Literature DB >> 22874136

The landscape for epigenetic/epigenomic biomedical resources.

Kabita Shakya1, Mary J O'Connell, Heather J Ruskin.   

Abstract

Recent advances in molecular biology and computational power have seen the biomedical sector enter a new era, with corresponding development of Bioinformatics as a major discipline. Generation of enormous amounts of data has driven the need for more advanced storage solutions and shared access through a range of public repositories. The number of such biomedical resources is increasing constantly and mining these large and diverse data sets continues to present real challenges. This paper attempts a general overview of currently available resources, together with remarks on their data mining and analysis capabilities. Of interest here is the recent shift in focus from genetic to epigenetic/epigenomic research and the emergence and extension of resource provision to support this both at local and global scale. Biomedical text and numerical data mining are both considered, the first dealing with automated methods for analyzing research content and information extraction, and the second (broadly) with pattern recognition and prediction. Any summary and selection of resources is inherently limited, given the spectrum available, but the aim is to provide a guideline for the assessment and comparison of currently available provision, particularly as this relates to epigenetics/epigenomics.

Mesh:

Year:  2012        PMID: 22874136      PMCID: PMC3515018          DOI: 10.4161/epi.21493

Source DB:  PubMed          Journal:  Epigenetics        ISSN: 1559-2294            Impact factor:   4.528


  12 in total

Review 1.  Genomic imprinting: parental influence on the genome.

Authors:  W Reik; J Walter
Journal:  Nat Rev Genet       Date:  2001-01       Impact factor: 53.242

Review 2.  The history of cancer epigenetics.

Authors:  Andrew P Feinberg; Benjamin Tycko
Journal:  Nat Rev Cancer       Date:  2004-02       Impact factor: 60.716

Review 3.  Epigenetics and human disease: translating basic biology into clinical applications.

Authors:  David Rodenhiser; Mellissa Mann
Journal:  CMAJ       Date:  2006-01-31       Impact factor: 8.262

4.  The MethDB DAS server: adding an epigenetic information layer to the human genome.

Authors:  Vincent Negre; Christoph Grunau
Journal:  Epigenetics       Date:  2006-04-05       Impact factor: 4.528

5.  MethDB--a public database for DNA methylation data.

Authors:  C Grunau; E Renault; A Rosenthal; G Roizes
Journal:  Nucleic Acids Res       Date:  2001-01-01       Impact factor: 16.971

6.  The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.

Authors:  Jessica D Tenenbaum; Patricia L Whetzel; Kent Anderson; Charles D Borromeo; Ivo D Dinov; Davera Gabriel; Beth Kirschner; Barbara Mirel; Tim Morris; Natasha Noy; Csongor Nyulas; David Rubenson; Paul R Saxman; Harpreet Singh; Nancy Whelan; Zach Wright; Brian D Athey; Michael J Becich; Geoffrey S Ginsburg; Mark A Musen; Kevin A Smith; Alice F Tarantal; Daniel L Rubin; Peter Lyster
Journal:  J Biomed Inform       Date:  2010-10-16       Impact factor: 6.317

Review 7.  Epigenetics in human disease and prospects for epigenetic therapy.

Authors:  Gerda Egger; Gangning Liang; Ana Aparicio; Peter A Jones
Journal:  Nature       Date:  2004-05-27       Impact factor: 49.962

Review 8.  Epigenomics: genome-wide study of methylation phenomena.

Authors:  K L Novik; I Nimmrich; B Genc; S Maier; C Piepenbrock; A Olek; S Beck
Journal:  Curr Issues Mol Biol       Date:  2002-10       Impact factor: 2.081

9.  The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations.

Authors:  Rivka L Glaser; Joshua P Ramsay; Ian M Morison
Journal:  Nucleic Acids Res       Date:  2006-01-01       Impact factor: 16.971

10.  MethyCancer: the database of human DNA methylation and cancer.

Authors:  Ximiao He; Suhua Chang; Jiajie Zhang; Qian Zhao; Haizhen Xiang; Kanthida Kusonmano; Liu Yang; Zhong Sheng Sun; Huanming Yang; Jing Wang
Journal:  Nucleic Acids Res       Date:  2007-09-21       Impact factor: 16.971

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  2 in total

Review 1.  Above the Epitranscriptome: RNA Modifications and Stem Cell Identity.

Authors:  Francesco Morena; Chiara Argentati; Martina Bazzucchi; Carla Emiliani; Sabata Martino
Journal:  Genes (Basel)       Date:  2018-06-28       Impact factor: 4.096

2.  Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.

Authors:  Liming Chen; Pei Wang; Raman Bahal; José E Manautou; Xiao-Bo Zhong
Journal:  PLoS One       Date:  2019-12-31       Impact factor: 3.240

  2 in total

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