Literature DB >> 22873283

Cobalt-catalyzed ortho-arylation of aromatic imines with aryl chlorides.

Ke Gao1, Pin-Sheng Lee, Chong Long, Naohiko Yoshikai.   

Abstract

An ortho-arylation reaction of aromatic imines with aryl chlorides has been achieved using a cobalt-N-heterocyclic carbene catalyst in combination with a neopentyl Grignard reagent. The reaction takes place at room temperature to afford biaryl products in moderate to good yields.

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Year:  2012        PMID: 22873283     DOI: 10.1021/ol301934y

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

Review 1.  N-Heterocyclic Carbene Complexes in C-H Activation Reactions.

Authors:  Qun Zhao; Guangrong Meng; Steven P Nolan; Michal Szostak
Journal:  Chem Rev       Date:  2020-01-22       Impact factor: 60.622

2.  Palladium-catalyzed direct C-H arylation of cyclic enaminones with aryl iodides.

Authors:  Yi-Yun Yu; Lei Bi; Gunda I Georg
Journal:  J Org Chem       Date:  2013-06-10       Impact factor: 4.354

3.  LiCl-Accelerated Multimetallic Cross-Coupling of Aryl Chlorides with Aryl Triflates.

Authors:  Liangbin Huang; Laura K G Ackerman; Kai Kang; Astrid M Parsons; Daniel J Weix
Journal:  J Am Chem Soc       Date:  2019-07-09       Impact factor: 15.419

4.  Cobalt-catalyzed directed C-H alkenylation of pivalophenone N-H imine with alkenyl phosphates.

Authors:  Wengang Xu; Naohiko Yoshikai
Journal:  Beilstein J Org Chem       Date:  2018-03-28       Impact factor: 2.883

5.  Pivalophenone imine as a benzonitrile surrogate for directed C-H bond functionalization.

Authors:  Wengang Xu; Naohiko Yoshikai
Journal:  Chem Sci       Date:  2017-05-30       Impact factor: 9.825

  5 in total

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