Literature DB >> 22851819

Prevention of Parent to Child Transmission of HIV (PPTCT): An Effort of 4 Years in a Tertiary Centre.

Sebanti Goswami, Partha Sarathi Chakravorty.   

Abstract

OBJECTIVE: The aim of this study was to see the fetomaternal outcome of pregnancy in HIV positive mother.
METHODS: This study was conducted in the department of OBGYN Medical College Kolkata from 1st January 2004 to 31st December 2007, a period of 4 years since the establishment of PPTCT centre in our institution. All the pregnant women attending the antenatal clinic for consultation and those coming directly to labour room for delivery (unbooked cases) were counseled for HIV testing, informed consent was obtained and blood samples collected for HIV testing. Babies of HIV positive women delivered were followed up to 18 months for testing.
RESULTS: The no. of women detected positive were 28, 53, 69 and 98 (total 248) in the consecutive years. Therefore the seroprevalence of HIV was 0.41, 0.63, 0.67 and 0.76% in 2004, 2005, 2006 and 2007 respectively. Out of 248 women who were detected positive in the 3 years, only 103 (41.53%) delivered in our institution. 32 (12.90%) underwent MTP. But unfortunately 113 (i.e. 248 - (103 + 32) = 113) were lost to follow up during antenatal care. Out of the 95 live births, only 46 babies have been tested so far out of which only one is reactive, 45 are non reactive.
CONCLUSION: The main obstacle we faced was in following up the mother and the baby. To achieve a high success rate, PPTCT programmes must have well-trained, supportive staff who take great care to ensure confidentiality. They must be backed up by effective HIV testing and counseling programmes and by good quality HIV/AIDS education, which is essential to eliminate myths and misunderstandings among pregnant women, and to counter stigma and discrimination in the wider community.

Entities:  

Keywords:  HIV; Prevention of parent to child transmission

Year:  2011        PMID: 22851819      PMCID: PMC3295878          DOI: 10.1007/s13224-011-0056-1

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  2 in total

1.  A multicenter randomized controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1.

Authors:  Dhayendre Moodley; Jagidesa Moodley; Hoosen Coovadia; Glenda Gray; James McIntyre; Justus Hofmyer; Cheryl Nikodem; David Hall; Maria Gigliotti; Patrick Robinson; Lynette Boshoff; John L Sullivan
Journal:  J Infect Dis       Date:  2003-02-24       Impact factor: 5.226

2.  Operational effectiveness of single-dose nevirapine in preventing mother-to-child transmission of HIV.

Authors:  Mark Colvin; Mickey Chopra; Tanya Doherty; Debra Jackson; Jonathan Levin; Juana Willumsen; Ameena Goga; Pravi Moodley
Journal:  Bull World Health Organ       Date:  2007-06       Impact factor: 9.408

  2 in total
  4 in total

1.  A reflection on current obstetrics and gynaecology research in India.

Authors:  Juan F Pacheco-Páramo; Jon Cornwall
Journal:  Australas Med J       Date:  2013-12-31

2.  Prevention of Parent to Child Transmission of HIV: Single Centre Experience of 14 years at Tertiary Care Hospital in Delhi, India.

Authors:  A G Radhika; Sonia Chawla; Sruthi Bhaskaran
Journal:  J Clin Diagn Res       Date:  2017-08-01

Review 3.  The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: a systematic review and meta-analysis.

Authors:  Euphemia L Sibanda; Ian V D Weller; James G Hakim; Frances M Cowan
Journal:  AIDS       Date:  2013-11-13       Impact factor: 4.177

4.  Is it time to bring the "Parent" into the prevention of parent to child transmission programs in India? A study of trends over a 10-year period in a prevention of parent to child transmission clinic in India.

Authors:  Swati Shiradkar; Shubhangi Mande; Gauri Bapat; Maninder Singh Setia
Journal:  Indian J Sex Transm Dis AIDS       Date:  2016 Jan-Jun
  4 in total

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