Literature DB >> 22868271

PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes.

Jinsuk Kang1, Sundeep Kalantry, Anjana Rao.   

Abstract

In zygotes, a global loss of DNA methylation occurs selectively in the paternal pronucleus before the first cell division, concomitantly with the appearance of modified forms of 5-methylcytosine. The adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Nakamura et al. recently clarified the molecular mechanism involved: PGC7/Stella/Dppa3 binds to dimethylated histone 3 lysine 9 (H3K9me2), thereby blocking the activity of the Tet3 methylcytosine oxidase in the maternal genome as well as at certain imprinted loci in the paternal genome.

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Year:  2012        PMID： 22868271      PMCID： PMC3541665          DOI： 10.1038/cr.2012.117

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  15 in total

1.  Demethylation of the zygotic paternal genome.

Authors:  W Mayer; A Niveleau; J Walter; R Fundele; T Haaf
Journal:  Nature       Date:  2000-02-03       Impact factor: 49.962

2.  PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.

Authors:  Toshinobu Nakamura; Yu-Jung Liu; Hiroyuki Nakashima; Hiroki Umehara; Kimiko Inoue; Shogo Matoba; Makoto Tachibana; Atsuo Ogura; Yoichi Shinkai; Toru Nakano
Journal:  Nature       Date:  2012-06-03       Impact factor: 49.962

Review 3.  Mammalian cytosine methylation at a glance.

Authors:  Steen K T Ooi; Anne H O'Donnell; Timothy H Bestor
Journal:  J Cell Sci       Date:  2009-08-15       Impact factor: 5.285

4.  PGC7/Stella protects against DNA demethylation in early embryogenesis.

Authors:  Toshinobu Nakamura; Yoshikazu Arai; Hiroki Umehara; Masaaki Masuhara; Tohru Kimura; Hisaaki Taniguchi; Toshihiro Sekimoto; Masahito Ikawa; Yoshihiro Yoneda; Masaru Okabe; Satoshi Tanaka; Kunio Shiota; Toru Nakano
Journal:  Nat Cell Biol       Date:  2006-12-03       Impact factor: 28.824

5.  Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.

Authors:  Khursheed Iqbal; Seung-Gi Jin; Gerd P Pfeifer; Piroska E Szabó
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-14       Impact factor: 11.205

6.  Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Authors:  Mamta Tahiliani; Kian Peng Koh; Yinghua Shen; William A Pastor; Hozefa Bandukwala; Yevgeny Brudno; Suneet Agarwal; Lakshminarayan M Iyer; David R Liu; L Aravind; Anjana Rao
Journal:  Science       Date:  2009-04-16       Impact factor: 47.728

Review 7.  Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes.

Authors:  Lakshminarayan M Iyer; Vivek Anantharaman; Maxim Y Wolf; L Aravind
Journal:  Int J Parasitol       Date:  2007-09-15       Impact factor: 3.981

8.  Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states.

Authors:  Katsuhiko Hayashi; Susana M Chuva de Sousa Lopes; Fuchou Tang; Kaiqin Lao; M Azim Surani
Journal:  Cell Stem Cell       Date:  2008-10-09       Impact factor: 24.633

9.  Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids.

Authors:  Lakshminarayan M Iyer; Mamta Tahiliani; Anjana Rao; L Aravind
Journal:  Cell Cycle       Date:  2009-06-27       Impact factor: 4.534

10.  Distinctive chromatin in human sperm packages genes for embryo development.

Authors:  Saher Sue Hammoud; David A Nix; Haiying Zhang; Jahnvi Purwar; Douglas T Carrell; Bradley R Cairns
Journal:  Nature       Date:  2009-06-14       Impact factor: 49.962
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  11 in total

1.  Embryonic defects induced by maternal obesity in mice derive from Stella insufficiency in oocytes.

Authors:  Longsen Han; Chao Ren; Ling Li; Xiaoyan Li; Juan Ge; Haichao Wang; Yi-Liang Miao; Xuejiang Guo; Kelle H Moley; Wenjie Shu; Qiang Wang
Journal:  Nat Genet       Date:  2018-02-19       Impact factor: 38.330

2.  Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.

Authors:  Shona H Wood; Sipko van Dam; Thomas Craig; Robi Tacutu; Amy O'Toole; Brian J Merry; João Pedro de Magalhães
Journal:  Genome Biol       Date:  2015-12-22       Impact factor: 13.583

Review 3.  Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life.

Authors:  Joselyn Rojas; Mervin Chávez-Castillo; Luis Carlos Olivar; María Calvo; José Mejías; Milagros Rojas; Jessenia Morillo; Valmore Bermúdez
Journal:  J Pregnancy       Date:  2015-12-01

4.  MAD2L2 Promotes Open Chromatin in Embryonic Stem Cells and Derepresses the Dppa3 Locus.

Authors:  Ali Rahjouei; Mehdi Pirouz; Michela Di Virgilio; Dirk Kamin; Michael Kessel
Journal:  Stem Cell Reports       Date:  2017-03-16       Impact factor: 7.765

5.  Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.

Authors:  Wei-Hung Pan; Felix Sommer; Maren Falk-Paulsen; Thomas Ulas; Philipp Best; Antonella Fazio; Priyadarshini Kachroo; Anne Luzius; Marlene Jentzsch; Ateequr Rehman; Fabian Müller; Thomas Lengauer; Jörn Walter; Sven Künzel; John F Baines; Stefan Schreiber; Andre Franke; Joachim L Schultze; Fredrik Bäckhed; Philip Rosenstiel
Journal:  Genome Med       Date:  2018-04-13       Impact factor: 11.117

6.  GSE is a maternal factor involved in active DNA demethylation in zygotes.

Authors:  Yuki Hatanaka; Natsumi Shimizu; Satoshi Nishikawa; Mikiko Tokoro; Seung-Wook Shin; Takuji Nishihara; Tomoko Amano; Masayuki Anzai; Hiromi Kato; Tasuku Mitani; Yoshihiko Hosoi; Satoshi Kishigami; Kazuya Matsumoto
Journal:  PLoS One       Date:  2013-04-01       Impact factor: 3.240

7.  Hypoxia causes transgenerational impairments in reproduction of fish.

Authors:  Simon Yuan Wang; Karen Lau; Keng-Po Lai; Jiang-Wen Zhang; Anna Chung-Kwan Tse; Jing-Woei Li; Yin Tong; Ting-Fung Chan; Chris Kong-Chu Wong; Jill Man-Ying Chiu; Doris Wai-Ting Au; Alice Sze-Tsai Wong; Richard Yuen-Chong Kong; Rudolf Shiu-Sun Wu
Journal:  Nat Commun       Date:  2016-07-04       Impact factor: 14.919

8.  The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse Zygotes.

Authors:  Xue-Shan Ma; Shi-Bin Chao; Xian-Ju Huang; Fei Lin; Ling Qin; Xu-Guang Wang; Tie-Gang Meng; Cheng-Cheng Zhu; Heide Schatten; Hong-Lin Liu; Qing-Yuan Sun
Journal:  Sci Rep       Date:  2015-12-07       Impact factor: 4.379

9.  Effect of TET inhibitor on bovine parthenogenetic embryo development.

Authors:  Jian Zhang; Sheng Zhang; Yutian Wang; Hui Cheng; Linlin Hao; Yanhui Zhai; Zhiren Zhang; Xinglan An; Xiaoling Ma; Xueming Zhang; Ziyi Li; Bo Tang
Journal:  PLoS One       Date:  2017-12-21       Impact factor: 3.240

Review 10.  The Vast Complexity of the Epigenetic Landscape during Neurodevelopment: An Open Frame to Understanding Brain Function.

Authors:  Ariel Ernesto Cariaga-Martínez; Kilian Jesús Gutiérrez; Raúl Alelú-Paz
Journal:  Int J Mol Sci       Date:  2018-05-01       Impact factor: 5.923
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