Literature DB >> 2285300

Magainin analogs effective against pathogenic protozoa.

C M Huang1, H C Chen, C H Zierdt.   

Abstract

The in vitro activities of magainin analogs against Blastocystis hominis, Entamoeba histolytica, and Trypanosoma cruzi were assessed by protozoan morphological integrity and motility. The antiprotozoan activities in descending order were magainin B greater than G greater than H, the same order as the alpha-helix contents of the analogs. Magainin B and G were effective against B. hominis, T. cruzi, and E. histolytica.

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Year:  1990        PMID： 2285300      PMCID： PMC171939          DOI： 10.1128/AAC.34.9.1824

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Magainin 1-induced leakage of entrapped calcein out of negatively-charged lipid vesicles.

Authors:  K Matsuzaki; M Harada; T Handa; S Funakoshi; N Fujii; H Yajima; K Miyajima
Journal:  Biochim Biophys Acta       Date:  1989-05-19

2.  Synthetic magainin analogues with improved antimicrobial activity.

Authors:  H C Chen; J H Brown; J L Morell; C M Huang
Journal:  FEBS Lett       Date:  1988-08-29       Impact factor: 4.124

3.  Antimicrobial activity of synthetic magainin peptides and several analogues.

Authors:  M Zasloff; B Martin; H C Chen
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

4.  Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

Authors:  M Zasloff
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

5.  Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones.

Authors:  M G Giovannini; L Poulter; B W Gibson; D H Williams
Journal:  Biochem J       Date:  1987-04-01       Impact factor: 3.857

6.  Cytochrome-free mitochondria of an anaerobic protozoan--Blastocystis hominis.

Authors:  C H Zierdt
Journal:  J Protozool       Date:  1986-02

7.  Techniques of axenic cultivation of Entamoeba histolytica Schaudinn, 1903 and E. histolytica-like amebae.

Authors:  L S Diamond
Journal:  J Parasitol       Date:  1968-10       Impact factor: 1.276
  7 in total
  6 in total

1.  Role of positional hydrophobicity in the leishmanicidal activity of magainin 2.

Authors:  Esther Guerrero; José María Saugar; Katsumi Matsuzaki; Luis Rivas
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

Review 2.  Multifunctional antimicrobial peptides: therapeutic targets in several human diseases.

Authors:  Mohamed Zaiou
Journal:  J Mol Med (Berl)       Date:  2007-01-10       Impact factor: 4.599

Review 3.  Immunomodulatory and Allergenic Properties of Antimicrobial Peptides.

Authors:  Svetlana V Guryanova; Tatiana V Ovchinnikova
Journal:  Int J Mol Sci       Date:  2022-02-24       Impact factor: 5.923

4.  Blastocystis Isolate B Exhibits Multiple Modes of Resistance against Antimicrobial Peptide LL-37.

Authors:  John Anthony Yason; Sitara Swarna Rao Ajjampur; Kevin Shyong Wei Tan
Journal:  Infect Immun       Date:  2016-07-21       Impact factor: 3.441

5.  Plasma membrane damage repair is mediated by an acid sphingomyelinase in Entamoeba histolytica.

Authors:  Fátima Ramírez-Montiel; Claudia Mendoza-Macías; Sairy Andrade-Guillén; Ángeles Rangel-Serrano; Itzel Páramo-Pérez; Paris E Rivera-Cuéllar; B Liliana España-Sánchez; Gabriel Luna-Bárcenas; Fernando Anaya-Velázquez; Bernardo Franco; Felipe Padilla-Vaca
Journal:  PLoS Pathog       Date:  2019-08-28       Impact factor: 6.823

6.  Pleiotropic effects of Blastocystis spp. Subtypes 4 and 7 on ligand-specific toll-like receptor signaling and NF-κB activation in a human monocyte cell line.

Authors:  Joshua D W Teo; Paul A Macary; Kevin S W Tan
Journal:  PLoS One       Date:  2014-02-14       Impact factor: 3.240
  6 in total

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