Literature DB >> 22867945

Targeting Jab1/CSN5 in nasopharyngeal carcinoma.

Yunbao Pan1, Francois X Claret.   

Abstract

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated head and neck cancer that is most common in eastern Asia. Epstein-Barr virus infection, environmental factors, and genetic susceptibility play important roles in NPC pathogenesis. Jab1/CSN5 is a multifunctional protein that participates in affecting integrin signaling, controlling cell proliferation and apoptosis, and regulating genomic instability and DNA repair. Correlation of Jab1/CSN5 overexpression with poor prognosis for NPC provides evidence that it is involved in the tumorigenic process. In this review, we highlight recent advances in studies of the oncogenic role of Jab1/CSN5 in NPC and its potential as a therapeutic target for this cancer. Published by Elsevier Ireland Ltd.

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Year:  2012        PMID： 22867945      PMCID： PMC3474602          DOI： 10.1016/j.canlet.2012.07.033

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  69 in total

1.  Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1.

Authors:  K Tomoda; Y Kubota; J Kato
Journal:  Nature       Date:  1999-03-11       Impact factor: 49.962

2.  Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1.

Authors:  R Kleemann; A Hausser; G Geiger; R Mischke; A Burger-Kentischer; O Flieger; F J Johannes; T Roger; T Calandra; A Kapurniotu; M Grell; D Finkelmeier; H Brunner; J Bernhagen
Journal:  Nature       Date:  2000-11-09       Impact factor: 49.962

3.  JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression.

Authors:  Selina Sitte; Joachim Gläsner; Julia Jellusova; Florian Weisel; Martina Panattoni; Ruggero Pardi; André Gessner
Journal:  J Immunol       Date:  2012-02-10       Impact factor: 5.422

4.  The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.

Authors:  Sergey Doronkin; Inna Djagaeva; Steven K Beckendorf
Journal:  Dev Cell       Date:  2003-05       Impact factor: 12.270

Review 5.  The COP9 signalosome.

Authors:  Ning Wei; Xing Wang Deng
Journal:  Annu Rev Cell Dev Biol       Date:  2003       Impact factor: 13.827

6.  The National Cancer Data Base report on the relationship of race and national origin to the histology of nasopharyngeal carcinoma.

Authors:  J E Marks; J L Phillips; H R Menck
Journal:  Cancer       Date:  1998-08-01       Impact factor: 6.860

7.  Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations.

Authors:  S F Kwok; R Solano; T Tsuge; D A Chamovitz; J R Ecker; M Matsui; X W Deng
Journal:  Plant Cell       Date:  1998-11       Impact factor: 11.277

8.  Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma.

Authors:  Jihyun Ahn; Soon Auck Hong; Seung-Eun Lee; Jaetaek Kim; Yeon Sahng Oh; Sung Jun Park; Yun Jae Chung
Journal:  Endocr J       Date:  2009-05-20       Impact factor: 2.349

9.  Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells.

Authors:  Terry J Shackleford; Qingxiu Zhang; Ling Tian; Thuy T Vu; Anita L Korapati; Angela M Baumgartner; Xiao-Feng Le; Warren S Liao; Francois X Claret
Journal:  Breast Cancer Res       Date:  2011-06-20       Impact factor: 6.466

10.  CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint.

Authors:  Sergey Doronkin; Inna Djagaeva; Steven K Beckendorf
Journal:  Development       Date:  2002-11       Impact factor: 6.868
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  24 in total

1.  Reverse correlation of Jab1 and Smad4 in PANC-1 cells involved in the pathogenesis of pancreatic cancer.

Authors:  Jun Li; Zhuoyu Gu; Siyuan Li; Zhiwei Xiao; Kan Sun
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

2.  CSN5 Promotes Hepatocellular Carcinoma Progression by SCARA5 Inhibition Through Suppressing β-Catenin Ubiquitination.

Authors:  Hongliang Liu; Junwen Hu; Hua Pan; Dilai Luo; Mingwen Huang; Wei Xu
Journal:  Dig Dis Sci       Date:  2017-11-30       Impact factor: 3.199

3.  Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation.

Authors:  Sumei Wang; Rong Zhang; Francois X Claret; Huiling Yang
Journal:  Mol Cancer Ther       Date:  2014-10-15       Impact factor: 6.261

Review 4.  The emerging roles of Jab1/CSN5 in cancer.

Authors:  Lin Wang; Jun-Nian Zheng; Dong-Sheng Pei
Journal:  Med Oncol       Date:  2016-07-13       Impact factor: 3.064

5.  Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling.

Authors:  Craig Gutierrez; Ilan E Chemmama; Haibin Mao; Clinton Yu; Ignacia Echeverria; Sarah A Block; Scott D Rychnovsky; Ning Zheng; Andrej Sali; Lan Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-07       Impact factor: 11.205

6.  An overactive neddylation pathway serves as a therapeutic target and MLN4924 enhances the anticancer activity of cisplatin in pancreatic cancer.

Authors:  Yu Zeng; Yong-Shuang Iv; Qi-Hua Pan; Yi-Guo Zhou; He Li
Journal:  Oncol Lett       Date:  2019-07-09       Impact factor: 2.967

Review 7.  Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer.

Authors:  Yunbao Pan; Huiling Yang; Francois X Claret
Journal:  Cancer Biol Ther       Date:  2014-02-04       Impact factor: 4.742

Review 8.  Jab1/Cops5: a promising target for cancer diagnosis and therapy.

Authors:  Chunjue Yuan; Dong Wang; Guohong Liu; Yunbao Pan
Journal:  Int J Clin Oncol       Date:  2021-05-21       Impact factor: 3.402

9.  Quantitative expression analysis and prognostic significance of the BCL2-associated X gene in nasopharyngeal carcinoma: a retrospective cohort study.

Authors:  Christos K Kontos; Ali Fendri; Abdelmajid Khabir; Raja Mokdad-Gargouri; Andreas Scorilas
Journal:  BMC Cancer       Date:  2013-06-18       Impact factor: 4.430

10.  Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma.

Authors:  Yunbao Pan; Fuling Zhou; Ronghua Zhang; Francois X Claret
Journal:  PLoS One       Date:  2013-01-29       Impact factor: 3.240
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