Literature DB >> 22886202

Paradoxical use of oral and topical steroids in steroid-phobic patients resorting to traditional Chinese medicines.

Kam-Lun E Hon1, Ting Fan Leung, Ho Chung Yau, Thomas Chan.   

Abstract

BACKGROUND: Childhood-onset eczema is a common condition associated with pruritus, sleep disturbance and disrupted quality of life. The mainstay of treatment is usage of emollients and topical corticosteroid (CS). Nevertheless, many steroid-phobic parents are very skeptical about western medicine that may contain CS. Furthermore, complementary and alternative medicine (CAM) is popular among Chinese patients in Asia and many citizens idolize CAM and believe that traditional Chinese medicine and herbs are without any side effects. Pressed by public's quest for efficacious and safe treatment, and lucrative profits, CAM practitioners may take the risks of prescribing steroids and "western medicine" in the name of traditional Chinese herbal medicine.
METHODS: We report a series of illustrative cases of uninformed systemic and topical corticosteroid usage for eczema by steroid-phobic parents to alert the public of this risk. The drugs were detected by high-performance liquid chromatography with diode-array detection, liquid chromatography-tandem mass spectrometry, gas chromatography mass spectrometry, or liquid chromatography ion trap time-of-flight mass spectrometry.
RESULTS: Five cases of uninformed corticosteroid usage for moderate-to-severe eczema by steroid-phobic parents were reported.
CONCLUSIONS: The physician caring for children with skin disease should also be aware that even steroid-phobic parents might indeed be using potent CS without awareness. The patient usually suffers chronic relapsing eczema of moderate-to-severe degree. The steroid-phobic parent is usually non-compliant in following advice on usage of emollient, topical CS, and avoidance of triggers in accordance with western doctors. The CAM practitioner, when confronted by an anxious steroidophobic parent who demands efficacious topical and/or systemic treatment, may knowingly or unknowingly be forced into prescribing potent albeit illegal products containing corticosteroids in the name of traditional Chinese herbal medicine.

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Year:  2012        PMID: 22886202     DOI: 10.1007/s12519-012-0369-x

Source DB:  PubMed          Journal:  World J Pediatr            Impact factor:   2.764


  24 in total

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Authors:  R Graham-Brown
Journal:  Lancet       Date:  1992-09-12       Impact factor: 79.321

2.  Powerful proprietary Chinese medicine for eczema?

Authors:  K L Hon; A K Leung
Journal:  Clin Exp Dermatol       Date:  2010-04       Impact factor: 3.470

3.  Analysis of Chinese herbal creams prescribed for dermatological conditions.

Authors:  F M Keane; S E Munn; A W du Vivier; N F Taylor; E M Higgins
Journal:  BMJ       Date:  1999-02-27

4.  Prevalence of asthma and allergy in Hong Kong schoolchildren: an ISAAC study.

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Journal:  Eur Respir J       Date:  1997-02       Impact factor: 16.671

5.  Topical corticosteroid phobia in patients with atopic eczema.

Authors:  C R Charman; A D Morris; H C Williams
Journal:  Br J Dermatol       Date:  2000-05       Impact factor: 9.302

6.  Chinese herbal remedies may contain steroids.

Authors:  R A Graham-Brown; J F Bourke; G Bumphrey
Journal:  BMJ       Date:  1994-02-12

7.  Low-dose triamcinolone acetonide in the phytocosmetic lichtena reduces inflammation in mild to moderate atopic dermatitis.

Authors:  Carolina Pellanda; Monika Weber; Andreas Bircher; Christian Surber
Journal:  Dermatology       Date:  2005       Impact factor: 5.366

8.  Herbal creams used for atopic eczema in Birmingham, UK illegally contain potent corticosteroids.

Authors:  H M Ramsay; W Goddard; S Gill; C Moss
Journal:  Arch Dis Child       Date:  2003-12       Impact factor: 3.791

9.  Outcome of children with life-threatening asthma necessitating pediatric intensive care.

Authors:  Kam-Lun Hon; Wing-Sum Winnie Tang; Ting-Fan Leung; Kam-Lau Cheung; Pak-Cheung Ng
Journal:  Ital J Pediatr       Date:  2010-07-06       Impact factor: 2.638

10.  Chinese herbal medicine research in eczema treatment.

Authors:  Kam Lun Hon; Ben Chung-Lap Chan; Ping Chung Leung
Journal:  Chin Med       Date:  2011-04-28       Impact factor: 5.455

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  7 in total

1.  Stop tarnishing steroid and Chinese medicine.

Authors:  Kam Lun E Hon; Vivian Wing Yan Lee; Ting Fan Leung
Journal:  World J Pediatr       Date:  2015-11-07       Impact factor: 2.764

Review 2.  Experimental Drugs with the Potential to Treat Atopic Eczema.

Authors:  Kam Lun Ellis Hon; Vivian P Y Chan; Alexander K C Leung
Journal:  J Exp Pharmacol       Date:  2021-05-12

Review 3.  Dismissing the fallacies of childhood eczema management: case scenarios and an overview of best practices.

Authors:  Kam Lun Hon; Kin Fon Leong; Theresa Nh Leung; Alexander Kc Leung
Journal:  Drugs Context       Date:  2018-12-03

Review 4.  Steroid Phobia: Is There a Basis? A Review of Topical Steroid Safety, Addiction and Withdrawal.

Authors:  Sean Yilong Tan; Nisha Suyien Chandran; Ellie Ci-En Choi
Journal:  Clin Drug Investig       Date:  2021-08-18       Impact factor: 2.859

5.  Qualitative analysis of topical corticosteroid concerns, topical steroid addiction and withdrawal in dermatological patients.

Authors:  Sean Tan; Phillip Phan; Je Yin Law; Ellie Choi; Nisha Suyien Chandran
Journal:  BMJ Open       Date:  2022-03-16       Impact factor: 2.692

6.  Cupping Therapy May be Harmful for Eczema: A PubMed Search.

Authors:  Kam Lun E Hon; David Chi Kong Luk; Kin Fon Leong; Alexander K C Leung
Journal:  Case Rep Pediatr       Date:  2013-10-27

7.  Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study.

Authors:  Kao-Sung Tsai; Chia-Sung Yen; Po-Yuan Wu; Jen-Huai Chiang; Jui-Lung Shen; Chung-Hsien Yang; Huey-Yi Chen; Yung-Hsiang Chen; Wen-Chi Chen
Journal:  Evid Based Complement Alternat Med       Date:  2015-10-05       Impact factor: 2.629

  7 in total

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