymeric Nanostructures for Imaging and Therapy.

2. Diagnostic and Therapeutic Nanomedicine.

Review 3. Diverse Applications of Nanomedicine.

4. Zwitterionic Polymer Coating Suppresses Microglial Encapsulation to Neural Implants In Vitro and In Vivo.

5. Reversibly extracellular pH controlled cellular uptake and photothermal therapy by PEGylated mixed-charge gold nanostars.

Review 6. The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective.

Review 7. Biodegradable Stimuli-Responsive Polymeric Micelles for Treatment of Malignancy.

Review 8. Cellular uptake of nanoparticles: journey inside the cell.

9. Non-invasive, real-time reporting drug release in vitro and in vivo.

10. Zwitterionic Amphiphilic Homopolymer Assemblies.