A Skwierawska1, A Pazik. 1. Department of Chemical Technology, Gdansk University of Technology, G. Narutowicza Street 11/12, 80-233 Gdansk, Poland.
Abstract
N-Alkyltheobromine (1-9) derivatives were obtained by reacting theobromine with appropriate alkyl halide under microwave irradiation at 100-150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The presented compounds 1-5 have been studied as ion carriers in ion-selective membrane electrodes. Selectivity of these membranes was studied towards various anions in addition to transition and heavy metal cations. GRAPHICAL ABSTRACT: Alkylations of theobromine under microwave irradiation at 100-150 W and by conventional synthesis were performed. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were observed. The achieved compounds have been studied as ion carriers in ion-selective membrane electrodes.
N-Alkyltheobromine (1-9) derivatives were obtained by reacting n class="Chemical">theobromine with appropriate alkyl halide under microwave irradiation at 100-150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The presented compounds 1-5 have been studied as ion carriers in ion-selective membrane electrodes. Selectivity of these membranes was studied towards various anions in addition to transition and heavy metal cations. GRAPHICAL ABSTRACT: Alkylations of theobromine under microwave irradiation at 100-150 W and by conventional synthesis were performed. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were observed. The achieved compounds have been studied as ion carriers in ion-selective membrane electrodes.
Authors: R M Strieter; D G Remick; P A Ward; R N Spengler; J P Lynch; J Larrick; S L Kunkel Journal: Biochem Biophys Res Commun Date: 1988-09-30 Impact factor: 3.575