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Literature DB >> 22864916

Effect of CC chemokine receptor 4 antagonism on the evolution of experimental autoimmune encephalomyelitis.

Shivashankar Othy, Selma Topçu, Srini V Kaveri, Jagadeesh Bayry.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2012 PMID： 22864916 PMCID： PMC3443131 DOI： 10.1073/pnas.1209124109

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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5 in total

1. Racemic and chiral lactams as potent, selective and functionally active CCR4 antagonists.

Authors: Bradley Newhouse; Shelley Allen; Benjamin Fauber; Aaron S Anderson; C Todd Eary; Joshua D Hansen; Justin Schiro; John J Gaudino; Ellen Laird; David Chantry; Christine Eberhardt; Laurence E Burgess
Journal: Bioorg Med Chem Lett Date: 2004-11-15 Impact factor: 2.823

2. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.

Authors: Helene Pere; Yves Montier; Jagadeesh Bayry; Francoise Quintin-Colonna; Nathalie Merillon; Estelle Dransart; Cecile Badoual; Alain Gey; Patrice Ravel; Elie Marcheteau; Frederic Batteux; Federico Sandoval; Olivier Adotevi; Christopher Chiu; Sylvie Garcia; Corinne Tanchot; Yu-Chun Lone; Luis Carlos Ferreira; Brad H Nelson; Douglas Hanahan; Wolf Herman Fridman; Ludger Johannes; Eric Tartour
Journal: Blood Date: 2011-09-09 Impact factor: 22.113

3. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.

Authors: Karola Poppensieker; David-Marian Otte; Britta Schürmann; Andreas Limmer; Philipp Dresing; Eva Drews; Beatrix Schumak; Luisa Klotz; Jennifer Raasch; Alexander Mildner; Ari Waisman; Stefanie Scheu; Percy Knolle; Irmgard Förster; Marco Prinz; Wolfgang Maier; Andreas Zimmer; Judith Alferink
Journal: Proc Natl Acad Sci U S A Date: 2012-02-21 Impact factor: 11.205

4. In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination.

Authors: Jagadeesh Bayry; Elma Z Tchilian; Matthew N Davies; Emily K Forbes; Simon J Draper; Srini V Kaveri; Adrian V S Hill; Michel D Kazatchkine; Peter C L Beverley; Darren R Flower; David F Tough
Journal: Proc Natl Acad Sci U S A Date: 2008-07-11 Impact factor: 11.205

5. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells.

Authors: A Iellem; M Mariani; R Lang; H Recalde; P Panina-Bordignon; F Sinigaglia; D D'Ambrosio
Journal: J Exp Med Date: 2001-09-17 Impact factor: 14.307

5 in total

4 in total

Effect of CC chemokine receptor 4 antagonism on the evolution of experimental autoimmune encephalomyelitis.

1. Racemic and chiral lactams as potent, selective and functionally active CCR4 antagonists.

2. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.

3. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.

4. In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination.

5. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells.

Review 1. The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity.

2. Sex differences in EAE reveal common and distinct cellular and molecular components.

Review 3. Regulatory T cells as adjuvant target for enhancing the viral disease vaccine efficacy.

Review 4. The role of chemokines and chemokine receptors in multiple sclerosis.