Literature DB >> 22859199

Alzheimer's disease: A protective mutation.

Bart De Strooper, Thierry Voet.   

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Year:  2012        PMID： 22859199     DOI： 10.1038/488038a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  15 in total

Review 1.  The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes.

Authors:  Iryna Benilova; Eric Karran; Bart De Strooper
Journal:  Nat Neurosci       Date:  2012-01-29       Impact factor: 24.884

2.  A new multipoint method for genome-wide association studies by imputation of genotypes.

Authors:  Jonathan Marchini; Bryan Howie; Simon Myers; Gil McVean; Peter Donnelly
Journal:  Nat Genet       Date:  2007-06-17       Impact factor: 38.330

Review 3.  The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics.

Authors:  Eric Karran; Marc Mercken; Bart De Strooper
Journal:  Nat Rev Drug Discov       Date:  2011-08-19       Impact factor: 84.694

4.  A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.

Authors:  Thorlakur Jonsson; Jasvinder K Atwal; Stacy Steinberg; Jon Snaedal; Palmi V Jonsson; Sigurbjorn Bjornsson; Hreinn Stefansson; Patrick Sulem; Daniel Gudbjartsson; Janice Maloney; Kwame Hoyte; Amy Gustafson; Yichin Liu; Yanmei Lu; Tushar Bhangale; Robert R Graham; Johanna Huttenlocher; Gyda Bjornsdottir; Ole A Andreassen; Erik G Jönsson; Aarno Palotie; Timothy W Behrens; Olafur T Magnusson; Augustine Kong; Unnur Thorsteinsdottir; Ryan J Watts; Kari Stefansson
Journal:  Nature       Date:  2012-08-02       Impact factor: 49.962

Review 5.  Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

Authors:  Christian Haass; Dennis J Selkoe
Journal:  Nat Rev Mol Cell Biol       Date:  2007-02       Impact factor: 94.444

6.  A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.

Authors:  Giuseppe Di Fede; Marcella Catania; Michela Morbin; Giacomina Rossi; Silvia Suardi; Giulia Mazzoleni; Marco Merlin; Anna Rita Giovagnoli; Sara Prioni; Alessandra Erbetta; Chiara Falcone; Marco Gobbi; Laura Colombo; Antonio Bastone; Marten Beeg; Claudia Manzoni; Bruna Francescucci; Alberto Spagnoli; Laura Cantù; Elena Del Favero; Efrat Levy; Mario Salmona; Fabrizio Tagliavini
Journal:  Science       Date:  2009-03-13       Impact factor: 47.728

7.  Detection of sharing by descent, long-range phasing and haplotype imputation.

Authors:  Augustine Kong; Gisli Masson; Michael L Frigge; Arnaldur Gylfason; Pasha Zusmanovich; Gudmar Thorleifsson; Pall I Olason; Andres Ingason; Stacy Steinberg; Thorunn Rafnar; Patrick Sulem; Magali Mouy; Frosti Jonsson; Unnur Thorsteinsdottir; Daniel F Gudbjartsson; Hreinn Stefansson; Kari Stefansson
Journal:  Nat Genet       Date:  2008-09       Impact factor: 38.330

Review 8.  The amyloid state of proteins in human diseases.

Authors:  David Eisenberg; Mathias Jucker
Journal:  Cell       Date:  2012-03-16       Impact factor: 41.582

Review 9.  Twenty years of Alzheimer's disease-causing mutations.

Authors:  Alison Goate; John Hardy
Journal:  J Neurochem       Date:  2011-11-28       Impact factor: 5.372

10.  The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.

Authors:  Lucía Chávez-Gutiérrez; Leen Bammens; Iryna Benilova; Annelies Vandersteen; Manasi Benurwar; Marianne Borgers; Sam Lismont; Lujia Zhou; Simon Van Cleynenbreugel; Hermann Esselmann; Jens Wiltfang; Lutgarde Serneels; Eric Karran; Harrie Gijsen; Joost Schymkowitz; Frederic Rousseau; Kerensa Broersen; Bart De Strooper
Journal:  EMBO J       Date:  2012-04-13       Impact factor: 11.598
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  12 in total

1.  Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage.

Authors:  Wen Yao; Marc D Tambini; Xinran Liu; Luciano D'Adamio
Journal:  J Neurosci       Date:  2019-06-24       Impact factor: 6.167

2.  The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation.

Authors:  Iryna Benilova; Rodrigo Gallardo; Andreea-Alexandra Ungureanu; Virginia Castillo Cano; An Snellinx; Meine Ramakers; Carmen Bartic; Frederic Rousseau; Joost Schymkowitz; Bart De Strooper
Journal:  J Biol Chem       Date:  2014-09-24       Impact factor: 5.157

Review 3.  Individualized medicine from prewomb to tomb.

Authors:  Eric J Topol
Journal:  Cell       Date:  2014-03-27       Impact factor: 41.582

4.  Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

Authors:  Dolores Del Prete; Richard C Rice; Anjali M Rajadhyaksha; Luciano D'Adamio
Journal:  J Biol Chem       Date:  2016-06-20       Impact factor: 5.157

5.  Alzheimer's protective A2T mutation changes the conformational landscape of the Aβ₁₋₄₂ monomer differently than does the A2V mutation.

Authors:  Payel Das; Brian Murray; Georges Belfort
Journal:  Biophys J       Date:  2015-02-03       Impact factor: 4.033

Review 6.  An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases.

Authors:  Bidur Bhandary; Anu Marahatta; Hyung-Ryong Kim; Han-Jung Chae
Journal:  Int J Mol Sci       Date:  2012-12-24       Impact factor: 5.923

7.  Characterization of hippocampal Cajal-Retzius cells during development in a mouse model of Alzheimer's disease (Tg2576).

Authors:  Dongming Yu; Wenjuan Fan; Ping Wu; Jiexin Deng; Jing Liu; Yanli Niu; Mingshan Li; Jinbo Deng
Journal:  Neural Regen Res       Date:  2014-02-15       Impact factor: 5.135

Review 8.  Endoplasmic Reticulum Stress and Associated ROS.

Authors:  Hafiz Maher Ali Zeeshan; Geum Hwa Lee; Hyung-Ryong Kim; Han-Jung Chae
Journal:  Int J Mol Sci       Date:  2016-03-02       Impact factor: 5.923

9.  APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses.

Authors:  Tomas Fanutza; Dolores Del Prete; Michael J Ford; Pablo E Castillo; Luciano D'Adamio
Journal:  Elife       Date:  2015-11-09       Impact factor: 8.140

10.  Deletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementia.

Authors:  Fabrizio Biundo; Keita Ishiwari; Dolores Del Prete; Luciano D'Adamio
Journal:  Oncotarget       Date:  2016-03-15
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