Literature DB >> 22885756

Discovery of a novel (+)-γ-lactamase from Bradyrhizobium japonicum USDA 6 by rational genome mining.

Shaozhou Zhu1, Cuiyu Gong, Dawei Song, Shuaihua Gao, Guojun Zheng.   

Abstract

A novel (+)-γ-lactamase used for the resolution of racemic γ-lactam from Bradyrhizobium japonicum USDA 6 was found as a result of sequence-structure guided genome mining. It consists of 409 amino acids, only 49% of which are identical to the amino acid sequences of the known (+)-γ-lactamase from Sulfolobus solfataricus. This is only the third (+)-γ-lactamase gene to be reported.

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Year:  2012        PMID： 22885756      PMCID： PMC3457094          DOI： 10.1128/AEM.01398-12

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  15 in total

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3.  Crystallization and X-ray diffraction measurements of a thermophilic archaeal recombinant amidase from Sulfolobus solfataricus MT4.

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Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2001-06-21

Review 4.  Screening for novel enzymes for biocatalytic processes: accessing the metagenome as a resource of novel functional sequence space.

Authors:  Patrick Lorenz; Klaus Liebeton; Frank Niehaus; Jürgen Eck
Journal:  Curr Opin Biotechnol       Date:  2002-12       Impact factor: 9.740

Review 5.  Abacavir.

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6.  Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.

Authors:  S Staszewski; P Keiser; J Montaner; F Raffi; J Gathe; V Brotas; C Hicks; S M Hammer; D Cooper; M Johnson; S Tortell; A Cutrell; D Thorborn; R Isaacs; S Hetherington; H Steel; W Spreen
Journal:  JAMA       Date:  2001-03-07       Impact factor: 56.272

7.  Enantioselective resolution of γ-lactam by a whole cell of Microbacterium hydrocarbonoxydans (L29-9) immobilized in polymer of PVA-alginate-boric acid.

Authors:  Xiaoxi Qin; Jianjun Wang; Guojun Zheng
Journal:  Appl Biochem Biotechnol       Date:  2010-06-20       Impact factor: 2.926

8.  The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site.

Authors:  Kirsty Line; Michail N Isupov; Jennifer A Littlechild
Journal:  J Mol Biol       Date:  2004-04-30       Impact factor: 5.469

9.  Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product.

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Journal:  Eur J Biochem       Date:  1993-10-01

Review 10.  The enzymatic synthesis of antiviral agents.

Authors:  J R Hanrahan; D W Hutchinson
Journal:  J Biotechnol       Date:  1992-04       Impact factor: 3.307
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  6 in total

Review 1.  Dynamic kinetic resolution of Vince lactam catalyzed by γ-lactamases: a mini-review.

Authors:  Shaozhou Zhu; Guojun Zheng
Journal:  J Ind Microbiol Biotechnol       Date:  2018-10-23       Impact factor: 3.346

2.  Engineering the Enantioselectivity and Thermostability of a (+)-γ-Lactamase from Microbacterium hydrocarbonoxydans for Kinetic Resolution of Vince Lactam (2-Azabicyclo[2.2.1]hept-5-en-3-one).

Authors:  Shuaihua Gao; Shaozhou Zhu; Rong Huang; Hongxia Li; Hao Wang; Guojun Zheng
Journal:  Appl Environ Microbiol       Date:  2017-12-15       Impact factor: 4.792

3.  Structural insights into the γ-lactamase activity and substrate enantioselectivity of an isochorismatase-like hydrolase from Microbacterium hydrocarbonoxydans.

Authors:  Shuaihua Gao; Yu Zhou; Weiwei Zhang; Wenhe Wang; You Yu; Yajuan Mu; Hao Wang; Xinqi Gong; Guojun Zheng; Yue Feng
Journal:  Sci Rep       Date:  2017-03-15       Impact factor: 4.379

4.  Converting the E. coli Isochorismatase Nicotinamidase into γ-Lactamase.

Authors:  Xiaoyan Guo; Licao Chang; Haibo Jin; Junge Zhu; Yong Tao; Sheng Wu; Jianjun Wang
Journal:  Microbiol Spectr       Date:  2022-02-16

5.  CBD binding domain fused γ-lactamase from Sulfolobus solfataricus is an efficient catalyst for (-) γ-lactam production.

Authors:  Jianjun Wang; Junge Zhu; Cong Min; Sheng Wu
Journal:  BMC Biotechnol       Date:  2014-05-13       Impact factor: 2.563

6.  Construction of an organelle-like nanodevice via supramolecular self-assembly for robust biocatalysts.

Authors:  Hongxia Li; Guojun Zheng; Shaozhou Zhu
Journal:  Microb Cell Fact       Date:  2018-02-20       Impact factor: 5.328
  6 in total

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